Niclas Decker
@niclas-decker.bsky.social
Recent graduate in Molecular Bioengineering (MSc), TU Dresden | Formerly in #lipidomics research at Fedorova Lab | Exploring new opportunities in bioengineering and life sciences
(1) Macrocycles allowed for spectacular advances in difficult-to-drug protein–protein interactions in recent years. Cyclic peptides are at the forefront, facilitated by their comparable ease to synthesise and amenability to screening using mRNA display.
November 22, 2024 at 1:27 AM
(1) Macrocycles allowed for spectacular advances in difficult-to-drug protein–protein interactions in recent years. Cyclic peptides are at the forefront, facilitated by their comparable ease to synthesise and amenability to screening using mRNA display.
Future text book example for functional stress granules! G3BP1 granule formation being pH-dependent could explain observations of stress granules as protective plugs at endolysosomal membrane damage site - indicating it might be exclusively applicable to membrane damage in lysosomes though
Stress granules plug and stabilize damaged endolysosomal membranes - Nature
Stress granules function at sites of intracellular membrane damage by forming on and stabilizing the ruptured membrane and promoting membrane repair.
www.nature.com
November 29, 2023 at 4:08 AM
Future text book example for functional stress granules! G3BP1 granule formation being pH-dependent could explain observations of stress granules as protective plugs at endolysosomal membrane damage site - indicating it might be exclusively applicable to membrane damage in lysosomes though
What is life, anyway?
A New Theory for the Assembly of Life in the Universe | Quanta Magazine
If we want to understand complex constructions, such as ourselves, assembly theory says we must account for the entire history of how such entities came to be.
www.quantamagazine.org
November 26, 2023 at 5:41 PM
What is life, anyway?