Migle Gabrielaite
@mgabrielaite.bsky.social
Marie Sklodowska Curie Actions Postdoc at Vilnius University 🇱🇹 | Previously Rigshospitalet & University of Copenhagen 🇩🇰 | Bioinformatician 🧑💻 | Exploring bacterial evolution & transmission 🦠 | Toddler mom 🧒
Even though talks at a conference are always cool, the most exciting part of #EYSF2025 is the @nightsciencepod.bsky.social workshop by @itaiyanai.bsky.social and @martinlercher.bsky.social . They are a great resource for scientific creativity and they even have a podcast!
September 25, 2025 at 11:39 AM
Even though talks at a conference are always cool, the most exciting part of #EYSF2025 is the @nightsciencepod.bsky.social workshop by @itaiyanai.bsky.social and @martinlercher.bsky.social . They are a great resource for scientific creativity and they even have a podcast!
Next, at #EYSF2025 @reviewcommons.org is presented by @saramonaco-rc.bsky.social. It’s journal-agnostic, concentrates on science only and can save time as the peer-reviewed preprints can easily be resubmitted. How great would it be if we could ditch publishing and switch to reviewed preprints?
September 24, 2025 at 12:27 PM
Next, at #EYSF2025 @reviewcommons.org is presented by @saramonaco-rc.bsky.social. It’s journal-agnostic, concentrates on science only and can save time as the peer-reviewed preprints can easily be resubmitted. How great would it be if we could ditch publishing and switch to reviewed preprints?
Continuing #EYSF2025 on CRISPR-Cas, Stephan Rieserberg is presenting how they developed cool tools to efficiently break complicated dsDNA targets and where conventional methods barely work. Also, there are cool CRISPR-Cas based methods to get rid of everything where initial DNA editing didn’t work.
September 24, 2025 at 12:21 PM
Continuing #EYSF2025 on CRISPR-Cas, Stephan Rieserberg is presenting how they developed cool tools to efficiently break complicated dsDNA targets and where conventional methods barely work. Also, there are cool CRISPR-Cas based methods to get rid of everything where initial DNA editing didn’t work.
Even though Cas9 technology is promising in many fields, including gene therapy, it still has many limitations to overcome before its’ full potential can be used. For example, different Cas nucleases require different PAM sequences for cleavage to happen which Šikšnys lab is now working on solving.
September 24, 2025 at 7:06 AM
Even though Cas9 technology is promising in many fields, including gene therapy, it still has many limitations to overcome before its’ full potential can be used. For example, different Cas nucleases require different PAM sequences for cleavage to happen which Šikšnys lab is now working on solving.
As the conference season continues, it’s time for EMBO Young Scientists’ Forum in Vilnius. The day starts with a talk by Prof. Virginijus Šikšnys about bacteria antiviral defense systems, and how his lab was among the first to show that Cas9 can be used for programmable DNA cleavage.
#EYSF2025
#EYSF2025
September 24, 2025 at 7:06 AM
As the conference season continues, it’s time for EMBO Young Scientists’ Forum in Vilnius. The day starts with a talk by Prof. Virginijus Šikšnys about bacteria antiviral defense systems, and how his lab was among the first to show that Cas9 can be used for programmable DNA cleavage.
#EYSF2025
#EYSF2025
Now that #IMMEMXIV has ended, I can say that it was one of the best conferences I have ever attended. Fantastic and diverse (!) speakers, incredibly good posters, good food and enough wine to make the experience truly unforgettable. Happy to have met so many inspiring scientists!
September 20, 2025 at 4:27 PM
Now that #IMMEMXIV has ended, I can say that it was one of the best conferences I have ever attended. Fantastic and diverse (!) speakers, incredibly good posters, good food and enough wine to make the experience truly unforgettable. Happy to have met so many inspiring scientists!
Third day of #IMMEMXIV starts with a session on environmental surveillance and its importance for infectious diseases and AMR control. Before starting the day, together with the shark I got to explore truly stunning Porto.
September 19, 2025 at 8:23 AM
Third day of #IMMEMXIV starts with a session on environmental surveillance and its importance for infectious diseases and AMR control. Before starting the day, together with the shark I got to explore truly stunning Porto.
The last presentation is by Val Fernandez Lanza about BacTaxID - genome-based, scalable, hierarchical, heuristic bacterial typing method. Similar to LIN and EC codes. The shark is very excited for the upcoming poster session.
September 18, 2025 at 4:16 PM
The last presentation is by Val Fernandez Lanza about BacTaxID - genome-based, scalable, hierarchical, heuristic bacterial typing method. Similar to LIN and EC codes. The shark is very excited for the upcoming poster session.
Next, Verónica Mixão is presenting ReporTree for linking pathogen genetic clusters with epidemiological dat and how it can implement wgMLST data for extra resolution.
September 18, 2025 at 4:16 PM
Next, Verónica Mixão is presenting ReporTree for linking pathogen genetic clusters with epidemiological dat and how it can implement wgMLST data for extra resolution.
Matthijs S. Berends continues #IMMEMXIV bioinformatics session with the presentation of AMRgen that combines genotype and phenotype data and interpretation. It definitely should save hours of manual labor (at least for bacteria with known resistance mechanisms).
September 18, 2025 at 4:16 PM
Matthijs S. Berends continues #IMMEMXIV bioinformatics session with the presentation of AMRgen that combines genotype and phenotype data and interpretation. It definitely should save hours of manual labor (at least for bacteria with known resistance mechanisms).
It covered QC guidelines, assembly graph interpretation, metagenomics, microbial typing specifications, AllTheBacteria workflow implementation on nextflow and interactive and easy-to-use AMR exploration of AllTheBacteria, and plasmid outbreak reporting.
September 18, 2025 at 3:09 PM
It covered QC guidelines, assembly graph interpretation, metagenomics, microbial typing specifications, AllTheBacteria workflow implementation on nextflow and interactive and easy-to-use AMR exploration of AllTheBacteria, and plasmid outbreak reporting.
The most anticipated session at #IMMEMXIV is, of course, about bioinformatics. It starts with presentation of the hackathon that took place prior to the conference. All the code is on GitHub (link in the pictures).
September 18, 2025 at 3:09 PM
The most anticipated session at #IMMEMXIV is, of course, about bioinformatics. It starts with presentation of the hackathon that took place prior to the conference. All the code is on GitHub (link in the pictures).
Continuing #IMMEMXIV with Benjamin Howden and genomic surveillance and how it can help control and prevent outbreaks and make informed decisions. However, for it to work we need to ensure that not only the infrastructure is there but also that the insights can be used for decision making.
September 18, 2025 at 10:16 AM
Continuing #IMMEMXIV with Benjamin Howden and genomic surveillance and how it can help control and prevent outbreaks and make informed decisions. However, for it to work we need to ensure that not only the infrastructure is there but also that the insights can be used for decision making.
Taxonomy matters and if we call the same strain different names in different countries, we quickly run into problems not knowing what’s happening around us. @sylvainbrisse.bsky.social is defining the main requirements and offers a solution using cgMLST and LIN codes.
September 18, 2025 at 8:21 AM
Taxonomy matters and if we call the same strain different names in different countries, we quickly run into problems not knowing what’s happening around us. @sylvainbrisse.bsky.social is defining the main requirements and offers a solution using cgMLST and LIN codes.
Also, I am attending the conference with the little shark given by my son so I wouldn’t be bored. Today we managed to get to the ocean before the start of the day and enjoy the beauty of Porto.
September 18, 2025 at 8:03 AM
Also, I am attending the conference with the little shark given by my son so I wouldn’t be bored. Today we managed to get to the ocean before the start of the day and enjoy the beauty of Porto.
GTDB sometimes assigns suffixes for non monophyletic taxa where historically the classification is misleading or ambiguous. And we should all do better when submitting our genomes to public databases and naming species.
September 18, 2025 at 8:03 AM
GTDB sometimes assigns suffixes for non monophyletic taxa where historically the classification is misleading or ambiguous. And we should all do better when submitting our genomes to public databases and naming species.
The second day of #immemxiv in Porto starts with GTDB taxonomy by Maria Chuvochina. NCBI often lacks species assignments and, from my personal experience, can be incorrect often than expected. Also, ~2% of all species are fuzzy/hard to discriminate by ANI.
September 18, 2025 at 8:03 AM
The second day of #immemxiv in Porto starts with GTDB taxonomy by Maria Chuvochina. NCBI often lacks species assignments and, from my personal experience, can be incorrect often than expected. Also, ~2% of all species are fuzzy/hard to discriminate by ANI.
1. When did AI become so good with figures and text?!
2. I am really looking for a PhD student (deadline in June)
2. I am really looking for a PhD student (deadline in June)
April 15, 2025 at 7:33 AM
1. When did AI become so good with figures and text?!
2. I am really looking for a PhD student (deadline in June)
2. I am really looking for a PhD student (deadline in June)
I spent a week in Georgia 🇬🇪 talking about genomic epidemiology: from the very basics to case studies and false information as a part of the EU funded TWINNING project. It was a week full of beautiful Tbilisi 🏔, incredible food 🥘 and insightful discussions about the power of genomic epidemiology 🧬.
April 14, 2025 at 8:57 AM
I spent a week in Georgia 🇬🇪 talking about genomic epidemiology: from the very basics to case studies and false information as a part of the EU funded TWINNING project. It was a week full of beautiful Tbilisi 🏔, incredible food 🥘 and insightful discussions about the power of genomic epidemiology 🧬.
Apart from many of these prizes being awarded to quite funny discoveries, they do indeed have another layer to think about and they highlight the most important thing about science: curiosity about the world around us. It's great to be reminded that science doesn't always have to be serious.
March 19, 2025 at 3:06 PM
Apart from many of these prizes being awarded to quite funny discoveries, they do indeed have another layer to think about and they highlight the most important thing about science: curiosity about the world around us. It's great to be reminded that science doesn't always have to be serious.
Day 3 of #TheCOINS with an amazing keynote Kees Moeliker, an Ig Nobel Prize winner. Ig Nobel is awarded to discoveries that make people laugh and then think. Picture shows the detailed notes of an observation of homosexual duck necrophilia case.
March 19, 2025 at 3:06 PM
Day 3 of #TheCOINS with an amazing keynote Kees Moeliker, an Ig Nobel Prize winner. Ig Nobel is awarded to discoveries that make people laugh and then think. Picture shows the detailed notes of an observation of homosexual duck necrophilia case.
The COINS conference is kicking off with very strong and inspiring talks by @marienordstrom.bsky.social about ecology and food webs and @kellykrause.bsky.social about scientific visualizations
March 17, 2025 at 1:52 PM
The COINS conference is kicking off with very strong and inspiring talks by @marienordstrom.bsky.social about ecology and food webs and @kellykrause.bsky.social about scientific visualizations
AI and LLMs are great for a lot of things and can make our life easier and more efficient. AI nanny and guide for sleep-deprived, tired and desperate parents, however, is dangerous.
November 15, 2024 at 8:56 PM
AI and LLMs are great for a lot of things and can make our life easier and more efficient. AI nanny and guide for sleep-deprived, tired and desperate parents, however, is dangerous.