MTBI
@mtbi.bsky.social
Manhiça Tuberculosis Initiative.
Working towards improving TB control through the development of new diagnostic tools, treatments & vaccines.
We are a team based in between Barcelona at @isglobal.org and Manhiça @manhica_cism
Working towards improving TB control through the development of new diagnostic tools, treatments & vaccines.
We are a team based in between Barcelona at @isglobal.org and Manhiça @manhica_cism
During World Science Day for Peace and Development, Dr. Dinis Nguenha from CISM shared that using the #Truenat portable molecular diagnostic system enabled 82% of TB patients to start treatment on the same day of diagnosis, improving care and reducing delays!
November 12, 2025 at 2:11 PM
During World Science Day for Peace and Development, Dr. Dinis Nguenha from CISM shared that using the #Truenat portable molecular diagnostic system enabled 82% of TB patients to start treatment on the same day of diagnosis, improving care and reducing delays!
🗨️ Our PhD student, Salome Valencia, presented today at the XXIX Jornadas Internacionales sobre Tuberculosis 2025, hosted by #CoMB, #uiTB & #fuiTB. She explored how armed conflict and social inequality shape #TB in Colombia. Grateful to all for fostering these vital discussions!
November 11, 2025 at 2:26 PM
TB isn’t a disease of the past — it’s still one of the world’s top infectious killers (WHO, 2024).
❌ Not limited to certain countries
❌ A positive test ≠ contagious
✅ TB is curable, but stigma + myths slow progress.
#Tuberculosis #GlobalHealth
❌ Not limited to certain countries
❌ A positive test ≠ contagious
✅ TB is curable, but stigma + myths slow progress.
#Tuberculosis #GlobalHealth
November 10, 2025 at 2:19 PM
TB isn’t a disease of the past — it’s still one of the world’s top infectious killers (WHO, 2024).
❌ Not limited to certain countries
❌ A positive test ≠ contagious
✅ TB is curable, but stigma + myths slow progress.
#Tuberculosis #GlobalHealth
❌ Not limited to certain countries
❌ A positive test ≠ contagious
✅ TB is curable, but stigma + myths slow progress.
#Tuberculosis #GlobalHealth
From new WHO guidance on TB & diabetes to innovations workshops, climate frameworks, and global commitments, 2025 is a pivotal year in the fight to #EndTB. Progress is happening, but action must continue. 🩺
#GlobalHealth
#GlobalHealth
October 28, 2025 at 9:55 AM
From new WHO guidance on TB & diabetes to innovations workshops, climate frameworks, and global commitments, 2025 is a pivotal year in the fight to #EndTB. Progress is happening, but action must continue. 🩺
#GlobalHealth
#GlobalHealth
New meta-analysis finds no clear mortality benefit from intensified treatment regimens (ie. high-dose rifampicin, fluoroquinolones) for #tuberculous #meningitis in adults. More consistent, high-quality trials needed. 📚 pubmed.ncbi.nlm.nih.gov/41064692/
Intensified Treatment of Tuberculous Meningitis in Adults: A Systematic Review and Meta-analysis - PubMed
Current clinical trial evidence does not support the use of intensified TBM treatment in adults. However, these analyses are limited by diverse TBM case definitions, absence of MRC grading at enrollme...
pubmed.ncbi.nlm.nih.gov
October 15, 2025 at 12:36 PM
New meta-analysis finds no clear mortality benefit from intensified treatment regimens (ie. high-dose rifampicin, fluoroquinolones) for #tuberculous #meningitis in adults. More consistent, high-quality trials needed. 📚 pubmed.ncbi.nlm.nih.gov/41064692/
New study in PLOS ONE analyzes 255 messages between TB patients & treatment supporters using digital adherence tech (DATs).
Beyond reminders, patients need empathy, support & better usability.
📖 pubmed.ncbi.nlm.nih.gov/40705794/
#TB #mHealth #DigitalHealth
Beyond reminders, patients need empathy, support & better usability.
📖 pubmed.ncbi.nlm.nih.gov/40705794/
#TB #mHealth #DigitalHealth
Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement - PubMed
This study highlights the importance of personalized, empathetic communication, and reliable technology to enhance the effectiveness of DATs. Future DAT solutions should prioritize technological relia...
pubmed.ncbi.nlm.nih.gov
October 10, 2025 at 2:38 PM
New study in PLOS ONE analyzes 255 messages between TB patients & treatment supporters using digital adherence tech (DATs).
Beyond reminders, patients need empathy, support & better usability.
📖 pubmed.ncbi.nlm.nih.gov/40705794/
#TB #mHealth #DigitalHealth
Beyond reminders, patients need empathy, support & better usability.
📖 pubmed.ncbi.nlm.nih.gov/40705794/
#TB #mHealth #DigitalHealth
🩺New study compares 4R10 vs 2R20 regimens for latent TB. No major cost difference, but meds + follow-ups are biggest drivers. Fewer visits could cut costs, depending on setting.
🔗 pubmed.ncbi.nlm.nih.gov/40980570/
#TB #TPT #GlobalHealth #PublicHealth
🔗 pubmed.ncbi.nlm.nih.gov/40980570/
#TB #TPT #GlobalHealth #PublicHealth
Costs of 4 Months of Rifampin Versus 2 Months of Double-dose Rifampin for Tuberculosis Infection: Post-Hoc Analysis of a Phase 2b Randomized Trial - PubMed
Most costs associated with TPT are due to medications and the baseline treatment initiation visit. TPT regimens requiring fewer follow-up visits may reduce overall cost, but the magnitude of this redu...
pubmed.ncbi.nlm.nih.gov
October 9, 2025 at 11:44 AM
🩺New study compares 4R10 vs 2R20 regimens for latent TB. No major cost difference, but meds + follow-ups are biggest drivers. Fewer visits could cut costs, depending on setting.
🔗 pubmed.ncbi.nlm.nih.gov/40980570/
#TB #TPT #GlobalHealth #PublicHealth
🔗 pubmed.ncbi.nlm.nih.gov/40980570/
#TB #TPT #GlobalHealth #PublicHealth
🧬 TB remains one of the world’s top infectious killers.
Where, in your opinion, should innovation funding go next?
🟦 Diagnostics
🟦 Shorter treatments
🟦 Vaccines
🟦 Health systems
🌐 Read the WHO Global TB Report 2024: www.who.int/teams/global...
#TB #GlobalHealth #InfectiousDiseases #WHO
Where, in your opinion, should innovation funding go next?
🟦 Diagnostics
🟦 Shorter treatments
🟦 Vaccines
🟦 Health systems
🌐 Read the WHO Global TB Report 2024: www.who.int/teams/global...
#TB #GlobalHealth #InfectiousDiseases #WHO
Global Tuberculosis Report 2024
Global Tuberculosis Report 2024
www.who.int
October 7, 2025 at 1:40 PM
🧬 TB remains one of the world’s top infectious killers.
Where, in your opinion, should innovation funding go next?
🟦 Diagnostics
🟦 Shorter treatments
🟦 Vaccines
🟦 Health systems
🌐 Read the WHO Global TB Report 2024: www.who.int/teams/global...
#TB #GlobalHealth #InfectiousDiseases #WHO
Where, in your opinion, should innovation funding go next?
🟦 Diagnostics
🟦 Shorter treatments
🟦 Vaccines
🟦 Health systems
🌐 Read the WHO Global TB Report 2024: www.who.int/teams/global...
#TB #GlobalHealth #InfectiousDiseases #WHO
🩺 WHO now recommends a 6-month all-oral regimen for drug-resistant TB: shorter, safer, and easier to complete. A major step forward in global TB care.
📄 Full update: www.who.int/news/item/15...
#TB #GlobalHealth
📄 Full update: www.who.int/news/item/15...
#TB #GlobalHealth
WHO announces landmark changes in treatment of drug-resistant tuberculosis
The World Health Organization (WHO) today released its Consolidated guidelines on tuberculosis (TB)- Module 4: treatment and care, consolidating all previous guidelines into a single comprehensive doc...
www.who.int
October 1, 2025 at 1:34 PM
🩺 WHO now recommends a 6-month all-oral regimen for drug-resistant TB: shorter, safer, and easier to complete. A major step forward in global TB care.
📄 Full update: www.who.int/news/item/15...
#TB #GlobalHealth
📄 Full update: www.who.int/news/item/15...
#TB #GlobalHealth
🧠 UN: Children face a “new era of crisis.” For TB, this means more gaps in #care, fragile systems, and kids left behind. We can’t end #TB without reaching the most vulnerable.
🔗 news.un.org/en/story/202...
#EndTB #ChildHealth #GlobalHealth
🔗 news.un.org/en/story/202...
#EndTB #ChildHealth #GlobalHealth
Funding cuts jeopardise global fight against tuberculosis, WHO warns
The UN World Health Organization (WHO) warned on Wednesday that severe funding cuts – particularly in the United States – are threatening decades of progress in the fight against tuberculosis (TB), st...
news.un.org
September 30, 2025 at 11:23 AM
🧠 UN: Children face a “new era of crisis.” For TB, this means more gaps in #care, fragile systems, and kids left behind. We can’t end #TB without reaching the most vulnerable.
🔗 news.un.org/en/story/202...
#EndTB #ChildHealth #GlobalHealth
🔗 news.un.org/en/story/202...
#EndTB #ChildHealth #GlobalHealth
❤️ On #WorldHeartDay, a reminder: #TB can affect more than lungs, it can influence hearts.
New research shows 1 in 5 patients with tuberculous pericarditis develop deadly heart failure post-surgery. Early care matters.
🔗 www.sciencedirect.com/science/arti...
#EndTB #HeartHealth
New research shows 1 in 5 patients with tuberculous pericarditis develop deadly heart failure post-surgery. Early care matters.
🔗 www.sciencedirect.com/science/arti...
#EndTB #HeartHealth
Analysis of risk factors of low cardiac output syndrome after pericardiectomy for tuberculous constrictive pericarditis: A retrospective study
Low cardiac output syndrome (LCOS) is the leading cause of death after cardiac surgery. Studies have shown that 24% of postoperative mortality in pati…
www.sciencedirect.com
September 29, 2025 at 9:20 AM
❤️ On #WorldHeartDay, a reminder: #TB can affect more than lungs, it can influence hearts.
New research shows 1 in 5 patients with tuberculous pericarditis develop deadly heart failure post-surgery. Early care matters.
🔗 www.sciencedirect.com/science/arti...
#EndTB #HeartHealth
New research shows 1 in 5 patients with tuberculous pericarditis develop deadly heart failure post-surgery. Early care matters.
🔗 www.sciencedirect.com/science/arti...
#EndTB #HeartHealth
🩺 New Lancet study: Men are ~1.7x more likely than women to be infected w/ #TB due to biology and gendered factors.
Question for you: How can we design TB strategies that reflect real sex & gender differences without oversimplifying?
🔗 www.thelancet.com/journals/lan...
#GlobalHealth #HealthEquity
Question for you: How can we design TB strategies that reflect real sex & gender differences without oversimplifying?
🔗 www.thelancet.com/journals/lan...
#GlobalHealth #HealthEquity
Sex differences in the risk of Mycobacterium tuberculosis infection: a systematic review and meta-analysis of population-based immunoreactivity surveys
Men have higher M tuberculosis immunoreactivity risk than women, which is likely to
be a key driver of the sex differences in global tuberculosis morbidity and mortality.
This difference could be due ...
www.thelancet.com
September 25, 2025 at 11:51 AM
🩺 New Lancet study: Men are ~1.7x more likely than women to be infected w/ #TB due to biology and gendered factors.
Question for you: How can we design TB strategies that reflect real sex & gender differences without oversimplifying?
🔗 www.thelancet.com/journals/lan...
#GlobalHealth #HealthEquity
Question for you: How can we design TB strategies that reflect real sex & gender differences without oversimplifying?
🔗 www.thelancet.com/journals/lan...
#GlobalHealth #HealthEquity
New NEJM study shows 3 oral, 9-month regimens are noninferior for rifampin-resistant #TB. A win for patient-centered care + policy updates.
🔗 www.nejm.org/doi/full/10....
#TB #GlobalHealth #HealthPolicy #InfectiousDisease
🔗 www.nejm.org/doi/full/10....
#TB #GlobalHealth #HealthPolicy #InfectiousDisease
www.nejm.org
September 18, 2025 at 8:48 AM
New NEJM study shows 3 oral, 9-month regimens are noninferior for rifampin-resistant #TB. A win for patient-centered care + policy updates.
🔗 www.nejm.org/doi/full/10....
#TB #GlobalHealth #HealthPolicy #InfectiousDisease
🔗 www.nejm.org/doi/full/10....
#TB #GlobalHealth #HealthPolicy #InfectiousDisease
🧠Rethinking TB care: Integration isn’t a burden; it’s a cost-effective, people-centred strategy. A new @thelancet.com article makes the case for linking #TB, lung health & shared risks.
🔗 www.thelancet.com/journals/lan...
#Tuberculosis #LungHealth #GlobalHealth #PublicHealth #TheLancet
🔗 www.thelancet.com/journals/lan...
#Tuberculosis #LungHealth #GlobalHealth #PublicHealth #TheLancet
Integrated care for tuberculosis and lung health
In 2023, tuberculosis claimed approximately 1·3 million lives,1 providing a stark
reminder of the persistent inequities and widening gaps in access to tuberculosis
services and care worldwide. Tubercu...
www.thelancet.com
September 16, 2025 at 8:42 AM
🧠Rethinking TB care: Integration isn’t a burden; it’s a cost-effective, people-centred strategy. A new @thelancet.com article makes the case for linking #TB, lung health & shared risks.
🔗 www.thelancet.com/journals/lan...
#Tuberculosis #LungHealth #GlobalHealth #PublicHealth #TheLancet
🔗 www.thelancet.com/journals/lan...
#Tuberculosis #LungHealth #GlobalHealth #PublicHealth #TheLancet
🧪 New stool #qPCR test improves pediatric #TB detection in high-burden settings! It's #non-invasive, has a high specificity, and improves pediatric TB detection where sputum or gastric sample collection is challenging.
🔗 academic.oup.com/jpids/articl...
#PediatricTB #GlobalHealth #Diagnostics
🔗 academic.oup.com/jpids/articl...
#PediatricTB #GlobalHealth #Diagnostics
Performance of a Novel Stool Quantitative Polymerase Chain Reaction Assay for Pediatric Tuberculosis Detection in Sub-Saharan Africa
AbstractBackground. Children have paucibacillary tuberculosis and cannot provide expectorated sputum. Invasive specimen collection, by gastric aspiration o
academic.oup.com
September 9, 2025 at 11:53 AM
🧪 New stool #qPCR test improves pediatric #TB detection in high-burden settings! It's #non-invasive, has a high specificity, and improves pediatric TB detection where sputum or gastric sample collection is challenging.
🔗 academic.oup.com/jpids/articl...
#PediatricTB #GlobalHealth #Diagnostics
🔗 academic.oup.com/jpids/articl...
#PediatricTB #GlobalHealth #Diagnostics
Reposted by MTBI
Good food is part of the fight against TB . Let’s make nutrition a priority for everyone on treatment! #EndTB youtu.be/VYQOKK7wIjI
Good food fights TB . Nutrition should be part of every treatment! #endtb
YouTube video by TB Proof
youtu.be
September 8, 2025 at 8:02 AM
Good food is part of the fight against TB . Let’s make nutrition a priority for everyone on treatment! #EndTB youtu.be/VYQOKK7wIjI
🚨 Exciting global health opportunity!
@isglobal.org is hiring a Medical Research Fellow (Tuberculosis) in Manhiça, Mozambique.
Lead impactful TB research with a top team.
🩺 MD + 4yrs clinical exp
🗓️ 2-yr contract
🔗 Apply: jobs.isglobal.org/jobs/6376227
#GlobalHealth #TB #ResearchJobs #PublicHealth
@isglobal.org is hiring a Medical Research Fellow (Tuberculosis) in Manhiça, Mozambique.
Lead impactful TB research with a top team.
🩺 MD + 4yrs clinical exp
🗓️ 2-yr contract
🔗 Apply: jobs.isglobal.org/jobs/6376227
#GlobalHealth #TB #ResearchJobs #PublicHealth
Medical Research Fellow, Area of Tuberculosis - Barcelona Institute for Global Health (ISGlobal)
The Barcelona Institute for Global Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education. ISGlobal has a b...
jobs.isglobal.org
September 5, 2025 at 11:12 AM
🚨 Exciting global health opportunity!
@isglobal.org is hiring a Medical Research Fellow (Tuberculosis) in Manhiça, Mozambique.
Lead impactful TB research with a top team.
🩺 MD + 4yrs clinical exp
🗓️ 2-yr contract
🔗 Apply: jobs.isglobal.org/jobs/6376227
#GlobalHealth #TB #ResearchJobs #PublicHealth
@isglobal.org is hiring a Medical Research Fellow (Tuberculosis) in Manhiça, Mozambique.
Lead impactful TB research with a top team.
🩺 MD + 4yrs clinical exp
🗓️ 2-yr contract
🔗 Apply: jobs.isglobal.org/jobs/6376227
#GlobalHealth #TB #ResearchJobs #PublicHealth
🔍 New MTBI-led study shows gaps in #TB awareness in #Mozambique particularly among adults w/ #HIV and caregivers of children.
🛑 Low TB knowledge
⚠️ Stigma
🚫 Gender barriers
Call for community-driven interventions.
📖 journals.plos.org/globalpublic...
#GlobalHealth #PublicHealth #HealthEquity
🛑 Low TB knowledge
⚠️ Stigma
🚫 Gender barriers
Call for community-driven interventions.
📖 journals.plos.org/globalpublic...
#GlobalHealth #PublicHealth #HealthEquity
Gaps in TB-related knowledge and practices: An assessment of health care seeking behavior among adults with HIV and caregivers of paediatric patients with presumptive TB symptoms in Manhiça district, ...
Although tuberculosis is a preventable and treatable disease, its management has been challenging for tuberculosis control and prevention programs in low- and middle- income countries such as Mozambiq...
journals.plos.org
September 5, 2025 at 8:16 AM
🔍 New MTBI-led study shows gaps in #TB awareness in #Mozambique particularly among adults w/ #HIV and caregivers of children.
🛑 Low TB knowledge
⚠️ Stigma
🚫 Gender barriers
Call for community-driven interventions.
📖 journals.plos.org/globalpublic...
#GlobalHealth #PublicHealth #HealthEquity
🛑 Low TB knowledge
⚠️ Stigma
🚫 Gender barriers
Call for community-driven interventions.
📖 journals.plos.org/globalpublic...
#GlobalHealth #PublicHealth #HealthEquity
🙌🏾Yesterday marked a truly memorable moment! The very first @mtbi.bsky.social Initiative Forum was a resounding success!
🤝It brought together passionate experts and researchers to exchange ideas on #TB prevention & explore exciting developments in vaccine research.
🤝It brought together passionate experts and researchers to exchange ideas on #TB prevention & explore exciting developments in vaccine research.
July 23, 2025 at 9:12 AM
🙌🏾Yesterday marked a truly memorable moment! The very first @mtbi.bsky.social Initiative Forum was a resounding success!
🤝It brought together passionate experts and researchers to exchange ideas on #TB prevention & explore exciting developments in vaccine research.
🤝It brought together passionate experts and researchers to exchange ideas on #TB prevention & explore exciting developments in vaccine research.
The day has arrived! Don’t miss our very first @mtbi.bsky.social Forum today alongside the 4th Manhiça Foundation Global Health Symposium.
➡️ Follow it online: lnkd.in/dbJT_KWG
@isglobal.org @fundacionareces.bsky.social eces.bsky.social
@acesurafrica.bsky.social africa.bsky.social @manhica_cism
➡️ Follow it online: lnkd.in/dbJT_KWG
@isglobal.org @fundacionareces.bsky.social eces.bsky.social
@acesurafrica.bsky.social africa.bsky.social @manhica_cism
July 22, 2025 at 8:33 AM
The day has arrived! Don’t miss our very first @mtbi.bsky.social Forum today alongside the 4th Manhiça Foundation Global Health Symposium.
➡️ Follow it online: lnkd.in/dbJT_KWG
@isglobal.org @fundacionareces.bsky.social eces.bsky.social
@acesurafrica.bsky.social africa.bsky.social @manhica_cism
➡️ Follow it online: lnkd.in/dbJT_KWG
@isglobal.org @fundacionareces.bsky.social eces.bsky.social
@acesurafrica.bsky.social africa.bsky.social @manhica_cism
💥We are delighted to announce that our initiative @mtbi.bsky.social will be hosting its first-ever Forum, taking place alongside the 4th Edition of the Manhiça Foundation Global Health Symposium, on July 22!
📝Register to attend virtually or in person: www.cismmanhica.org/simposio25
📝Register to attend virtually or in person: www.cismmanhica.org/simposio25
July 18, 2025 at 8:51 AM
💥We are delighted to announce that our initiative @mtbi.bsky.social will be hosting its first-ever Forum, taking place alongside the 4th Edition of the Manhiça Foundation Global Health Symposium, on July 22!
📝Register to attend virtually or in person: www.cismmanhica.org/simposio25
📝Register to attend virtually or in person: www.cismmanhica.org/simposio25
Reposted by MTBI
We just published a piece about the participation of people deprived of liberty in #tuberculosis vaccine trials. Should they be protected from research, or through research?
www.thelancet.com/journals/lan...
@thelancetinfdis.bsky.social @isglobal.org @mtbi.bsky.social
www.thelancet.com/journals/lan...
@thelancetinfdis.bsky.social @isglobal.org @mtbi.bsky.social
June 30, 2025 at 11:54 AM
We just published a piece about the participation of people deprived of liberty in #tuberculosis vaccine trials. Should they be protected from research, or through research?
www.thelancet.com/journals/lan...
@thelancetinfdis.bsky.social @isglobal.org @mtbi.bsky.social
www.thelancet.com/journals/lan...
@thelancetinfdis.bsky.social @isglobal.org @mtbi.bsky.social
💥Today we share great news! @agbasteiro.bsky.social has been honored with the XX Banc Sabadell Foundation Award for Biomedical Research! 👏🏾
🔗 fundacionbancosabadell.com/la-fundacion...
#PremiosBiomédicaCiencias #LaCulturadelTalento #Investigación
🔗 fundacionbancosabadell.com/la-fundacion...
#PremiosBiomédicaCiencias #LaCulturadelTalento #Investigación
La Fundación Banco Sabadell premia dos investigadores por sus trabajos sobre la tuberculosis y sobre el diseño computacional de enzimas - Fundación Banco Sabadell
fundacionbancosabadell.com
July 3, 2025 at 9:31 AM
💥Today we share great news! @agbasteiro.bsky.social has been honored with the XX Banc Sabadell Foundation Award for Biomedical Research! 👏🏾
🔗 fundacionbancosabadell.com/la-fundacion...
#PremiosBiomédicaCiencias #LaCulturadelTalento #Investigación
🔗 fundacionbancosabadell.com/la-fundacion...
#PremiosBiomédicaCiencias #LaCulturadelTalento #Investigación
We participated in the European Advanced Course in Clinical Tuberculosis #EACCTB 2025, organized by TBnet.
Our PI @agbasteiro.bsky.social was an invited speaker on the clinical spectrum of TB, contributing to the scientific exchange with his expertise.
#endTB #GlobalHealth #MTBI
Our PI @agbasteiro.bsky.social was an invited speaker on the clinical spectrum of TB, contributing to the scientific exchange with his expertise.
#endTB #GlobalHealth #MTBI
July 2, 2025 at 11:40 AM
We participated in the European Advanced Course in Clinical Tuberculosis #EACCTB 2025, organized by TBnet.
Our PI @agbasteiro.bsky.social was an invited speaker on the clinical spectrum of TB, contributing to the scientific exchange with his expertise.
#endTB #GlobalHealth #MTBI
Our PI @agbasteiro.bsky.social was an invited speaker on the clinical spectrum of TB, contributing to the scientific exchange with his expertise.
#endTB #GlobalHealth #MTBI