Michael Hunter
@michaelhunter26.bsky.social
Postdoc at UBC studying phage evolution. Modelling and experiments.
Reposted by Michael Hunter
Excited to share our latest preprint led by Dr. Hunter! We show that osmotic shifts, common in the gut, alter T4 phage-E. coli evolution. High osmolality promotes fitness but selects for mucoid, weakly phage-resistant E. coli, with implications for phage therapy! biorxiv.org/content/10.1...
Osmotic conditions shape fitness gains and resistance mechanisms during E. coli and T4 phage co-evolution
Bacteriophages, or phages, are viruses that infect bacteria and offer a promising approach to combating antimicrobial resistance in the gut by selectively targeting harmful bacteria while preserving t...
biorxiv.org
March 19, 2025 at 1:19 AM
Excited to share our latest preprint led by Dr. Hunter! We show that osmotic shifts, common in the gut, alter T4 phage-E. coli evolution. High osmolality promotes fitness but selects for mucoid, weakly phage-resistant E. coli, with implications for phage therapy! biorxiv.org/content/10.1...