Nikki Link
@nikkilink.bsky.social
Fly neuro and disease. Assistant professor. Department of neurobiology. University of Utah.
Congrats Nicole and all contributing authors!
July 10, 2025 at 3:49 PM
Congrats Nicole and all contributing authors!
Human SNW1 can rescue loss of fly Bx42. We are now testing variants to determine how they cause microcephaly.
July 10, 2025 at 3:49 PM
Human SNW1 can rescue loss of fly Bx42. We are now testing variants to determine how they cause microcephaly.
New neurodevelopmental disorder gene SNW1/Bx42. In flies, we show that loss of Bx42 causes reduced brain size and reduced numbers of neural stem cells that divide less.
July 10, 2025 at 3:49 PM
New neurodevelopmental disorder gene SNW1/Bx42. In flies, we show that loss of Bx42 causes reduced brain size and reduced numbers of neural stem cells that divide less.
Read more here: www.newswise.com/articles/two....
Two Brain Proteins are Key to Preventing Seizures, Research in Flies Suggests | Newswise
One in ten people will have a seizure in their life, but treatments remain limited, in part due to incomplete understanding of the brain mechanisms involved. Now, research in fruit flies has uncovered...
www.newswise.com
April 25, 2025 at 5:43 PM
Read more here: www.newswise.com/articles/two....
We found that Imp binds Syndecan RNA. Expression of Syndecan in an animal with reduced Imp rescued adult seizure phenotypes. So, Imp regulates Syndecan to promote neural development and function.
April 25, 2025 at 5:43 PM
We found that Imp binds Syndecan RNA. Expression of Syndecan in an animal with reduced Imp rescued adult seizure phenotypes. So, Imp regulates Syndecan to promote neural development and function.
Since Imp binds RNAs, we wanted to know the neuronal target of Imp that contributes to seizure behavior.
April 25, 2025 at 5:43 PM
Since Imp binds RNAs, we wanted to know the neuronal target of Imp that contributes to seizure behavior.
Developmental Imp played a large role in adult seizure behavior since inhibition of neuronal Imp only during developmental stages had nearly the same effect as continuous neuronal knockdown.
April 25, 2025 at 5:43 PM
Developmental Imp played a large role in adult seizure behavior since inhibition of neuronal Imp only during developmental stages had nearly the same effect as continuous neuronal knockdown.
We studied the RNA binding protein Imp in neurons and found loss of Imp is associated with increased seizures in adults.
April 25, 2025 at 5:43 PM
We studied the RNA binding protein Imp in neurons and found loss of Imp is associated with increased seizures in adults.