Moustafa Algamal
moustafaalgamal.bsky.social
Moustafa Algamal
@moustafaalgamal.bsky.social
Instructor in Neurology MGH and HMS. Dementia and neurodegenerative disorders.
Reposted by Moustafa Algamal
Calling all Boston-based/bound research technicians! Come join a neuroimaging lab looking at cerebrovascular function in CAA! Please share with those who may be interested 🧠 massgeneralbrigham.wd1.myworkdayjobs.com/MGBExternal/...
Research Technician I
Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to adva...
massgeneralbrigham.wd1.myworkdayjobs.com
August 26, 2025 at 6:57 PM
Excited to be attending AAIC 2025 at the Toronto Convention Centre! I’ll be presenting my poster (#188) tomorrow — please stop by and take a look.
July 27, 2025 at 3:43 PM
Reposted by Moustafa Algamal
Happy to share our latest publication on subcellular myelin proteomics and structural changes in Alzheimer disease www.nature.com/articles/s41...
June 14, 2025 at 4:13 PM
Reposted by Moustafa Algamal
Exciting to see growing work on microglial GABA receptors and their role in regulating inhibition. Here, hyperactive inhibitory neurons in epilepsy activate microglia via GABA. Activated microglia then eliminate inhibitory synapses through a GABA–C3 feedback loop. www.nature.com/articles/s41...
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy - Nature Neuroscience
The microglia–neuron interactions contributing to neuronal hyperexcitability are unclear. Here, the authors show how GABA and C3 signaling coordinate microglial engulfment of inhibitory synapses, driv...
www.nature.com
May 31, 2025 at 1:27 PM
Reposted by Moustafa Algamal
It is out! Read how you achieve 1.7 mm deep 3-photon imaging in prefrontal cortex with dendritic spine resolution over a week.
www.nature.com/articles/s42...
Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution - Communications Biology
Three-photon in vivo imaging provides access to medial prefrontal cortex, hippocampus and spinal cord in mice at up to 1.7 mm depth of neurons, dendrites, spines, astrocytes and microglia.
www.nature.com
June 1, 2025 at 9:58 AM