NICE replaced the "End of Life" modifier with "severity" in 2022. What has been the experience of using severity weights in NICE Technology Appraisals?

👉Read about the project, report and paper here: bit.ly/4rQFX8d

Registration is open for the next virtual NICE DSU masterclass - Methods for mapping health utilities for NICE submissions. @ABPI on 3rd and 4th November 2025. @NICEComms /@NICE_DSU /@ABPI_UK
More details: bit.ly/4omxBTx

Registration is open for the next in-person NICE DSU masterclass - Methods for the analysis of non-randomised, patient level data for the estimation of treatment effects. @ABPI on 2nd October 2025. @NICEComms /@NICE_DSU /@ABPI_UK 
More details: bit.ly/4gABul7
Future masterclases: bit.ly/42tbEd1

Check out our one page summary for the latest TSD:

TSD 27: Prioritising Studies and Outcomes for NICE HealthTech Literature Reviews.

This TSD outlines approaches to further narrow or widen inclusion: buff.ly/YMKqpHb

NEW TSD: Prioritising Studies and Outcomes for NICE HealthTech Literature Reviews.

Reviews of clinical effectiveness can vary widely in the volume/type of available evidence.

This TSD outlines approaches to further narrow or widen inclusion: buff.ly/YMKqpHb

Check out our one page summary for the latest TSD:
TSD 26: Expert elicitation for long-term survival outcomes on the TSd one page summary page, here: www.sheffield.ac.uk/nice-dsu/tsd...

Registration is now open for the next NICE DSU masterclass - Optimising NICE submissions in oncology. This is an in-person event being held by the @ABPI on 12th June 2025. @NICEComms /@NICE_DSU /@ABPI_UK
More details: bit.ly/4iEVWjU
Future masterclases: bit.ly/3Ym8IwK

The newly released TSD26 Expert Elicitation for assessing long-term survival outcomes is now available on the DSU website. Complete details and a dossier template can be accessed here: bit.ly/42QmMjp

NEW TSD 25 evidence synthesis one page summary. To view visit: bit.ly/3ZxIreu

To view the series of TSDs in the area of evidence synthesis, visit: bit.ly/3ZsV8XX

For all available TSD one page summaries, visit: bit.ly/3Sx5ljz

A summary of projects undertaken in respect of NHS waiting times for elective surgery by EEPRU and @eshcru can be found here:-https://bit.ly/3VAk4eV

For full details of the project, reports and publications, see here:- bit.ly/3VyI0iG

NEW TSD25 Evidence synthesis of diagnostic test accuracy for decision making. Covers: implementing bivariate/HSROC model & meta-analysis across explicit thresholds (with a focus on Bayesian estimation), using results in a decision model, inc estimating the optimal threshold.

Registration for the next online masterclass on the 4th & 5th Nov is now open - Methods for mapping health utilities for NICE submissions:-
bit.ly/3Nvy05I

NICE replaced the cost effectiveness modifier for “End-of-Life” with one for “Severity” in 2022 but there are concerns that severity is not being used as often as expected. New DSU report investigates this issue, using information from more than 500 Technology Appraisal decisions bit.ly/3zsQ3WI