Nguyet Le
@nguyetle.bsky.social
PhD candidate in the Blackshaw Lab @ Johns Hopkins Medicine
Reposted by Nguyet Le
Our latest manuscript on glia-to-neuron conversion in retina is out in @elife.bsky.social. We show that AAV-mediated overexpression of Oct4 induces glia-to-bipolar cell conversion in wildtype retina, and that this is greatly enhanced by loss of function of Rbpj.
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
elifesciences.org
April 5, 2025 at 2:59 PM
Our latest manuscript on glia-to-neuron conversion in retina is out in @elife.bsky.social. We show that AAV-mediated overexpression of Oct4 induces glia-to-bipolar cell conversion in wildtype retina, and that this is greatly enhanced by loss of function of Rbpj.
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...