Noel Morgan
ngmorgan.bsky.social
Noel Morgan
@ngmorgan.bsky.social
Emeritus Professor - Islet Biology Group (IBEx) University of Exeter
Reposted by Noel Morgan
Our new research article 🔬 suggests that the maturity of the pancreas at onset of type 1 diabetes may hold the key to understanding why the disease course differs in early vs later life 📈. Watch our video to learn more! Produced in collaboration with @amanigardner.bsky.social

youtu.be/O-Q0e5rEUy4
Small things matter in Type 1 diabetes
YouTube video by University of Exeter
youtu.be
November 13, 2025 at 10:39 AM
Reposted by Noel Morgan
📚 Or check out our new research article, recently released in Science Advances 🔗: doi.org/10.1126/scia...
Small things matter: Lack of extraislet β cells in type 1 diabetes
Early loss of small extraislet β cells in children with type 1 diabetes could explain age-related differences in disease.
doi.org
November 13, 2025 at 10:39 AM
Reposted by Noel Morgan
Up front and free to read in our May issue #editorspicks: Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes link.springer.com/article/10.1...
Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia
Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...
link.springer.com
May 14, 2025 at 5:41 PM
Reposted by Noel Morgan
Excited to announce our latest collaborative work on type 1 diabetes with @pialeete.bsky.social, @ngmorgan.bsky.social, and Nicolás Verschueren van Rees: tinyurl.com/3ste3px9

We combine large section staining and machine learning to show that the mantle-core structure is conserved in human islets.
Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia
Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...
tinyurl.com
March 3, 2025 at 1:47 PM
Reposted by Noel Morgan
Hugely excited to share a truly cross-disciplinary project examining human #islet_architecture in health&in #type_1_diabetes #T1D: combining #machine_learning, elegant #mathematical_modelling in whole section, fixed pancreatic samples stained for all 5 islet hormones:
1/2
🧪🔬🚀
doi.org/10.1007/s001...
Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia
Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...
doi.org
February 27, 2025 at 2:49 PM