Natalia Brzozowska
@nataliabrzozowska.bsky.social
Researching somatic evolution in liver disease at Wellcome Sanger Institute
Pinned
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency - Nature Genetics
The expansion of clones with distinct SERPINA1 somatic mutants in the livers of alpha-1 antitrypsin deficiency (A1AT) patients is consistent with convergent evolution. These variants interfere with th...
www.nature.com
Excited to share our new preprint demonstrating somatic rescue mutations in a genetic liver disease! [1/12]
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Excited to share our new preprint demonstrating somatic rescue mutations in a genetic liver disease! [1/12]
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency - Nature Genetics
The expansion of clones with distinct SERPINA1 somatic mutants in the livers of alpha-1 antitrypsin deficiency (A1AT) patients is consistent with convergent evolution. These variants interfere with th...
www.nature.com
March 12, 2025 at 5:29 PM
Excited to share our new preprint demonstrating somatic rescue mutations in a genetic liver disease! [1/12]
www.nature.com/articles/s41...
www.nature.com/articles/s41...