Nicole Messina
banner
nicolemessina.bsky.social
Nicole Messina
@nicolemessina.bsky.social
Immunologist interested in immunoregulation, vaccines, paediatric immunology and disease risk. #TB #ID #ImmunoSky

https://www.mcri.edu.au/researcher-details/nicole-messina
February 4, 2025 at 5:33 AM
📚 Our findings, along with our earlier study showing that #BCGvaccine increased risk of symptomatic [but not severe] #COVID-19, suggest that BCG vaccination does not enhance immunity to #SARSCoV2 or COVID-19 vaccines 🌍✨ #IDsky #Immunosky www.sciencedirect.com/science/arti...
BCG vaccination of healthcare workers for protection against COVID-19: 12-month outcomes from an international randomised controlled trial
Bacille Calmette-Guérin (BCG) vaccine has immunomodulatory effects that may provide protection against unrelated infectious diseases. We aimed to dete…
www.sciencedirect.com
February 4, 2025 at 5:33 AM
💉 After two doses of adenovirus-based or mRNA-based #COVID vaccine, cytokine and adaptive immune responses to #SARSCoV2 were similar between the #BCGvaccine and Control groups indicating that the specific effects of #COVID19 vaccines overcame the immunomodulatory effects of BCG. 💪
February 4, 2025 at 5:33 AM
🔬 Before #COVID-19 vaccination (almost a year after randomisation), healthcare workers who received #BCGVaccine had reduced cytokine responses to #SARSCoV2 compared to controls, indicating BCG-induced immunomodulation.
February 4, 2025 at 5:33 AM
Reposted by Nicole Messina

A paper of Firsts for me: rdcu.be/d2gBV
- 1st #StrepA paper
- 1st for my lab (started in 2023).
- 1st senior authorship

📣 Shout out to my amazing co-1st authors @joshosowicki.bsky.social & Hannah Frost.
📣 Andrew Steer & Nikki Moreland for leading this work with me + all other co-authors not on 🦋
Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections
Nature Communications - Streptococcus pyogenes is a deadly bacteria without a vaccine. Here, researchers measured antibodies in serum and saliva from a strep throat human challenge trial. Baseline...
rdcu.be
December 3, 2024 at 1:11 PM
Hi Rod, it's great seeing the community rebuild on blue sky. Would love to be added to your immunology starter packs.
November 29, 2024 at 10:41 PM