Milene Vandal
@milenevandal.bsky.social
Postdoctoral associate University of Calgary
Brain vasculature & Alzheimer’s disease | Baking & trail running
Brain vasculature & Alzheimer’s disease | Baking & trail running
Félicitations à toute l’équipe !
February 5, 2025 at 4:21 PM
Félicitations à toute l’équipe !
Merci Baptiste !
February 1, 2025 at 6:20 PM
Merci Baptiste !
We found that CD2AP also regulates the levels and signalling of ApoER2, a receptor for reelin, in endothelial cells, that reelin induces vessel dilation and that the glycoprotein improves resting blood flow in mice with loss of brain endothelial CD2AP.
February 1, 2025 at 1:03 AM
We found that CD2AP also regulates the levels and signalling of ApoER2, a receptor for reelin, in endothelial cells, that reelin induces vessel dilation and that the glycoprotein improves resting blood flow in mice with loss of brain endothelial CD2AP.
Antagonizing the endothelin-1 receptor ET-A improves vascular function in males but not in females.
February 1, 2025 at 12:26 AM
Antagonizing the endothelin-1 receptor ET-A improves vascular function in males but not in females.
Reduction of brain endothelial CD2AP is linked to impaired brain vascular function and a worse response to amyloid-beta in male mice.
February 1, 2025 at 12:23 AM
Reduction of brain endothelial CD2AP is linked to impaired brain vascular function and a worse response to amyloid-beta in male mice.
Similarly, mice with loss of endothelial CD2AP have worse memory function.
February 1, 2025 at 12:19 AM
Similarly, mice with loss of endothelial CD2AP have worse memory function.
We found that loss of vascular CD2AD is link to worse cognitive function in Alzheimer’s disease volunteers.
February 1, 2025 at 12:13 AM
We found that loss of vascular CD2AD is link to worse cognitive function in Alzheimer’s disease volunteers.
We first confirmed that CD2AP is expressed in brain endothelial cells in mice and human.
February 1, 2025 at 12:11 AM
We first confirmed that CD2AP is expressed in brain endothelial cells in mice and human.