Michael Aregger
@michaelaregger.bsky.social
Studying genetic interactions in cancer cells using CRISPR-based functional genomics approaches at NCI/NIH. Views are my own.
Reposted by Michael Aregger
www.nature.com/articles/s41... A collaborative project incepted by Michael Kosicki, and executed by Ananth Pallaseni (both Ph.D students at @sangerinstitute.bsky.social at the time) and Elin-Madli Peets.
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations - Nature Communications
Here the authors measure how the absence of certain DNA repair genes change the frequencies of unique mutational outcomes generated by Cas9 DSBs at synthetic target sequences in mouse embryonic stem c...
www.nature.com
November 28, 2024 at 6:37 AM
www.nature.com/articles/s41... A collaborative project incepted by Michael Kosicki, and executed by Ananth Pallaseni (both Ph.D students at @sangerinstitute.bsky.social at the time) and Elin-Madli Peets.