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mueller-lab.bsky.social
MüllerLab
@mueller-lab.bsky.social
130 followers 110 following 12 posts
The MüllerLab is a research group @uni-muenster.de interested in Bioinorganic Chemistry with a particular focus on nucleic acids.
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mueller-lab.bsky.social
Excited to share our study "Are i-Motif Structures in DNA Compatible with Cytosine–Ag(I)–Cytosine Base Pairs?" in @angewandtechemie.bsky.social 🧬

Congrats to Vicky and thanks to Miguel Galindo, Bernie Kraatz and everyone else involved for this collaboration 🎉

🔎Check it out: doi.org/10.1002/anie...
Are i‐Motif Structures in DNA Compatible with Cytosine–Ag(I)–Cytosine Base Pairs?
An i-motif/duplex junction was evaluated with respect to its ability to replace the protons from the hemi-protonated C:CH+ pairs by AgI ions to form C–AgI–C base pairs. Interestingly, only one such m...
doi.org
November 24, 2025 at 2:31 PM
Reposted by MüllerLab
chempharmms.bsky.social
Open doors for future chemists, food chemists, and pharmacists: More than 900 guests explored our labs and lecture halls at the yearly University day @uni-muenster.de .
Photos: Valerie Hollwedel, Hauke Engler
A high school student holding a large methane flame in her open hand. Prof. Denise Steiner informs high school students about drug production in a lecture hall. In the biochemistry lab, Bianca Berkenfeld explains to 7 high school students how to do a bacteria streak. Two PhD-students prepare ice cream using liquid nitrogen. Beneath a blue sky outside, the working desk is covered with fog from water condensing from the cooled air.
November 14, 2025 at 10:02 AM
mueller-lab.bsky.social
Congrats to our freshly minted Dr. Mai 🎉

Expert in DNA synthesis, master of ImPhen and now off to new adventures 🧬 We’ll miss him after some fantastic years, all the best for your future!
October 10, 2025 at 2:43 PM
mueller-lab.bsky.social
Team outing with the work group - great weather, great vibes and even a round of golf with a surprisingly solid performance on the course 😉⛳️
September 15, 2025 at 12:20 PM
mueller-lab.bsky.social
Congrats to Florian on his publication investigating 5-fluorouracil in metal-mediated base pairing🥳 Check it out: doi.org/10.1016/j.ji... 🧬
Redirecting
doi.org
September 1, 2025 at 10:24 AM
mueller-lab.bsky.social
What an honor for Carla to present her research at the Ph.D. graduation ceremony. Well deserved and well done! Now it's time to celebrate Tabea and Carla 🥳
July 12, 2025 at 12:20 PM
mueller-lab.bsky.social
Proud supervisors today as Tabea successfully defended her Ph.D. thesis. Congrats Dr. Lenz and all the best for your future 🚀🔥
July 4, 2025 at 12:31 PM
mueller-lab.bsky.social
Congratulations to Carla for successfully defending her thesis today!🥳

Thank you for an amazing time and all the best for your future, Dr. Bardehle!
June 13, 2025 at 3:24 PM
mueller-lab.bsky.social
Lumos! Carla developed a magic wand promoting lanthanoid ion luminescence in DNA duplexes 🧙‍♀️

Check out the cover image @ChemistryEurope (doi.org/10.1002/ceur...) 🥳

#OpenAccess
Lumos: A β‐Diketone‐Derived Artificial Nucleobase Forming Inter‐Strand Complexes in DNA that Promote Lanthanoid Ion Luminescence
The Cover Feature shows a parallel-stranded DNA duplex with a terminally attached luminescent lanthanoid complex, represented by a magic wand that lights up when the corresponding spell is cast. The ....
doi.org
May 16, 2025 at 9:49 AM
mueller-lab.bsky.social
We are excited to share the publication of our latest work in JBIC! 🥳 This study sheds light on how silver ions interact with canonical nucleic acids, using advanced NMR spectroscopy.

🔗  rdcu.be/ekuNi

Congratulations to Tabea and the entire team 🇩🇪🇸🇮
Determination of silver(I)-binding sites in canonical B-DNA by NMR spectroscopy
rdcu.be
May 5, 2025 at 10:51 AM
mueller-lab.bsky.social
Want to learn more about water-soluble luminescent platinum(II) complexes for guanine quadruplex binding? Check out the full paper of this collaborative Müller/Strassert work @daltontrans.rsc.org (doi.org/10.1039/D4DT...)

Congrats to Simon, Marian, Alex, Marcus, Joschua and Ali 🎉
Water-soluble luminescent platinum(II) complexes for guanine quadruplex binding
A family of 16 platinum(ii) complexes was synthesized with the aim of obtaining water-soluble luminescent coordination compounds for guanine quadruplex (G4) binding. The complexes share a common tride...
pubs.rsc.org
March 26, 2025 at 10:56 AM
mueller-lab.bsky.social
👏🏽Congrats Carla, on publishing your first paper this year! 🎉 This study explores metal-mediated base pairing with cobalt, nickel, zinc, and even lanthanoids to tune duplex stability, paving the way for new applications in DNA chemistry!

📄Read more: dx.doi.org/10.1002/chem...
Tuning the Duplex Stability of DNA Oligonucleotides Containing Metal‐Mediated Base Pairs of Imidazole‐Derived Nucleobases
The formation of metal-mediated base pairs comprised of HQIm (3H-imidazo[4,5-f]quinolin-5-ol) and/or CaIm (imidazole-4-carboxylate) induces a significant thermal stabilization of DNA with the 3d meta....
dx.doi.org
March 11, 2025 at 1:54 PM
mueller-lab.bsky.social
We're excited to announce the launch of our new Bluesky account @mueller-lab.bsky.social 🎉 Along with this, we're thrilled to welcome our new PhD students Nele, Julian, Luca and Rafael! Stay tuned for updates and insights from our team! 🚀👨🏽‍🔬👩🏼‍🔬
February 21, 2025 at 11:11 AM