Nick Collins
nick-collins11.bsky.social
Nick Collins
@nick-collins11.bsky.social
Assistant Professor at Weill Cornell Medicine studying the impact of diet and the microbiota on our immune system
Reposted by Nick Collins
Our work co-led by @scripps.edu students Dominic & Jonathan shows that microbial tropism determines how metabolites are presented to #MAIT cells!
MAIT cell responses to intracellular and extracellular pathogens are mediated by distinct antigen presenting cells https://www.biorxiv.org/content/10.1101/2025.05.03.652000v1
May 9, 2025 at 4:59 AM
Reposted by Nick Collins
Excited to share our preprint demonstrating how fumarate metabolism by host and pathogen promotes pneumonia! Itaconate synergizes with fumarate, driving staphylococcal adaptation for survival. Check it out!👇
www.biorxiv.org/content/10.1...
Regulation of airway fumarate by host and pathogen promotes S. aureus pneumonia
Staphylococcus aureus is a leading cause of healthcare-associated pneumonia, contributing significantly to morbidity and mortality worldwide. As a ubiquitous colonizer of the upper respiratory tract, ...
www.biorxiv.org
April 19, 2025 at 3:42 PM
A nice write-up on our recent collaborative study, led by the lab of Chun-Jun Guo at Weill Cornell

news.weill.cornell.edu/news/2025/04...
Gut Microbes Release Cancer-fighting Bile Acids that Block Hormone Signals
Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking ...
news.weill.cornell.edu
April 18, 2025 at 3:22 PM
We are hiring a research technician!

This position will be critical to advance our understanding of how diet and the microbiota can enhance our immune system against infections and cancer.

If you are interested, please reach out for more information!
January 12, 2025 at 9:58 PM