nielsbds.bsky.social
@nielsbds.bsky.social
Congrats to Laetitia Coassolo and the @svenssonlab.bsky.social for releasing this story, describing a pipeline for peptide discovery and a new anti-obesity peptide named BRP in @nature.com today. Super happy that I was able to contribute to this work!
www.nature.com/articles/s41...
Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide - Nature
Computational drug discovery is used to identify a 12-mer peptide derived from BRINP2 with potent anti-obesity effects that are independent of leptin, glucagon-like peptide 1 receptor and melanocortin...
www.nature.com
March 5, 2025 at 9:46 PM
We recently published a paper on the use of AlphaFold2 for deorphanizing ligands to single-pass receptors. It turned out we also made the cover and an editorial!

www.cell.com/cms/asset/58...
www.cell.com/cell-systems...
www.cell.com/cell-systems...
www.cell.com
November 27, 2024 at 9:37 PM