Herman Nikolayevskiy
@nikolab.bsky.social
Organic Chemist, USF Professor, Education Enthusiast
Have you come across Yang's synthesis of lingzhiol? Looks like they had a similarly rough time with a late stage benzylic oxidation and settled on a radical halogenation/subst./ox. sequence.
www.nature.com/articles/nco...
www.nature.com/articles/nco...
Asymmetric total synthesis of (−)-lingzhiol via a Rh-catalysed [3+2] cycloaddition - Nature Communications
Bicyclic rings with quaternary bridgehead positions are difficult targets, yet are frequently observed in nature. Here, the authors report a cycloaddition reaction giving access to these structures in...
www.nature.com
December 1, 2024 at 6:19 AM
Have you come across Yang's synthesis of lingzhiol? Looks like they had a similarly rough time with a late stage benzylic oxidation and settled on a radical halogenation/subst./ox. sequence.
www.nature.com/articles/nco...
www.nature.com/articles/nco...
Love the science art! Do you have a site where you post your other works?
November 15, 2024 at 3:55 AM
Love the science art! Do you have a site where you post your other works?
I would love to be included as well.
a puppy is standing on the floor with the words pick me written on it .
ALT: a puppy is standing on the floor with the words pick me written on it .
media.tenor.com
November 15, 2024 at 3:52 AM
I would love to be included as well.
Can't unhear it now.
November 14, 2024 at 3:57 AM
Can't unhear it now.
What a beautiful venue! Looks like the fish get to enjoy some sparkly Christmas decorations.
November 14, 2024 at 3:51 AM
What a beautiful venue! Looks like the fish get to enjoy some sparkly Christmas decorations.