Mindaugas Galvosas, MD
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mgalvosas.bsky.social
Mindaugas Galvosas, MD
@mgalvosas.bsky.social
Cough as a Digital Biomarker and First Digital Therapeutic (DTx) for chronic cough @ hyfe.com, coughpro.com | prev. founder of wandering prevention tech for dementia | interested in Digital Health | my opinions
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Hey BSKY, I'm building the Digital Health Starter Pack to stay up to date with the innovation and POVs.

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Today, the U.S. Food and Drug Administration approved Boehringer Ingelheim’s nerandomilast (Jascayd) for the treatment of progressive pulmonary fibrosis (PPF) in adults.

This decision follows the FDA’s Oct. 7, 2025, approval of Jascayd for idiopathic pulmonary fibrosis (IPF).
December 19, 2025 at 9:49 PM
Telehealth Works for Weight Loss!

The first study to evaluate both the long-term weight loss and safety outcomes of GLP-1 treatment via telehealth.

onlinelibrary.wiley.com/doi/ftr/10.1...
onlinelibrary.wiley.com
December 17, 2025 at 9:22 PM
Digital health industry is moving faster than ever, and AI is only going to keep accelerating innovation.
December 17, 2025 at 9:20 PM
Is science diplomacy still possible?

In a world of strategic rivalry, fragmented multilateralism, and techno-nationalism, can science diplomacy still serve as a bridge for cooperation?

By Ilona Kickbusch

www.thelancet.com/journals/lan...
Is science diplomacy still possible?
In a world of strategic rivalry, fragmented multilateralism, and techno-nationalism, can science diplomacy still serve as a bridge for cooperation? There is an emerging consensus that global health mu...
www.thelancet.com
December 16, 2025 at 3:06 PM
AI finds a surprising monkeypox weak spot that could rewrite vaccines

www.science.org/doi/10.1126/...
Antigen-agnostic identification of poxvirus broadly neutralizing antibodies targeting OPG153
Antigen-agnostic isolation of B cells enabled the AI-assisted identification of broadly neutralizing antibodies targeting OPG153.
www.science.org
December 16, 2025 at 3:03 PM
So many people are coughing in the airport today; only a tiny % of them are monitoring their cough dynamics objectively using some cough tracking app.

Soon cough insights will be ubiquitous and as mainstream as step counting is today, equipping most of us with powerful insights.
December 16, 2025 at 9:13 AM
Wearable cough monitors (eg smartwatch) enable ambulatory assessment that captures real-world disease burden. This contrasts with clinic-based evaluations that may not reflect typical patient experiences.
December 16, 2025 at 9:10 AM
Moderate correlation between CQA6 and the Cough Hypersensitivity Questionnaire indicates that asthma patients exhibit features of cough hypersensitivity.

This overlaps with mechanisms described in chronic refractory cough, suggesting shared pathophysiology.
December 16, 2025 at 9:10 AM
I’ve been playing Mansions of Madness (2nd edition) this weekend and turns out Claude’s Opus 4.5 is incredibly bad at understanding the rules for this game!

Has anyone else experienced something similar with board game rules?
December 16, 2025 at 9:09 AM
Hiring a fully remote (ideally Europe-based) Partnerships Associate at hyfe.com

You would:
-Work with pharmaceutical, biopharma, and medical device partners
-Learn about the field of cough monitoring and its insights
-Be part of a fast-growing company

DM!

Please share
Hyfe - Detect & Quantify Cough
Hyfe provides consistently reliable, high-quality cough data, collected unobtrusively, delivering precise insights and dependable results
hyfe.com
December 15, 2025 at 7:22 AM
What will ambulance + emergency care and healthcare look like in space?

Given the promising developments from Musk, Bezos et al on data centers in orbit & extraterrestrial settlements - someone should really take a stab at healthcare. Has any progress been made yet?
December 12, 2025 at 9:10 AM
Top 10 Most Used AI Tools By Physicians

Interesting to see OpenEvidence as #1 and by far!

What are your favourite AI tools for daily practice?
December 12, 2025 at 8:55 AM
Japan turns to AI, robot caregivers to tackle dementia

The Health Ministry projects that dementia-related health and social care costs will reach 14 trillion yen by 2030, up from nine trillion yen in 2025.

www.firstpost.com/health/japan...
www.firstpost.com
December 11, 2025 at 3:16 PM
More than 20 years ago, Slovenia adopted a chronic disease prevention strategy that is now showing impressive results - and becoming a model for other countries.
December 11, 2025 at 3:15 PM
NEW! A blood-based biomarker of intestinal damage and inflammation could help to identify children at greatest risk of dying post-hospitalization in low-resource parts of the world.

www.nature.com/articles/s41...
Plasma lipopolysaccharide levels predict mortality in acutely ill children in Low- and Middle-Income Countries - Nature Communications
Childhood mortality is a global health problem. Plasma lipopolysaccharide levels, inflammatory stool biomarkers and proteomics were used in a nested case-cohort in sub-Saharan Africa and South Asia to...
www.nature.com
December 11, 2025 at 3:12 PM
The value of continuous cough monitoring: a narrative review - highlighting the modern cough monitoring tools

jtd.amegroups.org/article/view...
The value of continuous cough monitoring: a narrative review
The value of continuous cough monitoring: a narrative review
jtd.amegroups.org
December 11, 2025 at 1:25 PM
Top-selling drugs globally - the forecast for 2026

Many GLP agonists - we might see more associated cough.

Due to heightened cough hypersensitivity? Might be addressed with digital interventions.

Cough pattern? Can be described and monitored with continuous cough monitoring.
December 11, 2025 at 8:50 AM
Potential to combine wearable data with digital treatment is huge; that’s exactly what we’re doing at Hyfe - combining the two:

1. Behavioural treatment for cough hypersensitivity

2. Objective cough monitoring providing a biofeedback loop

endpoints.news/tech-emerges...
Tech emerges as a new frontier for digital therapeutics
Tech companies are approaching Click Therapeutics about partnerships, as CEO David Benshoof Klein sees potential to combine wearable data with FDA-authorized digital treatments.
endpoints.news
December 10, 2025 at 4:46 PM
CMS will reimburse healthcare organizations for patients’ wearable and app use if it improves their health conditions

www.beckershospitalreview.com/healthcare-i...
www.beckershospitalreview.com
December 10, 2025 at 4:03 PM
The FDA launched a first-of-its-kind Technology-Enabled Meaningful Patient Outcomes pilot to expand access to digital health devices for chronic condition management.

www.fda.gov/news-events/...
FDA Launches TEMPO: A First-of-Its-Kind Digital Health Pilot to Expand Access to Chronic Disease Technologies
FDA Launches TEMPO: A First-of-Its-Kind Digital Health Pilot to Expand Access to Chronic Disease Technologies
www.fda.gov
December 10, 2025 at 4:01 PM
The first randomized controlled trials for ambient AI scribes in healthcare have finally arrived - suggesting that scribes deliver… some time savings

Digging into it:
December 10, 2025 at 3:56 PM
Children exposed to extreme heat are less likely to meet basic developmental milestones than children living nearby in cooler areas, finds a study of 20,000 children; low-income children are especially vulnerable.

acamh.onlinelibrary.wiley.com/doi/10.1111/...
<em>Journal of Child Psychology and Psychiatry</em> | ACAMH Pediatric Journal | Wiley Online Library
Background Increasing evidence suggests that climate change, along with its cascading impacts on ecosystems, societies, and communities, has significant effects on both physical and mental health. H...
acamh.onlinelibrary.wiley.com
December 10, 2025 at 3:41 PM
I was once called a ‘cough boy’ at an event

I look forward to being a real ‘cough man’ - soon, when cough monitoring and cough insights are as mainstream as step counting today
December 10, 2025 at 3:33 PM
For a decade after its discovery, CRISPR gene editing was stuck on the cusp of transforming medicine.

This year, gene-editing technology was customized to fix mutations in a single patient’s genes for the first time.

www.theatlantic.com/science/2025...
The Rarest of All Diseases Are Becoming Treatable
This year, gene-editing technology was customized to fix mutations in a single patient’s genes for the first time.
www.theatlantic.com
December 9, 2025 at 3:40 PM