...by confronting our expectations with the "reality" of simulations.

Looking forward to your comments and opinions - please share what you think!

In the conversation, we explore the history of adaptive biasing force, or ABF, and its applications to #membrane systems or #alchemical simulations. We also discuss how to create impactful and useful #software, and make sure humans learn from interacting with biomolecular systems...

...using #Japan as an example where active effort is needed to remain well-integrated in the network.

I love to hear your feedback, and any questions or requests you might have about future episodes - don't hesitate to write!

...the development of tools for large-scale simulations within Yuji's code #GENESIS, and the current efforts toward #multiscale simulation of biologically relevant condensates. We also discuss the connectivity of the global scientific community, ...

...From his vast experience, Kresten also shares some tips for writing better grant proposals.

Looking forward to your feedback, and remember you can support the podcast on buymeacoffee.com/phasespaceinvaders ☕

In our conversation, Kresten gives great concrete examples of experimental developments being translated into breakthroughs in computational biophysics, as well as summarizes his latest research on proteome-wide coarse-grained modeling of intrinsically disordered protein regions. ...

...and the evolving role of academia.

A reminder that your feedback is always welcome, and that you can now support the podcast at buymeacoffee.com/phasespaceinvaders 🙌

We talk about what the current AI models are missing about statistical mechanics, and what the pathway might be to merge the two back together. With Pratyush's unbounded thirst for understanding complex matters, though, he also shares his thoughts on education, cognition and learning, creativity...

You can now support the podcast via buymeacoffee.com/phasespaceinvaders, yet there's nothing I value more than your direct feedback! If you have questions that should be asked or discussed, write to me - I will either ask them to my future guests or try to answer myself in the season finale.

With Ivet, we take a network-centric look at protein structures, discussing the evolution of dynamic signatures, allosteric communication, and bridging scales through the lens of elastic networks. Be persistent but alert - here's the advice Ivet has for young scientists starting their careers.

Beautiful stuff! 😲

Although barely discussed outside neurology, cerebral small vessel disease is a major aging-related driver of stroke, dementia, and disability🧠

It is a major public health concern without an available treatment📈

Huge unmet clinical need❗️

I'd hope this eventually pushes America into understanding the importance of stable public funding for research institutions, but my bet is it will turn them into VC corporations instead