Mingqing Cai
@mingqingcai.bsky.social
Scientist in Pharma/Biotech for 15 years; therapeutic antibodies and other fancy modalities; cytokines and inflammation; cancer, autoimmune, and Alzheimer's disease.
DeepSeek~
It beats chatGPT in Chinese-based scenario and STEMs. Now let’s try drug discovery test.
Consideration session catches three main issues when optimizing affinity of an antibody: trade-off, expression, immunogenicity. Wonderful.
It beats chatGPT in Chinese-based scenario and STEMs. Now let’s try drug discovery test.
Consideration session catches three main issues when optimizing affinity of an antibody: trade-off, expression, immunogenicity. Wonderful.
January 28, 2025 at 9:31 AM
DeepSeek~
It beats chatGPT in Chinese-based scenario and STEMs. Now let’s try drug discovery test.
Consideration session catches three main issues when optimizing affinity of an antibody: trade-off, expression, immunogenicity. Wonderful.
It beats chatGPT in Chinese-based scenario and STEMs. Now let’s try drug discovery test.
Consideration session catches three main issues when optimizing affinity of an antibody: trade-off, expression, immunogenicity. Wonderful.
One thing I agree without reservation is not to put too much hope for future. Any actionable items should be done NOW instead of TOMORROW. But before that you need to decide which items on the list matter.
January 11, 2025 at 2:27 AM
One thing I agree without reservation is not to put too much hope for future. Any actionable items should be done NOW instead of TOMORROW. But before that you need to decide which items on the list matter.
Modern society takes time as a commodity and monetize it. Yes or No: for many professions there is positive association between time and productivity, but once time becomes the target to optimize, it ceases to work properly (Goodhart's law). A good book to read, Four Thousand Weeks.
January 2, 2025 at 10:35 AM
Modern society takes time as a commodity and monetize it. Yes or No: for many professions there is positive association between time and productivity, but once time becomes the target to optimize, it ceases to work properly (Goodhart's law). A good book to read, Four Thousand Weeks.
Day 20, The Diamond Age by Neal Stephenson
December 29, 2024 at 12:22 PM
Day 20, The Diamond Age by Neal Stephenson
This month I didn’t turn on heating system. Instead I spent the money on three books.
December 29, 2024 at 3:29 AM
This month I didn’t turn on heating system. Instead I spent the money on three books.
Day 19, The Annotated Origin by Charles Darwin & James Costa
December 28, 2024 at 1:00 AM
Day 19, The Annotated Origin by Charles Darwin & James Costa
Day 18, Logicomix by Apostolos Doxiadis
December 27, 2024 at 3:11 AM
Day 18, Logicomix by Apostolos Doxiadis
Day 17, The Denial of Death by Ernest Becker
December 26, 2024 at 7:27 AM
Day 17, The Denial of Death by Ernest Becker
Day 16, Superintelligence by Nick Bostrom
December 25, 2024 at 1:45 AM
Day 16, Superintelligence by Nick Bostrom
Day 15, An Odyssey by Daniel Mendelsohn
December 24, 2024 at 2:32 AM
Day 15, An Odyssey by Daniel Mendelsohn
Day 14, The Book of Why by Judea Pearl
December 23, 2024 at 12:46 AM
Day 14, The Book of Why by Judea Pearl
The youngsters are meant to see far to embrace the life and future while all left for the oldsters are within hand's reach: a coffee, a rose, or a book. Myopia and presbyopia sadden me cause I was there and now I am here.
December 22, 2024 at 7:42 AM
The youngsters are meant to see far to embrace the life and future while all left for the oldsters are within hand's reach: a coffee, a rose, or a book. Myopia and presbyopia sadden me cause I was there and now I am here.
Day 13, The Rest is Noise by Alex Ross
December 22, 2024 at 2:18 AM
Day 13, The Rest is Noise by Alex Ross
Day 12, Exhalation by Ted Chiang
December 21, 2024 at 5:24 AM
Day 12, Exhalation by Ted Chiang
Am I the only one feeling PubMed image is so surreal? I never see this kind in academia, not even in industrial or commercial offices. Maybe I'm talking about the hair thickness.
December 20, 2024 at 1:08 AM
Am I the only one feeling PubMed image is so surreal? I never see this kind in academia, not even in industrial or commercial offices. Maybe I'm talking about the hair thickness.
Day 11, Projection: A Story of Human Emotion by Karl Deisseroth
December 19, 2024 at 11:16 PM
Day 11, Projection: A Story of Human Emotion by Karl Deisseroth
Day 10, The Art of Statistics by David Spiegelhalter
December 19, 2024 at 1:12 AM
Day 10, The Art of Statistics by David Spiegelhalter
Day 9, The Beginning of Infinity by David Deutsch
December 18, 2024 at 2:33 AM
Day 9, The Beginning of Infinity by David Deutsch
Day 8, When We Cease to Understand the World by Benjamin Labatut
December 17, 2024 at 1:13 AM
Day 8, When We Cease to Understand the World by Benjamin Labatut
Day 7, Klara and the Sun by Kazuo Ishiguro
December 16, 2024 at 2:06 AM
Day 7, Klara and the Sun by Kazuo Ishiguro
I’m a big fan of David Glass’s Experimental Design for Biologists. Make biological experiments simple, variable-limited, controlled…High quality designs lead to reproducible data (I actually incorporate some of the ideas into job interview.)
December 16, 2024 at 1:17 AM
I’m a big fan of David Glass’s Experimental Design for Biologists. Make biological experiments simple, variable-limited, controlled…High quality designs lead to reproducible data (I actually incorporate some of the ideas into job interview.)
Day 6, Stories of Your Life by Ted Chiang
December 15, 2024 at 2:12 AM
Day 6, Stories of Your Life by Ted Chiang
Day 5, Other Minds by Peter Godfrey-Smith
December 14, 2024 at 1:14 AM
Day 5, Other Minds by Peter Godfrey-Smith
Day 4, The Grasshopper: Games, Life and Utopia by Bernard Suits
December 12, 2024 at 5:00 AM
Day 4, The Grasshopper: Games, Life and Utopia by Bernard Suits
Day 3, On the Move by Oliver Sacks
December 11, 2024 at 2:53 AM
Day 3, On the Move by Oliver Sacks