@nazifasalsabeel.bsky.social
Doctoral Candidate, Icahn School of Medicine at Mount Sinai
Reposted
OUT NOW: Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers | Science Advances www.science.org/doi/10.1126/... #SawyersLab #MSKCC @mskcancercenter.bsky.social
Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers
Restoration of downstream mTOR signaling causes resistance to combined Akt and androgen receptor blockade in prostate cancer.
www.science.org
February 20, 2025 at 8:39 PM
OUT NOW: Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers | Science Advances www.science.org/doi/10.1126/... #SawyersLab #MSKCC @mskcancercenter.bsky.social
Reposted
OUT NOW: ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L rdcu.be/eEVKR @mskcancercenter.bsky.social @natureportfolio.nature.com #SawyersLabMSKCC
ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L
Nature Genetics - Lineage tracing in mice identifies a subpopulation of basal cells that express Tmprss2 and Nkx3 as the origin of ERG-driven prostate cancer. Upon expansion, these cells show an...
rdcu.be
September 8, 2025 at 3:38 PM
OUT NOW: ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L rdcu.be/eEVKR @mskcancercenter.bsky.social @natureportfolio.nature.com #SawyersLabMSKCC