Marcos Vieira
@mvieira.bsky.social
Computational Research Scientist at the Cobey Lab at the University of Chicago, studying the ecology and evolution of pathogens and the immune system
cobeylab.uchicago.edu/people/marcos
cobeylab.uchicago.edu/people/marcos
Reposted by Marcos Vieira
Sang Woo (Daniel) Park and I are excited to share a new preprint, "Susceptible host dynamics explain pathogen resilience to perturbations" [1/8]
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 23, 2025 at 9:07 PM
Sang Woo (Daniel) Park and I are excited to share a new preprint, "Susceptible host dynamics explain pathogen resilience to perturbations" [1/8]
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Marcos Vieira
Today @natmedicine.bsky.social published our study showing the older individuals born prior to 1968 have more antibodies that cross-react to #H5N1 relative to younger individuals. If H5N1 causes a pandemic, children will likely be the most susceptible. 1/2
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Immune history shapes human antibody responses to H5N1 influenza viruses - Nature Medicine
H5N1 strain-specific antibodies are higher in older individuals and correlate more with birth year than with age, suggesting that younger individuals are potentially more likely to benefit from H5N1 v...
www.nature.com
March 13, 2025 at 5:39 PM
Today @natmedicine.bsky.social published our study showing the older individuals born prior to 1968 have more antibodies that cross-react to #H5N1 relative to younger individuals. If H5N1 causes a pandemic, children will likely be the most susceptible. 1/2
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Marcos Vieira
Artigo liderado por @portellatp.bsky.social www.sciencedirect.com/science/arti...
Bayesian spatio-temporal modeling to assess the effect of land-use changes on the incidence of Cutaneous Leishmaniasis in the Brazilian Amazon
Cutaneous Leishmaniasis (CL) is a vector-borne disease caused by a protozoan of the genus Leishmania and is considered one of the most important negle…
www.sciencedirect.com
September 15, 2024 at 12:15 AM
Artigo liderado por @portellatp.bsky.social www.sciencedirect.com/science/arti...
Reposted by Marcos Vieira
Seems population immunity should be useful for forecasting flu, right? Using cross-sectional, age-representative neutralizing titers measured in the summer of 2017 in Philly, we find that the clade to which we infer the greatest susceptibility dominated the next season. Even more, we found...
Measures of population immunity can predict the dominant clade of influenza A (H3N2) and reveal age-associated differences in susceptibility and specificity https://www.medrxiv.org/content/10.1101/2023.10.26.23297569v1
Measures of population immunity can predict the dominant clade of influenza A (H3N2) and reveal age-associated differences in susceptibility and specificity https://www.medrxiv.org/content/10.1101/2023.10.26.23297569v1
For antigenically variable pathogens such as influenza, strain fitness is partly determined by the r
www.medrxiv.org
October 27, 2023 at 4:06 PM
Seems population immunity should be useful for forecasting flu, right? Using cross-sectional, age-representative neutralizing titers measured in the summer of 2017 in Philly, we find that the clade to which we infer the greatest susceptibility dominated the next season. Even more, we found...
Antibodies are the product of evolution on two timescales: over millions of years in vertebrate populations, and within weeks of infection or vaccination in populations of B cells. We ask how those timescales interact in our paper out in Plos Pathogens 🧵 1/n t.co/vRdGYYQwsU
Germline-encoded specificities and the predictability of the B cell response
Author summary Antibodies arise as B cell receptors encoded by the stochastic recombination of immunoglobulin genes. While those genes evolve over millions of years, the receptors themselves evolve wi...
t.co
September 5, 2023 at 10:36 PM
Antibodies are the product of evolution on two timescales: over millions of years in vertebrate populations, and within weeks of infection or vaccination in populations of B cells. We ask how those timescales interact in our paper out in Plos Pathogens 🧵 1/n t.co/vRdGYYQwsU