Mikolaj Kocikowski, PhD
@mikolajkocikowski.bsky.social
Bioinformatics · Cancer Immunology · Antibody Engineering · Omics · Networks - shaken, not stirred. Open Science · Open Source · DIY - with a touch of MTB 🇸🇪 (🇵🇱)
Reposted by Mikolaj Kocikowski, PhD
3. I am looking for a Swedish-speaking full-time research assistant who will contribute to data collection for the project above. Application deadline is January 7th liu.se/jobba-pa-liu... 3/3
liu.se
December 10, 2025 at 2:16 PM
3. I am looking for a Swedish-speaking full-time research assistant who will contribute to data collection for the project above. Application deadline is January 7th liu.se/jobba-pa-liu... 3/3
🐶 New preprint: DoggifAI
🤖 We built a transformer model that translates antibodies from mouse/human to dog “protein language” - preserving structure while reducing immunogenicity.
📂 Open model, code + dataset of 430k canine antibody sequences (largest to date): www.biorxiv.org/content/10.1...
🤖 We built a transformer model that translates antibodies from mouse/human to dog “protein language” - preserving structure while reducing immunogenicity.
📂 Open model, code + dataset of 430k canine antibody sequences (largest to date): www.biorxiv.org/content/10.1...
DoggifAI: a transformer based approach for antibody caninisation
Antibody translation across species offers a compelling strategy to extend the vast and expensive investments in human therapeutic antibodies to veterinary oncology, with applications in both veterina...
www.biorxiv.org
May 30, 2025 at 3:29 PM
🐶 New preprint: DoggifAI
🤖 We built a transformer model that translates antibodies from mouse/human to dog “protein language” - preserving structure while reducing immunogenicity.
📂 Open model, code + dataset of 430k canine antibody sequences (largest to date): www.biorxiv.org/content/10.1...
🤖 We built a transformer model that translates antibodies from mouse/human to dog “protein language” - preserving structure while reducing immunogenicity.
📂 Open model, code + dataset of 430k canine antibody sequences (largest to date): www.biorxiv.org/content/10.1...
New preprint out! We expand the concept of MHC-I promiscuity - from peptides to populations - to support cancer vaccine discovery. The CARMEN database harmonizes data from 72 studies and 2,300+ cancer samples.
doi.org/10.1101/2025...
#bioinformatics #immunotherapy #cancerresearch #preprint
doi.org/10.1101/2025...
#bioinformatics #immunotherapy #cancerresearch #preprint
Expanding the definition of MHC Class I peptide binding promiscuity to support vaccine discovery across cancers with CARMEN
Promiscuity in T-cell antigen landscapes refers to the dual flexibility of peptides binding multiple MHC alleles and MHC alleles presenting diverse arrays of peptides. By understanding how neoantigens...
doi.org
May 11, 2025 at 11:21 AM
New preprint out! We expand the concept of MHC-I promiscuity - from peptides to populations - to support cancer vaccine discovery. The CARMEN database harmonizes data from 72 studies and 2,300+ cancer samples.
doi.org/10.1101/2025...
#bioinformatics #immunotherapy #cancerresearch #preprint
doi.org/10.1101/2025...
#bioinformatics #immunotherapy #cancerresearch #preprint
Win10 support ending soon means lots of “old” computers might be trashed - not because they’re broken, but because they can’t run Win11. endof10.org encourages people to switch to Linux. When I did, I expected some pain - got joy and relief instead! If you need a hand to switch, I’m happy to help.
End of 10
Support for Windows 10 ends on October 14, 2025.
endof10.org
May 3, 2025 at 8:34 PM
Win10 support ending soon means lots of “old” computers might be trashed - not because they’re broken, but because they can’t run Win11. endof10.org encourages people to switch to Linux. When I did, I expected some pain - got joy and relief instead! If you need a hand to switch, I’m happy to help.