Zach LaTurner
micronaut.bsky.social
Zach LaTurner
@micronaut.bsky.social
Postdoc in Cress Lab @ Innovative Genomics Institute. I am interested in horizontal gene transfer and microbial community engineering to help the environment.
Finally, we dug into one of the elements that determines P1 host range by characterizing hosts associated with P1s two unique tail fibers. RAM detected statistically significant enrichment of hosts infected by phages containing one tail fiber relative to the other tail fiber. 5/6
May 6, 2025 at 10:37 PM
The ease with which RAM can be used in real microbial communities is one of its biggest advantages as a host identification tool. When we added our modified P1 to wastewater influent, RAM identified known hosts in the Enterobacterales family and completely novel hosts in the Aeromonadales order. 4/6
May 6, 2025 at 10:37 PM
When added to the genome of P1 and P1 phagemids, RAM was able to barcode known P1 hosts in monoculture. We also added the constructs to a synthetic community of ESKAPE pathogens to assay host potential of many organisms at once and identified a novel host of P1 phagemids in Salmonella enterica. 3/6
May 6, 2025 at 10:37 PM