Maggie Walters
mkwalters3.bsky.social
Maggie Walters
@mkwalters3.bsky.social
PhD student at Imperial College London working to estimate HIV burden among children.

UW MPH ‘22/ ND '19
🏳️‍🌈she/her

Our paper was accompanied by a great commentary from Marcel Yotebieng on the implications of these results on ending paediatric HIV. Check it out here! www.thelancet.com/journals/lan...
Ending paediatric AIDS: time to close implementation gaps
WHO's global health sector strategies on HIV, conceived to guide the health sector in implementing strategically focused responses to achieve the goals of ending AIDS by 2030, target a reduction in th...
www.thelancet.com
August 4, 2025 at 4:00 PM
These new estimates were incorporated by @unaids.org for the most recent estimation round and result in higher estimates of paediatric HIV. Estimates of infections during breastfeeding were higher, which has implications for infant HIV testing programmes.
August 4, 2025 at 4:00 PM
Women on INSTI-based regimens (including DTG) had lower odds of transmission and higher odds of viral suppression by delivery than women receiving NNRTI-based regimens.

Most of these studies took place in high-income regions and our study emphasizes the need for more data from diverse regions.
August 4, 2025 at 4:00 PM
Like previous studies we found that transmission:

Women not on ART > Women using short-course ARVs > Women on ART > Women who start ART before pregnancy

Each additional week a woman was on ART before delivery reduced the odds of 5.6%!
August 4, 2025 at 4:00 PM
We screened over 400 full-texts and found 24 studies published since the start of 2018 (when these estimates were last updated).

We combined these with 86 studies that had been previously identified to estimate the probability of HIV transmission using four meta-regression models.
August 4, 2025 at 4:00 PM
Our work built on previous systematic reviews to estimate the probability that a mother living with HIV transmits HIV to their child.

We aimed to quantify changes in this probability that were due to:
1.) Changing service delivery models
2.) Introduction of dolutegravir (DTG) as a first line ART
August 4, 2025 at 4:00 PM