Nick Polizzi
@nickpolizzi.bsky.social
Asst prof at HMS, PI at DFCI
Designing proteins
polizzilab.org
Designing proteins
polizzilab.org
Congrats, Gabe! Interesting re: arg. Mutating surface lys —> arg also is known to help w crystallization. Wonder if related 🤔
November 19, 2025 at 9:42 PM
Congrats, Gabe! Interesting re: arg. Mutating surface lys —> arg also is known to help w crystallization. Wonder if related 🤔
Congrats, Chris!
November 18, 2025 at 4:46 PM
Congrats, Chris!
Heartbreaking. So sorry to hear this, Willow
October 31, 2025 at 1:25 PM
Heartbreaking. So sorry to hear this, Willow
There are several depending on what you want to use it for. LASErMPNN and ligandMPNN can both output rotamers given an input seq. I have more experience with LASEr, which is pretty fast, easy to use for this purpose, and relatively lightweight
September 18, 2025 at 5:04 PM
There are several depending on what you want to use it for. LASErMPNN and ligandMPNN can both output rotamers given an input seq. I have more experience with LASEr, which is pretty fast, easy to use for this purpose, and relatively lightweight
Congrats, Daniel! 🥳 Def worth a celebratory Mcflurry🍦
September 2, 2025 at 3:49 PM
Congrats, Daniel! 🥳 Def worth a celebratory Mcflurry🍦
Hats off (or on, rather!) to you and Birte and team!
July 29, 2025 at 8:58 PM
Hats off (or on, rather!) to you and Birte and team!