NU Duncan Lab
@nuduncanlab.bsky.social
The Duncan Lab uses mammalian model systems to investigate what underlies the age-associated decline in female gamete quantity and quality.
Northwestern University Feinberg School of Medicine
Northwestern University Feinberg School of Medicine
The Duncan and Babayev labs wish everyone a very happy and wonderful Thanksgiving!
November 26, 2025 at 3:22 PM
The Duncan and Babayev labs wish everyone a very happy and wonderful Thanksgiving!
Dr. Francesca Duncan and Dr. Hannes Campo received a 2025 Human Advanced In Vitro Model Initiative (HUMAIN) Award! 🎉
Their project aims to create the first human-based ovary–liver co-culture model to study and reverse age-related ovarian fibrosis.
www.pcrm.org/news/news-re...
Their project aims to create the first human-based ovary–liver co-culture model to study and reverse age-related ovarian fibrosis.
www.pcrm.org/news/news-re...
Physicians Committee and InSphero Announce Winners of HUMAIN Award
WASHINGTON, D.C.—The Physicians Committee for Responsible Medicine, a nonprofit that advances human-based science, and InSphero, a global leader in 3D in vitro technology for drug safety and efficacy ...
www.pcrm.org
October 22, 2025 at 4:02 PM
Dr. Francesca Duncan and Dr. Hannes Campo received a 2025 Human Advanced In Vitro Model Initiative (HUMAIN) Award! 🎉
Their project aims to create the first human-based ovary–liver co-culture model to study and reverse age-related ovarian fibrosis.
www.pcrm.org/news/news-re...
Their project aims to create the first human-based ovary–liver co-culture model to study and reverse age-related ovarian fibrosis.
www.pcrm.org/news/news-re...
Reposted by NU Duncan Lab
@MHR_ReprodSci Associate Editors attended the Upper Midwest Summit for Reproductive Science, representing our journal!
Great science and networking opportunity! 🤩
Nardhy Gomez-Lopez Sara Pietroforte Farners Amargant Riera Francesca Duncan
WashU Medicine OBGYN Northwestern Medicine
Great science and networking opportunity! 🤩
Nardhy Gomez-Lopez Sara Pietroforte Farners Amargant Riera Francesca Duncan
WashU Medicine OBGYN Northwestern Medicine
October 21, 2025 at 12:37 AM
@MHR_ReprodSci Associate Editors attended the Upper Midwest Summit for Reproductive Science, representing our journal!
Great science and networking opportunity! 🤩
Nardhy Gomez-Lopez Sara Pietroforte Farners Amargant Riera Francesca Duncan
WashU Medicine OBGYN Northwestern Medicine
Great science and networking opportunity! 🤩
Nardhy Gomez-Lopez Sara Pietroforte Farners Amargant Riera Francesca Duncan
WashU Medicine OBGYN Northwestern Medicine
Dr. Francesca Duncan was interviewed in a segment on the TODAY Show this morning, highlighting her research on ovarian aging at @nu-crs.bsky.social and @buckinstitute.org
Check out the story to learn more about longevity for women!
www.today.com/video/why-ov...
Check out the story to learn more about longevity for women!
www.today.com/video/why-ov...
Why Ovaries, Muscle Mass Could Be Key to Longevity for Women
In the race to live longer and better, two innovators are breaking the mold and focusing on surprising new areas of a woman’s body. Maria Shriver sits down with Francesca Duncan, a top researcher at N...
www.today.com
October 17, 2025 at 3:33 PM
Dr. Francesca Duncan was interviewed in a segment on the TODAY Show this morning, highlighting her research on ovarian aging at @nu-crs.bsky.social and @buckinstitute.org
Check out the story to learn more about longevity for women!
www.today.com/video/why-ov...
Check out the story to learn more about longevity for women!
www.today.com/video/why-ov...
The Duncan Lab showed a strong presence at the Upper Midwest Summit for Reproductive Science, held at Northwestern on October 13 and 14. Prianka Hashim was co-chair and Caroline Kratka won an award for Best Poster.
See the full list of the posters: labs.feinberg.northwestern.edu/duncan/news/...
See the full list of the posters: labs.feinberg.northwestern.edu/duncan/news/...
October 15, 2025 at 5:30 PM
The Duncan Lab showed a strong presence at the Upper Midwest Summit for Reproductive Science, held at Northwestern on October 13 and 14. Prianka Hashim was co-chair and Caroline Kratka won an award for Best Poster.
See the full list of the posters: labs.feinberg.northwestern.edu/duncan/news/...
See the full list of the posters: labs.feinberg.northwestern.edu/duncan/news/...
Organoid models are the way of the future! Check out the Duncan Lab's ovarian somatic organoid model that was highlighted in this exciting News Feature in Nature on the power of reproductive organoids!
www.nature.com/articles/d41...
www.nature.com/articles/d41...
The mini placentas and ovaries revealing the basics of women’s health
Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis.
www.nature.com
September 23, 2025 at 9:50 PM
Organoid models are the way of the future! Check out the Duncan Lab's ovarian somatic organoid model that was highlighted in this exciting News Feature in Nature on the power of reproductive organoids!
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Dr. Duncan was thrilled to be in Suzhou, China attending the Cold Spring Harbor Asia meeting on Stem Cells, Rejuvenation, and Aging. She shared brand new data on how we can harness new mechanisms of ovarian aging for therapeutic potential!
September 17, 2025 at 9:10 PM
Dr. Duncan was thrilled to be in Suzhou, China attending the Cold Spring Harbor Asia meeting on Stem Cells, Rejuvenation, and Aging. She shared brand new data on how we can harness new mechanisms of ovarian aging for therapeutic potential!
Members of the Duncan Lab participated in the 19th Annual Lewis Landsberg Research Day held at NU. Dylan Hakken was shortlisted as a finalist for the Best Poster award in the Basic Science Research category.
Read more about the presentations: labs.feinberg.northwestern.edu/duncan/news/...
Read more about the presentations: labs.feinberg.northwestern.edu/duncan/news/...
September 12, 2025 at 7:52 PM
Members of the Duncan Lab participated in the 19th Annual Lewis Landsberg Research Day held at NU. Dylan Hakken was shortlisted as a finalist for the Best Poster award in the Basic Science Research category.
Read more about the presentations: labs.feinberg.northwestern.edu/duncan/news/...
Read more about the presentations: labs.feinberg.northwestern.edu/duncan/news/...
Congratulations to Dr. Francesca Duncan and Dr. Hannes Campo on receiving an R03 award for their project "Improving egg quality through an engineered biomimetic follicular microenvironment."
September 3, 2025 at 8:06 PM
Congratulations to Dr. Francesca Duncan and Dr. Hannes Campo on receiving an R03 award for their project "Improving egg quality through an engineered biomimetic follicular microenvironment."
Congratulations to Prianka Hashim on receiving an F31 award for her project "Active surveillance of oocyte quality is moderated by the cGAS-STING pathway."
September 2, 2025 at 8:50 PM
Congratulations to Prianka Hashim on receiving an F31 award for her project "Active surveillance of oocyte quality is moderated by the cGAS-STING pathway."
Dr. Duncan recently participated in a webinar on "Women’s health: insights in research and inclusion," presented by Chemistry World.
If you missed the live event, check out the recording: www.chemistryworld.com/webinars/wom...
If you missed the live event, check out the recording: www.chemistryworld.com/webinars/wom...
Women’s health: insights in research and inclusion
Learn about the history and importance of the gender gap currently impacting women's health sciences
www.chemistryworld.com
August 29, 2025 at 3:41 PM
Dr. Duncan recently participated in a webinar on "Women’s health: insights in research and inclusion," presented by Chemistry World.
If you missed the live event, check out the recording: www.chemistryworld.com/webinars/wom...
If you missed the live event, check out the recording: www.chemistryworld.com/webinars/wom...
Congratulations to Anna Heinrich on receiving a Cornerstone Grant from @histochemicalsoc.bsky.social! This award will support Anna's project “Functional and histological analysis of ovarian tissue from the South African Cheetah."
www.histochemicalsociety.org/2025-corners...
www.histochemicalsociety.org/2025-corners...
August 26, 2025 at 6:31 PM
Congratulations to Anna Heinrich on receiving a Cornerstone Grant from @histochemicalsoc.bsky.social! This award will support Anna's project “Functional and histological analysis of ovarian tissue from the South African Cheetah."
www.histochemicalsociety.org/2025-corners...
www.histochemicalsociety.org/2025-corners...
Reposted by NU Duncan Lab
Dr. Francesca Duncan will speak on this virtual webinar on "Women’s health: insights in research and inclusion"
Learn more and register for the event on August 28!
www.chemistryworld.com/webinars/wom...
Learn more and register for the event on August 28!
www.chemistryworld.com/webinars/wom...
Women’s health: insights in research and inclusion
Learn about the history and importance of the gender gap currently impacting women's health sciences - Join us on 28 August
www.chemistryworld.com
August 22, 2025 at 1:08 PM
Dr. Francesca Duncan will speak on this virtual webinar on "Women’s health: insights in research and inclusion"
Learn more and register for the event on August 28!
www.chemistryworld.com/webinars/wom...
Learn more and register for the event on August 28!
www.chemistryworld.com/webinars/wom...
Reposted by NU Duncan Lab
Investigators led by Francesca Duncan, PhD, @nuduncanlab.bsky.social, have discovered new molecular mechanisms that lead specialized immune cells to cause ovarian aging and functional decline, per a recent study in @plosbiology.org. news.feinberg.northwestern.edu/2025/07/21/n... #healthspan
New Molecular Mechanisms of Ovarian Aging Discovered - News Center
Investigators led by Francesca Elizabeth Duncan, PhD, have discovered new molecular mechanisms that enable specialized immune cells to cause ovarian aging and functional decline, according to a recent...
news.feinberg.northwestern.edu
July 21, 2025 at 3:42 PM
Investigators led by Francesca Duncan, PhD, @nuduncanlab.bsky.social, have discovered new molecular mechanisms that lead specialized immune cells to cause ovarian aging and functional decline, per a recent study in @plosbiology.org. news.feinberg.northwestern.edu/2025/07/21/n... #healthspan
New Publication!
Congratulations to Caroline Kratka and her collaborators on their manuscript which interrogates ovulation in the mouse at high spatiotemporal resolution!
journals.plos.org/plosbiology/...
Congratulations to Caroline Kratka and her collaborators on their manuscript which interrogates ovulation in the mouse at high spatiotemporal resolution!
journals.plos.org/plosbiology/...
Single-cell and spatiotemporal profile of ovulation in the mouse ovary
Ovulation is a complex process that is tightly controlled in a spatiotemporal manner, but the precise mechanisms remain unclear. This study reports single-cell and spatial transcriptomics in mouse ova...
journals.plos.org
July 11, 2025 at 12:23 PM
New Publication!
Congratulations to Caroline Kratka and her collaborators on their manuscript which interrogates ovulation in the mouse at high spatiotemporal resolution!
journals.plos.org/plosbiology/...
Congratulations to Caroline Kratka and her collaborators on their manuscript which interrogates ovulation in the mouse at high spatiotemporal resolution!
journals.plos.org/plosbiology/...
New Publication!
Congrats to Dr. Aubrey Converse on her manuscript which uses innovative approaches to define the transcriptomic signature of ovarian multinucleated giant cells and provide novel insight into the role of this cell population in ovarian aging!
journals.plos.org/plosbiology/...
Congrats to Dr. Aubrey Converse on her manuscript which uses innovative approaches to define the transcriptomic signature of ovarian multinucleated giant cells and provide novel insight into the role of this cell population in ovarian aging!
journals.plos.org/plosbiology/...
Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures
Ovarian multinucleated giant cells are a unique macrophage population that arise within the aging mammalian ovary. This study characterizes their transcriptome in mice, uncovering a potential role in ...
journals.plos.org
July 10, 2025 at 2:23 PM
New Publication!
Congrats to Dr. Aubrey Converse on her manuscript which uses innovative approaches to define the transcriptomic signature of ovarian multinucleated giant cells and provide novel insight into the role of this cell population in ovarian aging!
journals.plos.org/plosbiology/...
Congrats to Dr. Aubrey Converse on her manuscript which uses innovative approaches to define the transcriptomic signature of ovarian multinucleated giant cells and provide novel insight into the role of this cell population in ovarian aging!
journals.plos.org/plosbiology/...
Congratulations to Caroline Kratka on her manuscript which interrogates ovulation in the mouse at high spatiotemporal resolution! This work features single cell and spatial datasets which will be a tremendous resource to the field!
Learn more: engineering.dartmouth.edu/news/dartmou...
Learn more: engineering.dartmouth.edu/news/dartmou...
Dartmouth-Led Study Advances Understanding of Ovulation for…
A new study has for the first time revealed the details of ovulation at the single-cell level which can pave the way not only for the discovery of novel…
engineering.dartmouth.edu
July 8, 2025 at 6:35 PM
Congratulations to Caroline Kratka on her manuscript which interrogates ovulation in the mouse at high spatiotemporal resolution! This work features single cell and spatial datasets which will be a tremendous resource to the field!
Learn more: engineering.dartmouth.edu/news/dartmou...
Learn more: engineering.dartmouth.edu/news/dartmou...
Reposted by NU Duncan Lab
Dr. Francesca Duncan and Dr. Kara Goldman were featured in this USA Today on ovarian aging and reproductive longevity!
www.usatoday.com/story/graphi...
www.usatoday.com/story/graphi...
Beyond fertility and menopause: See why the ovary is central to women’s health and longevity
See why the ovary − often reduced to its reproductive role − menopause, age and estrogen affect a woman’s health throughout her body and lifetime.
www.usatoday.com
June 30, 2025 at 3:03 PM
Dr. Francesca Duncan and Dr. Kara Goldman were featured in this USA Today on ovarian aging and reproductive longevity!
www.usatoday.com/story/graphi...
www.usatoday.com/story/graphi...
Dr. Duncan was featured in this USA Today article about ovarian aging! Check it out!
www.usatoday.com/story/graphi...
www.usatoday.com/story/graphi...
Beyond fertility and menopause: See why the ovary is central to women’s health and longevity
See why the ovary − often reduced to its reproductive role − menopause, age and estrogen affect a woman’s health throughout her body and lifetime.
www.usatoday.com
June 30, 2025 at 2:43 PM
Dr. Duncan was featured in this USA Today article about ovarian aging! Check it out!
www.usatoday.com/story/graphi...
www.usatoday.com/story/graphi...
Tomorrow‼️‼️
Register today for the first SPARK panel, "Human Biospecimen Repositories Fueling Translational Reproductive Science and Medicine Research"
Learn about panelist Dr. Toni Frolova's research: bit.ly/4l5JmfJ
Register: www.upsquad.com/event/regist...
Register today for the first SPARK panel, "Human Biospecimen Repositories Fueling Translational Reproductive Science and Medicine Research"
Learn about panelist Dr. Toni Frolova's research: bit.ly/4l5JmfJ
Register: www.upsquad.com/event/regist...
June 24, 2025 at 2:56 PM
Tomorrow‼️‼️
Register today for the first SPARK panel, "Human Biospecimen Repositories Fueling Translational Reproductive Science and Medicine Research"
Learn about panelist Dr. Toni Frolova's research: bit.ly/4l5JmfJ
Register: www.upsquad.com/event/regist...
Register today for the first SPARK panel, "Human Biospecimen Repositories Fueling Translational Reproductive Science and Medicine Research"
Learn about panelist Dr. Toni Frolova's research: bit.ly/4l5JmfJ
Register: www.upsquad.com/event/regist...
Congratulations to Lauren Haky for passing her qualifying exam and being an official PhD candidate in the Duncan Lab!
June 23, 2025 at 2:23 PM
Congratulations to Lauren Haky for passing her qualifying exam and being an official PhD candidate in the Duncan Lab!
We are very proud of Dylan for receiving the Marcia L. Storch Scholarship for Undergraduate Students!
Dylan is working on a project developing a vascularized microfluidic model of ovarian aging to evaluate non-hormonal contraceptives.
Dylan is working on a project developing a vascularized microfluidic model of ovarian aging to evaluate non-hormonal contraceptives.
Congratulations to Dylan Hakken on receiving the Marcia L. Storch Scholarship!
Dylan is conducting research in the @nuduncanlab.bsky.social under the mentorship of Dr. Hannes Campo!
Dylan is conducting research in the @nuduncanlab.bsky.social under the mentorship of Dr. Hannes Campo!
June 20, 2025 at 2:59 PM
We are very proud of Dylan for receiving the Marcia L. Storch Scholarship for Undergraduate Students!
Dylan is working on a project developing a vascularized microfluidic model of ovarian aging to evaluate non-hormonal contraceptives.
Dylan is working on a project developing a vascularized microfluidic model of ovarian aging to evaluate non-hormonal contraceptives.
Congratulations to Maddie Perry on graduating from the MS-RSM program! Maddie's primary thesis mentor was Dr. Aubrey Converse. We are so proud of Maddie and all she has accomplished during her time in the Duncan Lab! 🎓🎉
June 18, 2025 at 6:45 PM
Congratulations to Maddie Perry on graduating from the MS-RSM program! Maddie's primary thesis mentor was Dr. Aubrey Converse. We are so proud of Maddie and all she has accomplished during her time in the Duncan Lab! 🎓🎉
Many congratulations to Dr. Emily Zaniker-Gomez, PhD, on receiving her degree from the Driskill Graduate Program in Life Sciences!
June 17, 2025 at 9:31 PM
Many congratulations to Dr. Emily Zaniker-Gomez, PhD, on receiving her degree from the Driskill Graduate Program in Life Sciences!
New Duncan Lab publication!
Congratulations to Pooja Devrukhkar along with her co-first authors (Mark Watson and Bikem Soygur) on their manuscript defining and mapping an induced cellular senescence signature in the post-menopausal human ovary!
onlinelibrary.wiley.com/doi/10.1111/...
Congratulations to Pooja Devrukhkar along with her co-first authors (Mark Watson and Bikem Soygur) on their manuscript defining and mapping an induced cellular senescence signature in the post-menopausal human ovary!
onlinelibrary.wiley.com/doi/10.1111/...
A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin-free medium. Single nuclei sequencing and prote...
onlinelibrary.wiley.com
June 17, 2025 at 2:55 PM
New Duncan Lab publication!
Congratulations to Pooja Devrukhkar along with her co-first authors (Mark Watson and Bikem Soygur) on their manuscript defining and mapping an induced cellular senescence signature in the post-menopausal human ovary!
onlinelibrary.wiley.com/doi/10.1111/...
Congratulations to Pooja Devrukhkar along with her co-first authors (Mark Watson and Bikem Soygur) on their manuscript defining and mapping an induced cellular senescence signature in the post-menopausal human ovary!
onlinelibrary.wiley.com/doi/10.1111/...