The nlmixr2 group is excited that we are joining the R Consortium as a working group!

I am grateful for the R community and nlmixr2 community and team members that has made this possible.

Join me in celebrating this major milestone in nlmixr2 development history!

blog.nlmixr2.org/blog/2025-11...

This month, I'm excited to introduce two new estimation methods in nlmixr2: Laplace (laplace) and adaptive Gaussian Quadrature (agq).

blog.nlmixr2.org/blog/2025-10...

We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08...

The nlmixr2 team is thrilled to announce the release of nlmixr2 4.0!

This major update introduces the WNL linear compartment solutions, replacing the previous ADVAN-based approach for improved accuracy, stability, and compatibility.

blog.nlmixr2.org/blog/2025-07...

nlmixr2 has an ecosystem around it from researchers and scientists around the world! We celebrate the pharmcometrics community and nlmixr2 community by pointing out integrations between nlmixr2 packages in pharmacometrics.

Come join the development!

blog.nlmixr2.org/blog/2025-06...

Do you want to do pharmacometrics with neural network ODEs? You can use nlmixr2 as well as other tools. See this month's blog post:

blog.nlmixr2.org/blog/2025-04...

#rstats #nlmixr2