an incredibly dedicated team of clinical trialists, basic and translational researchers and immune monitoring team @dkfz.bsky.social, @dkfz-iic.bsky.social, I have the privilege to work with with the goal to develop a viable tratment for patients with this devastating disease. 5/5

@neurooncologyhd.bsky.social @neurooncotue.bsky.social, Frankfurt, Mannheim, all patients and their relatives, Roche for the in-kind contribution of atezolizumab, the fantastic research collaborators @bihatcharite.bsky.social and HI-TRON, and first and foremost 4/

in this "reverse translation" trial which was supported by the German Cancer Aid. Huge thanks to @dkfz.bsky.social as the trial sponsor, the fantastic NCT Trial Center, all participating sites from the Neurooncology Working Group @krebsgesellschaft.bsky.social 3/

combined with radiotherapy and the immune checkpoint inhibitor atezolizumab. The trial was based on encouraging results in patients with recurrent diffuse midline gliomas

www.nature.com/articles/s41...

We will now follow-up our patiens, analyze the data and continue our analyses 2/

Fantastic initiative - we could offer to provide our predicTCR and makeTCR tools to identify tumor-reactive TCRs and clone them for testing.

www.nature.com/articles/s41...

www.biorxiv.org/content/10.1...

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