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moe9621.bsky.social
@moe9621.bsky.social
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PhD candidate at @UniKarlova / member of the great @PlacentaHD /Specializing in Nucleotide Metabolism /alien ambassador 👽
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mpiage.bsky.social
📢 Publication Alert: We're excited to share a new study from the Langer Lab published in @nature.com! It uncovers how an excess of RNA building blocks can destabilize mitochondrial DNA, which plays a role in age-related inflammation.

www.nature.com/articles/s41...
Ribonucleotide incorporation into mitochondrial DNA drives inflammation - Nature
Imbalanced nucleotide metabolism leads to age- and mtDNA-dependent inflammatory responses and senescence-associated secretory phenotype in senescence.
www.nature.com
September 24, 2025 at 3:40 PM
moe9621.bsky.social
Ever wondered how the placenta fuels life?
We uncovered dynamic shifts in nucleos(t)ide metabolism & adenosine signaling across gestation and preterm birth
Now in Scientific Reports
#PretermBirth #purine_pyrimidne_de_novo_and_salvage_pathways
www.nature.com/articles/s41...
Dynamic shifts in trophoblast nucleos(t)ide metabolism, transport, and adenosine signaling during gestation and preterm birth - Scientific Reports
Scientific Reports - Dynamic shifts in trophoblast nucleos(t)ide metabolism, transport, and adenosine signaling during gestation and preterm birth
www.nature.com
September 9, 2025 at 8:47 PM