Louis Ates
@mycolates.bsky.social
Tuberculosis, immunology and microbiology. The PPE-guy. Preclinical lead TB vaccine development at BioNTech. Activity here strictly personal.
Reposted by Louis Ates
I presented our preclinical work on the BNT164 #Tuberculosis candidates. This work is now also available as a preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well-tolerated and efficacious in rodent models
We designed and preclinically tested two mRNA-LNP-based vaccine candidates to protect against tuberculosis (TB). BNT164a1 and BNT164b1 encode the same eight Mycobacterium tuberculosis ( Mtb ) antigens...
www.biorxiv.org
November 12, 2025 at 12:54 PM
I presented our preclinical work on the BNT164 #Tuberculosis candidates. This work is now also available as a preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
I presented our preclinical work on the BNT164 #Tuberculosis candidates. This work is now also available as a preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well-tolerated and efficacious in rodent models
We designed and preclinically tested two mRNA-LNP-based vaccine candidates to protect against tuberculosis (TB). BNT164a1 and BNT164b1 encode the same eight Mycobacterium tuberculosis ( Mtb ) antigens...
www.biorxiv.org
November 12, 2025 at 12:54 PM
I presented our preclinical work on the BNT164 #Tuberculosis candidates. This work is now also available as a preprint!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Louis Ates
I realise the link did not work. Here is the correct link: journals.asm.org/doi/10.1128/...
A multiplex Mtb-specific FluoroSpot assay measuring IFNγ, IL-2, and TNF-secreting cells can improve accuracy and differentiation across the tuberculosis spectrum | Journal of Clinical Microbiology
Accurate diagnosis of Mycobacterium tuberculosis (Mtb) infection remains a cornerstone in tuberculosis (TB) control. Current interferon-gamma
release assays (IGRAs) lack the ability to distinguish bet...
journals.asm.org
October 30, 2025 at 7:10 AM
I realise the link did not work. Here is the correct link: journals.asm.org/doi/10.1128/...
a man in a suit says shots fired
ALT: a man in a suit says shots fired
media.tenor.com
October 23, 2025 at 11:23 AM
Excellent pictogram use though.
October 23, 2025 at 11:11 AM
Excellent pictogram use though.
Uitstekende luis in de pels :)
October 22, 2025 at 7:40 AM
Uitstekende luis in de pels :)
Would you say it is a T-bet?
October 6, 2025 at 8:11 PM
Would you say it is a T-bet?
However, it also nicely illustrates that higher is not always better. Lovely paper.
September 30, 2025 at 7:37 PM
However, it also nicely illustrates that higher is not always better. Lovely paper.
Thanks for an old-fashioned SciTwitter thread Joachim! Groetjes.
September 29, 2025 at 7:29 PM
Thanks for an old-fashioned SciTwitter thread Joachim! Groetjes.
I can't seem to find any TB genes in that link. Am I doing it wrong?
September 28, 2025 at 8:07 AM
I can't seem to find any TB genes in that link. Am I doing it wrong?