Come back! You are most welcome. Would be the best for all of us, a united Europe

thank you! and we still need to catch up!!!

#immunity #Tcells #mRNA #HuR #smFISH #RNAbiology

Funded by European Research Council (ERC)and Oncode Institute,
Research performed at Sanquin Blood Supply Foundation, in collaboration with the Vrije Universiteit Amsterdam (VU Amsterdam) Amsterdam

She got great help for the data analysis from bioinformaticians (Philipp Savakis, Nikolina Sostaric, and Nandhini Kanagasabesan, and was helped by other labmembers Branka Popović, Leyma Wardak, Antonia Bradarić and Aurélie Guislain.

This was a fantastic collaboration with the Evelina Tutucci lab who taught us all about smFISH in non-adherent cells. And a heroic effort of Maria Valeria Lattanzio, to dared to jump into the deep and who really pulled it off.

We could simultaneously study how cytokine RNAs are transcribed and where mature mRNA goes to when T cells become activated.This method can shed light on as to why in some cases T cells can have really high mRNA levels, yet don't produce any protein (we showcase it for HuR deficiency).

Can we do the same with Farage please? Wilders? (who got a lot of platform by the journalists which in fact made him big... ) At least no more front page headlines. no place for lies there. Lets learn from this.

First cats in the US, and now Swans in the UK?! how absurd can it get...

love it!

#Tcells #RBPs #generegulation preprint

www.biorxiv.org/content/10.1...

Great work spearheaded by Ben @bnicolet.bsky.social

We used information on conservation, length, codon usage, miRNA and RNA Binding Protein and putative Post-translational modificationmotifs +more. Together #RNA abundance, we could predict protein abundance AND modulate protein expression with synthetic 3'UTRs, exemplified in #Tcells