Manuel Molano-Mazón
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molanomazon.bsky.social
Manuel Molano-Mazón
@molanomazon.bsky.social
Neuroscientist. I work at the Universitat Politècnica de Catalunya (Barcelona). I like RNNs, decision making, sequential biases, evolution.
9/ And all the data is here:
osf.io/794vk/
Please let us know if you have any questions/comments!
December 5, 2024 at 2:52 PM
8/ You can find our code here:
github.com/alexgarciadu...
@alexgaduca.bsky.social also created great notebooks to help you fit our model to your data (choices, reaction time and motor time)!
December 5, 2024 at 2:52 PM
7/ Our model explains rat and human behavior well, but it raises questions: Could there be more than one update per trajectory—or even continuous updating? 🤔
December 5, 2024 at 2:52 PM
6/ Our model proposes two readouts of the decision variable: the first launches the trajectory, while the second adjusts it—speeding it up, slowing it down, or reversing it. Decision-making unfolds in real-time!
December 5, 2024 at 2:52 PM
5/ We tested humans in a similar task and found strikingly similar behaviors! This inspired us to build a model linking decision evidence accumulation with response execution, helping us understand how decisions dynamically shape movements.
December 5, 2024 at 2:52 PM
4/ 🔄 Sometimes rats changed their mind while responding. These trajectory reversals were seen more often when the stimulus strongly contradicted the initial path set by prior expectations, showing how flexibly the brain adjusts on the fly.
December 5, 2024 at 2:52 PM
3/ The prior set the trajectory from the start, but the stimulus only impacted movement after it began. It could accelerate or slow motion, depending on whether it aligns or contradicts it. Stimulus influence kicked in as early as 100ms after stimulus onset! ⏱️
December 5, 2024 at 2:52 PM
2/ 🐀 We tracked rats’ movements as they chose between two options using auditory stimuli and prior expectations. Movement speed scaled with how much prior/stimulus aligned with their choice—a fascinating link between cognitive variables and motor vigor rarely explored!
December 5, 2024 at 2:52 PM
1/ We explored what rat and human movements during decision-making reveal about brain computations 🧠
December 5, 2024 at 2:52 PM