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This article in the November issue discusses the changing landscape of medicinal chemistry optimization based on analysis of sets of hits, leads and drug candidates, which reveals shifts in key physicochemical properties
rdcu.be/ePoB9
www.nature.com/articles/s41...
rdcu.be/ePoB9
www.nature.com/articles/s41...
The changing landscape of medicinal chemistry optimization
Nature Reviews Drug Discovery - Medicinal chemistry optimizations in the progression from hit to lead to drug candidate affect properties of small-molecule drugs such as their molecular weight and...
rdcu.be
November 11, 2025 at 3:23 PM
This article in the November issue discusses the changing landscape of medicinal chemistry optimization based on analysis of sets of hits, leads and drug candidates, which reveals shifts in key physicochemical properties
rdcu.be/ePoB9
www.nature.com/articles/s41...
rdcu.be/ePoB9
www.nature.com/articles/s41...