Niranjan Nagarajan
@niranjantw.bsky.social
Computational Biologist and Microbiome Scientist at the National University of Singapore
Thank you - bluesky feels like a mirror world :)
April 30, 2025 at 12:26 AM
Thank you - bluesky feels like a mirror world :)
5. Exciting days ahead as we try to decipher the contributions of diverse factors that shape skin microbiome dermotypes, and in turn their influence on skin health! @cherrychengchenli.bsky.social
April 28, 2025 at 4:58 AM
5. Exciting days ahead as we try to decipher the contributions of diverse factors that shape skin microbiome dermotypes, and in turn their influence on skin health! @cherrychengchenli.bsky.social
4. Dermotypes exhibit distinct associations w/ host, where ethnicity and gender play a role in some cases, while others are linked to skincare behaviors. Skin sensitivity, itch and eczema may be affected by dermotype function, highlighting utility for patient stratification & therapeutics
April 28, 2025 at 4:57 AM
4. Dermotypes exhibit distinct associations w/ host, where ethnicity and gender play a role in some cases, while others are linked to skincare behaviors. Skin sensitivity, itch and eczema may be affected by dermotype function, highlighting utility for patient stratification & therapeutics
3. Microbes behave very differently across dermotypes in terms of who they co-occur with! We can confirm this with culture-based experiments that show that oxygen gradients and nutrient availability likely shape why we see distinct dermotypes in various individuals.
@atVidu
@atVidu
April 28, 2025 at 4:56 AM
3. Microbes behave very differently across dermotypes in terms of who they co-occur with! We can confirm this with culture-based experiments that show that oxygen gradients and nutrient availability likely shape why we see distinct dermotypes in various individuals.
@atVidu
@atVidu
2. Dermotypes are highly coordinated across sites. For some sites, we can predict the dermotype just by knowing dermotype of another site. Left and right sides of the body are also highly correlated, suggesting that individual intrinsic factors strongly shape the skin microbiome.
April 28, 2025 at 4:56 AM
2. Dermotypes are highly coordinated across sites. For some sites, we can predict the dermotype just by knowing dermotype of another site. Left and right sides of the body are also highly correlated, suggesting that individual intrinsic factors strongly shape the skin microbiome.
Many exciting results to follow-up on!
1. The skin microbiome has unique “types” in every site - we call them dermotypes. The underarm has as many as 5 distinct ones defined by diverse microbes. We built ML classifiers to predict them w/ near-perfect accuracy with 5 species!
1. The skin microbiome has unique “types” in every site - we call them dermotypes. The underarm has as many as 5 distinct ones defined by diverse microbes. We built ML classifiers to predict them w/ near-perfect accuracy with 5 species!
April 28, 2025 at 4:54 AM
Many exciting results to follow-up on!
1. The skin microbiome has unique “types” in every site - we call them dermotypes. The underarm has as many as 5 distinct ones defined by diverse microbes. We built ML classifiers to predict them w/ near-perfect accuracy with 5 species!
1. The skin microbiome has unique “types” in every site - we call them dermotypes. The underarm has as many as 5 distinct ones defined by diverse microbes. We built ML classifiers to predict them w/ near-perfect accuracy with 5 species!