natasha vs. limbic system
nordicme.bsky.social
natasha vs. limbic system
@nordicme.bsky.social
just me being me
я не смотрела аниме в средней и старшей школе и теперь ощущаю, как не хватает пласта чувственности(?). почему-то уверена, что именно аниме бинжвотчинг меня спасет

26-го последний экзамен, и я накачаю в поезд всякого
June 22, 2025 at 11:27 AM
Reposted by natasha vs. limbic system
Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects!
www.biorxiv.org/content/10.1...
FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets
Linear mixed-effects (LME) models are commonly used for analyzing longitudinal data. However, most applications of LME models rely on random intercepts or simple, e.g., stationary, covariance. Here, w...
www.biorxiv.org
May 16, 2025 at 3:22 PM
Reposted by natasha vs. limbic system
Happy to share our new study on genetic & environmental contributors to age-related decline in ~100K UK Biobank participants!

Here, we used simulation work + longitudinal GWAS and downstream analyses to explore risks involved in cognitive/physical decline
(1/)🧵🧵

shorturl.at/99gqL
Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline - Nature Communications
Large-scale genomic studies focusing on the genetic contribution to human aging have mostly relied on cross-sectional data. With the release of longitudinally curated aging phenotypes by the UK Bioban...
shorturl.at
May 19, 2025 at 12:29 PM