@mleyton.bsky.social
Instead of presenting the CS without the reward (standard extinction), the opposite approach should be taken: present the reward without its predictive cues and in the presence of cues rarely encountered in everyday life in order to reduce the likelihood that they will trigger a relapse
2/3
2/3
January 24, 2026 at 3:59 PM
Reposted
There is always an alternative
This is the title of the Dalbir Bindra 2025 lecture I've been invited to give tomorrow at McGill Univ.
I thank Pr Marco Leyton for the kind invitation 🙏
I hope I live up to this honor and that Bindra, wherever he is now, will find some of himself in my presentation.
This is the title of the Dalbir Bindra 2025 lecture I've been invited to give tomorrow at McGill Univ.
I thank Pr Marco Leyton for the kind invitation 🙏
I hope I live up to this honor and that Bindra, wherever he is now, will find some of himself in my presentation.
October 2, 2025 at 6:50 PM
There is always an alternative
This is the title of the Dalbir Bindra 2025 lecture I've been invited to give tomorrow at McGill Univ.
I thank Pr Marco Leyton for the kind invitation 🙏
I hope I live up to this honor and that Bindra, wherever he is now, will find some of himself in my presentation.
This is the title of the Dalbir Bindra 2025 lecture I've been invited to give tomorrow at McGill Univ.
I thank Pr Marco Leyton for the kind invitation 🙏
I hope I live up to this honor and that Bindra, wherever he is now, will find some of himself in my presentation.
Reposted
You can't gaslight me into thinking it's not butter
October 2, 2025 at 7:04 AM
You can't gaslight me into thinking it's not butter
Reposted
This fantastic work describes a novel mechanism by which the brain bridges the time gap between ingestion and its long-delayed post-ingestion consequences
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A neural mechanism for learning from delayed postingestive feedback - Nature
Illness signals from the gut reactivate and strengthen flavour representations in the amygdala to support learning from delayed postingestive feedback.
www.nature.com
June 19, 2025 at 9:20 AM
This fantastic work describes a novel mechanism by which the brain bridges the time gap between ingestion and its long-delayed post-ingestion consequences
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
Decriminalization or more treatment?
Recent evidence suggests that the overdose crisis is better addressed by increased treatment access than poorly implemented decriminalization programs.
➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250084
Recent evidence suggests that the overdose crisis is better addressed by increased treatment access than poorly implemented decriminalization programs.
➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250084
June 20, 2025 at 12:09 PM
Decriminalization or more treatment?
Recent evidence suggests that the overdose crisis is better addressed by increased treatment access than poorly implemented decriminalization programs.
➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250084
Recent evidence suggests that the overdose crisis is better addressed by increased treatment access than poorly implemented decriminalization programs.
➡️http://www.jpn.ca/lookup/doi/10.1503/jpn.250084
Reposted
Acute cannabidiol administration reduces alcohol craving and cue-induced nucleus accumbens activation in individuals with alcohol use disorder
www.nature.com/articles/s41...
www.nature.com/articles/s41...
May 22, 2025 at 2:29 PM
Acute cannabidiol administration reduces alcohol craving and cue-induced nucleus accumbens activation in individuals with alcohol use disorder
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
Alcohol sensory processing and its relevance for ingestion
This is an important, though unfortunately neglected, review article by Susan Brasser et al. on the critical role of the immediately rewarding sensory experience of ethanol
www.sciencedirect.com/science/arti...
This is an important, though unfortunately neglected, review article by Susan Brasser et al. on the critical role of the immediately rewarding sensory experience of ethanol
www.sciencedirect.com/science/arti...
May 6, 2025 at 9:53 AM
Alcohol sensory processing and its relevance for ingestion
This is an important, though unfortunately neglected, review article by Susan Brasser et al. on the critical role of the immediately rewarding sensory experience of ethanol
www.sciencedirect.com/science/arti...
This is an important, though unfortunately neglected, review article by Susan Brasser et al. on the critical role of the immediately rewarding sensory experience of ethanol
www.sciencedirect.com/science/arti...
Reposted
The Influence of Maternal Diet on Future Infant Taste and Odor Preferences
A deep and thoughtful analysis
www.annualreviews.org/content/jour...
A deep and thoughtful analysis
www.annualreviews.org/content/jour...
May 6, 2025 at 9:37 AM
The Influence of Maternal Diet on Future Infant Taste and Odor Preferences
A deep and thoughtful analysis
www.annualreviews.org/content/jour...
A deep and thoughtful analysis
www.annualreviews.org/content/jour...
Reposted
Dopamine sustains hedonic eating against GLP-1R satiety
This article also provides a nice summary of the activity of midbrain dopamine neurons during the different stages of hedonic eating, from initial food sight to post-ingestive reinforcement
www.science.org/doi/10.1126/...
This article also provides a nice summary of the activity of midbrain dopamine neurons during the different stages of hedonic eating, from initial food sight to post-ingestive reinforcement
www.science.org/doi/10.1126/...
March 28, 2025 at 9:03 AM
Dopamine sustains hedonic eating against GLP-1R satiety
This article also provides a nice summary of the activity of midbrain dopamine neurons during the different stages of hedonic eating, from initial food sight to post-ingestive reinforcement
www.science.org/doi/10.1126/...
This article also provides a nice summary of the activity of midbrain dopamine neurons during the different stages of hedonic eating, from initial food sight to post-ingestive reinforcement
www.science.org/doi/10.1126/...
Reposted
I asked Mistral AI to express the core ideas of my latest book chapter using the argumentative brilliance of the philosopher Thomas Nagel. Here's the result 👇
books.google.fr/books?hl=en&...
books.google.fr/books?hl=en&...
March 4, 2025 at 4:14 PM
I asked Mistral AI to express the core ideas of my latest book chapter using the argumentative brilliance of the philosopher Thomas Nagel. Here's the result 👇
books.google.fr/books?hl=en&...
books.google.fr/books?hl=en&...
Reposted
Trudeau: "I want to speak first directly to the American people. We don't want this. We want to work with you as a friend and ally. We don't want to see you hurt either. But your government has chosen to do this to you. As of this morning, markets are down and inflation is set to rise dramatically."
March 4, 2025 at 4:15 PM
Trudeau: "I want to speak first directly to the American people. We don't want this. We want to work with you as a friend and ally. We don't want to see you hurt either. But your government has chosen to do this to you. As of this morning, markets are down and inflation is set to rise dramatically."
Reposted
OMG Sarah Cooper is brilliant
www.youtube.com/watch?v=9cJ1...
www.youtube.com/watch?v=9cJ1...
The History of Wealth Throughout History
YouTube video by Sarah Cooper
www.youtube.com
February 16, 2025 at 7:10 PM
OMG Sarah Cooper is brilliant
www.youtube.com/watch?v=9cJ1...
www.youtube.com/watch?v=9cJ1...
Reposted
Structure of internalizing and externalizing symptoms in early adolescence: A comparison of a bifactor and a two-factor model over time and across reporters
www.cambridge.org/core/journal...
www.cambridge.org/core/journal...
Structure of internalizing and externalizing symptoms in early adolescence: A comparison of a bifactor and a two-factor model over time and across reporters | Development and Psychopathology | Cambrid...
Structure of internalizing and externalizing symptoms in early adolescence: A comparison of a bifactor and a two-factor model over time and across reporters
www.cambridge.org
February 17, 2025 at 1:59 PM
Structure of internalizing and externalizing symptoms in early adolescence: A comparison of a bifactor and a two-factor model over time and across reporters
www.cambridge.org/core/journal...
www.cambridge.org/core/journal...
Reposted
Many of us in academic science will default to “business as usual” as our response. We will feel that our power should be used to maintain a semblance of normalcy. To live to fight another day.
February 18, 2025 at 4:24 PM
Many of us in academic science will default to “business as usual” as our response. We will feel that our power should be used to maintain a semblance of normalcy. To live to fight another day.
Reposted
February 9, 2025 at 2:09 AM
Reposted
"To condone policies that the profession knows will compromise health—or to remain silent and look away—is to be complicit in putting population health at risk"
To every university, every public hospital, every academic society: SILENCE IS NOT AN OPTION. #medsky
To every university, every public hospital, every academic society: SILENCE IS NOT AN OPTION. #medsky
How Should Health Care and Public Health Respond to the New US Administration?
This Viewpoint discusses scientific, medical, and public health actions, including withdrawing from the World Health Organization, taken so far during the first week of the Trump administration.
jamanetwork.com
February 2, 2025 at 2:20 AM
"To condone policies that the profession knows will compromise health—or to remain silent and look away—is to be complicit in putting population health at risk"
To every university, every public hospital, every academic society: SILENCE IS NOT AN OPTION. #medsky
To every university, every public hospital, every academic society: SILENCE IS NOT AN OPTION. #medsky
Reposted
Testing addiction theories at home
People with alcohol use disorder, but with no desire to stop drinking, report changes in subjective experience during drinking that refute the hedonic allostasis theory of addiction.
psychiatryonline.org/doi/10.1176/...
People with alcohol use disorder, but with no desire to stop drinking, report changes in subjective experience during drinking that refute the hedonic allostasis theory of addiction.
psychiatryonline.org/doi/10.1176/...
February 3, 2025 at 11:35 AM
Testing addiction theories at home
People with alcohol use disorder, but with no desire to stop drinking, report changes in subjective experience during drinking that refute the hedonic allostasis theory of addiction.
psychiatryonline.org/doi/10.1176/...
People with alcohol use disorder, but with no desire to stop drinking, report changes in subjective experience during drinking that refute the hedonic allostasis theory of addiction.
psychiatryonline.org/doi/10.1176/...
Reposted
What a speech!
Dark times ahead for Americans and Canadians because of Trump.
youtu.be/xiaACQpFUfE?...
Dark times ahead for Americans and Canadians because of Trump.
youtu.be/xiaACQpFUfE?...
Trudeau: Canada will retaliate with 25% tariffs on $155B of U.S. goods
YouTube video by CBC News
youtu.be
February 2, 2025 at 3:21 PM
What a speech!
Dark times ahead for Americans and Canadians because of Trump.
youtu.be/xiaACQpFUfE?...
Dark times ahead for Americans and Canadians because of Trump.
youtu.be/xiaACQpFUfE?...