(usually given at age 4-5, ie before school) is not a “booster” (does not need to be timed close to school) but to catch the 5-7% who didn’t respond to the first dose. The second dose can be given sooner as long as it’s 28 days apart. Our pediatrician was very happy to do so for our 3 year old.

Children get their first dose of MMR at 12-15 months in the routine vaccine schedule - I think most people including parents don’t realize that ALL infants are unprotected until that first dose. The second dose at age 4 is to catch non-responders to the first dose (not a booster), so can give early!

❗️Veterans with both very high cardiometabolic risk and heavy alcohol burden had clinical outcomes closer to MetALD than ALD.
❓Should we be classifying everyone with a certain threshold of alcohol use as ALD regardless of other clinical traits?
(4/4)

Classification of SLD varied *dramatically* depending on our choices as investigators.

❗️Beware misclassifying SLD based on absent/missing information about alcohol.
❗️⬆️ triglycerides and ⬇️ HDL are metabolic effects of alcohol use, and can be misleading in classifying SLD
(3/4)

Medical records are notoriously bad (biased, non-standardized) at capturing routine alcohol consumption. At the VA, alcohol use is measured annually for all primary care patients.
We compared 7 different SLD classification systems with varying alcohol and metabolic risk thresholds.
(2/4)