7/ The whole-brain functional connectivity features were highly idiosyncratic, as they were comprised of individual-specific intra- and inter-network pairings (e.g. 2 individuals shown)

6/ Idiographic predictive models were successful, providing strong evidence that dynamic connectivity at “rest” reflects spontaneous cognition when personalized brain-experience mappings are considered

4/ But beyond default network, the large-scale networks most strongly associated with mind-wandering were largely unique in each individual (possibly reflecting different mind-wandering content)

3/ We used precision functional mapping to isolate default networks A and B (DN-A and DN-B) and found positive correlations between mind-wandering and DN-A activation within all 3 individuals

2/ Three densely sampled individuals each responded to hundreds of thought probes while undergoing “resting state” fMRI (simple visual fixation) and reported mind-wandering episodes >60% of the time

1/ New paper and first real foray into “precision fMRI”: Individual variability in neural representations of mind-wandering direct.mit.edu/netn/article...