Molpigs
@molpigs.bsky.social
We are the MOLecular Programming Interest Group, early-career researchers in the field of molecular programming building our community through podcasts, reading groups and community activities. Links to all podcast feeds and Slack at molpi.gs
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Molpigs
@molpigs.bsky.social
· Nov 12
We've organized two reading groups on classic papers in molecular programming:
- A celebration of the late Ned Seeman, the founder of DNA nanotechnology
- Foundations of DNA computing
Let's talk about some of the great papers we've read! Each discussion will start as a quote of this post. 🧬
- A celebration of the late Ned Seeman, the founder of DNA nanotechnology
- Foundations of DNA computing
Let's talk about some of the great papers we've read! Each discussion will start as a quote of this post. 🧬
Podcast drop🧬! As part of the Molecular Programming Flightplan, we assembled a panel discussion on collaboration! The panel is now available as two podcasts, each with half the panel, and a bonus interview with @programmablematter.bsky.social.
Links to all major feeds here:
podcast.molpi.gs
Links to all major feeds here:
podcast.molpi.gs
July 16, 2025 at 7:19 PM
Podcast drop🧬! As part of the Molecular Programming Flightplan, we assembled a panel discussion on collaboration! The panel is now available as two podcasts, each with half the panel, and a bonus interview with @programmablematter.bsky.social.
Links to all major feeds here:
podcast.molpi.gs
Links to all major feeds here:
podcast.molpi.gs
Reposted by Molpigs
Molecular Programmers🧬: @programmablematter.bsky.social summons us to organize a “Flightplan”, a 10-year strategic initiative for the field. The meeting will be July 21-23rd in Seattle and will be moderated by NSF program officers. Travel funding is available!
Apply here: mpflightplan.com/apply-now
Apply here: mpflightplan.com/apply-now
Apply now! — MP Decadal Flightplan
mpflightplan.com
June 23, 2025 at 8:12 PM
Molecular Programmers🧬: @programmablematter.bsky.social summons us to organize a “Flightplan”, a 10-year strategic initiative for the field. The meeting will be July 21-23rd in Seattle and will be moderated by NSF program officers. Travel funding is available!
Apply here: mpflightplan.com/apply-now
Apply here: mpflightplan.com/apply-now
Follow WONDER for networking opportunities and upcoming mentorship events aimed at increasing female representation and retention in the Molecular Programming field 🧬
Hello (bluesky) world!
We are WONDER 🧬, an organization aimed at female PhD students, early and late career researchers within DNA Nanotechnology and related fields 😊🧬
Follow us here to stay updated and sign up to our mailing list (link in bio) to never miss out on any news🧬
We are WONDER 🧬, an organization aimed at female PhD students, early and late career researchers within DNA Nanotechnology and related fields 😊🧬
Follow us here to stay updated and sign up to our mailing list (link in bio) to never miss out on any news🧬
May 2, 2025 at 7:39 PM
Follow WONDER for networking opportunities and upcoming mentorship events aimed at increasing female representation and retention in the Molecular Programming field 🧬
Thank you to everybody who came to our 🧬DNA origami🧬 reading group over the last 7 weeks! We all learned a ton from the discussions and revisiting these classic papers.
What should our next topic be?? Leave us a comment to help us decide.
What should our next topic be?? Leave us a comment to help us decide.
April 28, 2025 at 11:23 PM
Thank you to everybody who came to our 🧬DNA origami🧬 reading group over the last 7 weeks! We all learned a ton from the discussions and revisiting these classic papers.
What should our next topic be?? Leave us a comment to help us decide.
What should our next topic be?? Leave us a comment to help us decide.
It's time for the finale of the 🧬DNA origami🧬 reading group! This week we're thinking about how to make origami biiiiiig. When previous papers assembled multiple origami, the yield started to crash. This week's paper is an attempt to get around that problem.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
April 19, 2025 at 3:43 PM
It's time for the finale of the 🧬DNA origami🧬 reading group! This week we're thinking about how to make origami biiiiiig. When previous papers assembled multiple origami, the yield started to crash. This week's paper is an attempt to get around that problem.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
This week in the Molpigs 🧬DNA Origami🧬 Reading Group there are two cool concepts we're exploring: dynamic structures, and using blunt-end stacking as a structural tool instead of treating it as The Enemy. Info on how to join the discussion in the quoted thread!
www.science.org/doi/full/10....
www.science.org/doi/full/10....
April 13, 2025 at 12:44 PM
This week in the Molpigs 🧬DNA Origami🧬 Reading Group there are two cool concepts we're exploring: dynamic structures, and using blunt-end stacking as a structural tool instead of treating it as The Enemy. Info on how to join the discussion in the quoted thread!
www.science.org/doi/full/10....
www.science.org/doi/full/10....
This week in the Molpigs 🧬DNA Origami🧬 Reading Group, we're exploring how DNA origami went from tightly packed sheets/blocks, to open wireframes with complex and beautiful geometries. This paper required designing intricate strand routing, let's follow the path!
www.nature.com/articles/nna...
www.nature.com/articles/nna...
April 6, 2025 at 9:01 PM
This week in the Molpigs 🧬DNA Origami🧬 Reading Group, we're exploring how DNA origami went from tightly packed sheets/blocks, to open wireframes with complex and beautiful geometries. This paper required designing intricate strand routing, let's follow the path!
www.nature.com/articles/nna...
www.nature.com/articles/nna...
Welcome to the halfway point in the 🧬DNA origami🧬 reading group! This week we're reading "Folding DNA into Twisted and Curved Nanoscale Shapes", the second 2009 paper from the Shih lab demonstrating the programmability of DNA origami.
www.science.org/doi/full/10....
www.science.org/doi/full/10....
March 30, 2025 at 10:34 AM
Welcome to the halfway point in the 🧬DNA origami🧬 reading group! This week we're reading "Folding DNA into Twisted and Curved Nanoscale Shapes", the second 2009 paper from the Shih lab demonstrating the programmability of DNA origami.
www.science.org/doi/full/10....
www.science.org/doi/full/10....
For week three of our 🧬DNA origami🧬 reading group we're reading the first of two 2009 papers from the Shih lab which demonstrated that you really could fold DNA into any 3D shape! This paper also demonstrated Cadnano, which remains the most used design software today.
www.nature.com/articles/nat...
www.nature.com/articles/nat...
March 23, 2025 at 9:54 PM
For week three of our 🧬DNA origami🧬 reading group we're reading the first of two 2009 papers from the Shih lab which demonstrated that you really could fold DNA into any 3D shape! This paper also demonstrated Cadnano, which remains the most used design software today.
www.nature.com/articles/nat...
www.nature.com/articles/nat...
The second meeting of the Origami Reading Group is tonight at 18:00 EST! Come discuss the original DNA Origami with us (spoiler, it’s shockingly sassy). 🧬
March 20, 2025 at 11:41 AM
The second meeting of the Origami Reading Group is tonight at 18:00 EST! Come discuss the original DNA Origami with us (spoiler, it’s shockingly sassy). 🧬
It's time to put the origami in our DNA Origami Reading Group! This week we're reading Rothemund's "Folding DNA to create nanoscale shapes and patterns" to understand this seminal paper in context! What did Rothemund know, and what did he intuit? Join us to discuss!🧬
www.nature.com/articles/nat...
www.nature.com/articles/nat...
March 15, 2025 at 10:54 AM
It's time to put the origami in our DNA Origami Reading Group! This week we're reading Rothemund's "Folding DNA to create nanoscale shapes and patterns" to understand this seminal paper in context! What did Rothemund know, and what did he intuit? Join us to discuss!🧬
www.nature.com/articles/nat...
www.nature.com/articles/nat...
First 🧬DNA Origami reading group🧬 meets today! Our first paper is a precursor to origami, where Yan and colleagues showed that you could build larger structures via scaffolded tile assembly!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
March 11, 2025 at 8:15 AM
First 🧬DNA Origami reading group🧬 meets today! Our first paper is a precursor to origami, where Yan and colleagues showed that you could build larger structures via scaffolded tile assembly!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Excited to start our 🧬DNA origami🧬 reading group next week! We’ll be hosting two weekly sessions:
Tuesday @ 20:15 CET
Thursday @ 18 EST
You can still sign up by joining the reading-group channel on Slack or filling the form for email updates!
Timezone converter:
molpi.gs/timezones#tz...
Tuesday @ 20:15 CET
Thursday @ 18 EST
You can still sign up by joining the reading-group channel on Slack or filling the form for email updates!
Timezone converter:
molpi.gs/timezones#tz...
March 8, 2025 at 11:00 AM
Excited to start our 🧬DNA origami🧬 reading group next week! We’ll be hosting two weekly sessions:
Tuesday @ 20:15 CET
Thursday @ 18 EST
You can still sign up by joining the reading-group channel on Slack or filling the form for email updates!
Timezone converter:
molpi.gs/timezones#tz...
Tuesday @ 20:15 CET
Thursday @ 18 EST
You can still sign up by joining the reading-group channel on Slack or filling the form for email updates!
Timezone converter:
molpi.gs/timezones#tz...
It's time for another Molpigs reading group! This time we'll be routing our brains through the history of DNA origami. We will be starting the week of March 10th and reading 1 paper/week for 7 weeks. Please fill out either the form linked in the next post or join the Molpigs Slack for updates. 🧬🧬🧬
March 2, 2025 at 7:13 PM
It's time for another Molpigs reading group! This time we'll be routing our brains through the history of DNA origami. We will be starting the week of March 10th and reading 1 paper/week for 7 weeks. Please fill out either the form linked in the next post or join the Molpigs Slack for updates. 🧬🧬🧬
In this series on the origins of DNA nanotechnology, we've so far seen a lot of DNA, not a lot of nanostructure and not a lot of technology. Today's paper introduces structure, we're looking at the first well-defined object built out of DNA, the humble cube! 🧬 1/8
www.nature.com/articles/350...
www.nature.com/articles/350...
November 25, 2024 at 11:06 PM
In this series on the origins of DNA nanotechnology, we've so far seen a lot of DNA, not a lot of nanostructure and not a lot of technology. Today's paper introduces structure, we're looking at the first well-defined object built out of DNA, the humble cube! 🧬 1/8
www.nature.com/articles/350...
www.nature.com/articles/350...
DNA nanotechnology works because of the specificity of A-T and G-C base-pairs. But isolated pairs aren't stable! Only when you have longer stretches will DNA form a helix. Before finally building the first structure, let's discuss Ned's sequence design tool. 1/6
www.tandfonline.com/doi/pdf/10.1...
www.tandfonline.com/doi/pdf/10.1...
November 21, 2024 at 8:07 PM
DNA nanotechnology works because of the specificity of A-T and G-C base-pairs. But isolated pairs aren't stable! Only when you have longer stretches will DNA form a helix. Before finally building the first structure, let's discuss Ned's sequence design tool. 1/6
www.tandfonline.com/doi/pdf/10.1...
www.tandfonline.com/doi/pdf/10.1...
Paper #3 in our series: the time Ned and co read too much science fiction. That's right, it's Robinson & Seeman's "The design of a biochip: a self-assembling molecular-scale memory device" published in Protein Engineering in 1987. 🧬 1/7
academic.oup.com/peds/article...
academic.oup.com/peds/article...
November 14, 2024 at 8:17 PM
Paper #3 in our series: the time Ned and co read too much science fiction. That's right, it's Robinson & Seeman's "The design of a biochip: a self-assembling molecular-scale memory device" published in Protein Engineering in 1987. 🧬 1/7
academic.oup.com/peds/article...
academic.oup.com/peds/article...
Wake up and smell the acrylamide! Today we're talking about the second paper in our retrospective on Ned Seeman's work, "An immobile nucleic acid junction constructed from oligonucleotides", Nature 1983. 🧬 1/5
www.nature.com/articles/305...
www.nature.com/articles/305...
November 13, 2024 at 9:55 PM
Wake up and smell the acrylamide! Today we're talking about the second paper in our retrospective on Ned Seeman's work, "An immobile nucleic acid junction constructed from oligonucleotides", Nature 1983. 🧬 1/5
www.nature.com/articles/305...
www.nature.com/articles/305...
First up, Ned Seeman's 1982 "Nucleic Acid Junctions and Lattices", published in the Journal of Theoretical Biology. This was the first paper to propose that through sequence design it might be possible to create precisely-defined crystal lattices out of DNA. 🧬
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 12, 2024 at 10:01 PM
First up, Ned Seeman's 1982 "Nucleic Acid Junctions and Lattices", published in the Journal of Theoretical Biology. This was the first paper to propose that through sequence design it might be possible to create precisely-defined crystal lattices out of DNA. 🧬
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
We've organized two reading groups on classic papers in molecular programming:
- A celebration of the late Ned Seeman, the founder of DNA nanotechnology
- Foundations of DNA computing
Let's talk about some of the great papers we've read! Each discussion will start as a quote of this post. 🧬
- A celebration of the late Ned Seeman, the founder of DNA nanotechnology
- Foundations of DNA computing
Let's talk about some of the great papers we've read! Each discussion will start as a quote of this post. 🧬
November 12, 2024 at 9:10 PM
We've organized two reading groups on classic papers in molecular programming:
- A celebration of the late Ned Seeman, the founder of DNA nanotechnology
- Foundations of DNA computing
Let's talk about some of the great papers we've read! Each discussion will start as a quote of this post. 🧬
- A celebration of the late Ned Seeman, the founder of DNA nanotechnology
- Foundations of DNA computing
Let's talk about some of the great papers we've read! Each discussion will start as a quote of this post. 🧬
Reposted by Molpigs
Are there any other scientists from molecular programming here? That's self-assembly, chemical computation, rational design et al. I made a mol pro feed which works like the Science (🧪) feed. Let me know, I add you to the list, you post with a 🧬 emoji. Let's assemble!
bsky.app/profile/flop...
bsky.app/profile/flop...
November 11, 2024 at 9:25 PM
Are there any other scientists from molecular programming here? That's self-assembly, chemical computation, rational design et al. I made a mol pro feed which works like the Science (🧪) feed. Let me know, I add you to the list, you post with a 🧬 emoji. Let's assemble!
bsky.app/profile/flop...
bsky.app/profile/flop...
Goodbye X, hello BlueSky! Let's start rebuilding the molecular programming community over here. If you're curious about what the field is, and who we are, our latest podcast episode is an introduction to our new team members and a lot of geekery about the field. 🧬
podcast.molpi.gs/media/team2-...
podcast.molpi.gs/media/team2-...
molpigs Podcast | molpigs TeamMolecular Programming Interest Grouptilibit nanosystems
podcast.molpi.gs
November 11, 2024 at 9:14 PM
Goodbye X, hello BlueSky! Let's start rebuilding the molecular programming community over here. If you're curious about what the field is, and who we are, our latest podcast episode is an introduction to our new team members and a lot of geekery about the field. 🧬
podcast.molpi.gs/media/team2-...
podcast.molpi.gs/media/team2-...