Martin Esparza-Iaizzo
@mesparza-iaizzo.bsky.social
PhD Student at the Be.Neuro Lab in Imperial College London and Neuroengineer at INBRAIN Neuroelectronics
Reposted by Martin Esparza-Iaizzo
Preprint out -- using intramuscular microelectrode arrays to detect residual motoneuron activity in tetraplegic spinal cord injury, and then using that activity for control
Credit to my other co-first authors Agnese Grison and Ciara Gibbs
1/n
www.medrxiv.org/content/10.1...
Credit to my other co-first authors Agnese Grison and Ciara Gibbs
1/n
www.medrxiv.org/content/10.1...
Multidimensional motoneuron control using intramuscular microelectrode arrays in tetraplegic spinal cord injury
Loss of hand function after spinal cord injury (SCI) significantly impairs independence and quality of life. Although residual muscle activity recorded on the skin can provide intuitive control signal...
www.medrxiv.org
July 18, 2025 at 6:56 PM
Preprint out -- using intramuscular microelectrode arrays to detect residual motoneuron activity in tetraplegic spinal cord injury, and then using that activity for control
Credit to my other co-first authors Agnese Grison and Ciara Gibbs
1/n
www.medrxiv.org/content/10.1...
Credit to my other co-first authors Agnese Grison and Ciara Gibbs
1/n
www.medrxiv.org/content/10.1...
Reposted by Martin Esparza-Iaizzo
🚨 Upcoming postdoc openings 🚨
We will soon be hiring postdocs to work on neural data analysis & modelling in the context of a recently awarded ARIA grant aimed at "precision control" of neural population dynamics (w. collabs. across the UK)
Reach out if interested!
www.aria.org.uk/opportunity-...
We will soon be hiring postdocs to work on neural data analysis & modelling in the context of a recently awarded ARIA grant aimed at "precision control" of neural population dynamics (w. collabs. across the UK)
Reach out if interested!
www.aria.org.uk/opportunity-...
Precision Neurotechnologies
Backed by £69m, this programme aims to unlock new methods to interface with the human brain at the cellular level, with unprecedented precision.
www.aria.org.uk
August 4, 2025 at 10:32 AM
🚨 Upcoming postdoc openings 🚨
We will soon be hiring postdocs to work on neural data analysis & modelling in the context of a recently awarded ARIA grant aimed at "precision control" of neural population dynamics (w. collabs. across the UK)
Reach out if interested!
www.aria.org.uk/opportunity-...
We will soon be hiring postdocs to work on neural data analysis & modelling in the context of a recently awarded ARIA grant aimed at "precision control" of neural population dynamics (w. collabs. across the UK)
Reach out if interested!
www.aria.org.uk/opportunity-...
Reposted by Martin Esparza-Iaizzo
Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world!
🔗: www.nature.com/articles/s41...
📄: rdcu.be/ex8hW
🔗: www.nature.com/articles/s41...
📄: rdcu.be/ex8hW
A neural manifold view of the brain - Nature Neuroscience
Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds. Understanding how nature, nurture...
www.nature.com
July 29, 2025 at 7:06 PM
Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world!
🔗: www.nature.com/articles/s41...
📄: rdcu.be/ex8hW
🔗: www.nature.com/articles/s41...
📄: rdcu.be/ex8hW
Reposted by Martin Esparza-Iaizzo
🚨New paper🚨
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
August 1, 2025 at 9:57 AM
🚨New paper🚨
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
Reposted by Martin Esparza-Iaizzo
New from the lab!! 👉🏼 authors.elsevier.com/a/1kgT43BtfH... 📝 @cellpress.bsky.social We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With Juan Gallego @juangallego.bsky.social
February 26, 2025 at 4:16 PM
New from the lab!! 👉🏼 authors.elsevier.com/a/1kgT43BtfH... 📝 @cellpress.bsky.social We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With Juan Gallego @juangallego.bsky.social
Reposted by Martin Esparza-Iaizzo
If you want to distract yourself from all the doomscrolling read through Jason's thread on this important piece of science
Congratulations guys!
Congratulations guys!
(1/11) Today I preprinted a lot of work from my postdoc with @dudman.bsky.social, which started with a question of how the nervous system balances flexibility with efficiency of learning. The thread below gives some background....
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Cortical control of innate behavior from subcortical demonstration
Motor control in mammals is traditionally viewed as a hierarchy of descending spinal-targeting pathways, with frontal cortex at the top. Many redundant muscle patterns can solve a given task, and this...
www.biorxiv.org
February 17, 2025 at 7:43 PM
If you want to distract yourself from all the doomscrolling read through Jason's thread on this important piece of science
Congratulations guys!
Congratulations guys!
Reposted by Martin Esparza-Iaizzo
We have a great program lined up for NCM 2025 in Panama! Poster submissions are open until Feb 17th. #NCMPan25
The #NCMPan25 program is now available! Review the talks, panels, and more and make your plans for Panama.
January 30, 2025 at 7:41 PM
We have a great program lined up for NCM 2025 in Panama! Poster submissions are open until Feb 17th. #NCMPan25
Reposted by Martin Esparza-Iaizzo
Our paper from Junchol Park and collaborators that has been brewing for a while. Trying to capture our thinking about what action specification in striatum means and what would constitute evidence for such a model. Longer thread soon, but it’s online now. www.cell.com/neuron/fullt...
Conjoint specification of action by neocortex and striatum
Park et al. show that motor cortex and subcortical striatum act in concert to specify
the movement parameters of a reach-to-pull action in mice.
www.cell.com
January 24, 2025 at 1:34 AM
Our paper from Junchol Park and collaborators that has been brewing for a while. Trying to capture our thinking about what action specification in striatum means and what would constitute evidence for such a model. Longer thread soon, but it’s online now. www.cell.com/neuron/fullt...
Reposted by Martin Esparza-Iaizzo
2/2 Alex Hyafil (neurons & cognition)
Mireia Torralba (EEG, fMRI)
Klaus Wimmer (neurons & cognition)
Damian Blasi (language)
Juanma Toro (language)
upf.edu/web/mbc/acce...
You will learn all you need to do research in cognitive and computational neuroscience
Mireia Torralba (EEG, fMRI)
Klaus Wimmer (neurons & cognition)
Damian Blasi (language)
Juanma Toro (language)
upf.edu/web/mbc/acce...
You will learn all you need to do research in cognitive and computational neuroscience
Master in Brain and Cognition - Access & admission
upf.edu
December 1, 2024 at 11:04 AM
2/2 Alex Hyafil (neurons & cognition)
Mireia Torralba (EEG, fMRI)
Klaus Wimmer (neurons & cognition)
Damian Blasi (language)
Juanma Toro (language)
upf.edu/web/mbc/acce...
You will learn all you need to do research in cognitive and computational neuroscience
Mireia Torralba (EEG, fMRI)
Klaus Wimmer (neurons & cognition)
Damian Blasi (language)
Juanma Toro (language)
upf.edu/web/mbc/acce...
You will learn all you need to do research in cognitive and computational neuroscience
Reposted by Martin Esparza-Iaizzo
One more week, one more superlist.
Really happy to see @jgmaz.bsky.social's paper with Jason Keller, @dudman.bsky.social et moi in there. It came out while the other place was going downhill, so we didn't share it
(as always thanks to the Western sensorimotor superlab for this great service)
Really happy to see @jgmaz.bsky.social's paper with Jason Keller, @dudman.bsky.social et moi in there. It came out while the other place was going downhill, so we didn't share it
(as always thanks to the Western sensorimotor superlab for this great service)
November 30, 2024 at 1:24 PM
One more week, one more superlist.
Really happy to see @jgmaz.bsky.social's paper with Jason Keller, @dudman.bsky.social et moi in there. It came out while the other place was going downhill, so we didn't share it
(as always thanks to the Western sensorimotor superlab for this great service)
Really happy to see @jgmaz.bsky.social's paper with Jason Keller, @dudman.bsky.social et moi in there. It came out while the other place was going downhill, so we didn't share it
(as always thanks to the Western sensorimotor superlab for this great service)
Reposted by Martin Esparza-Iaizzo
Important paper!
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)
www.biorxiv.org
November 22, 2024 at 2:47 PM
Important paper!
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)
www.biorxiv.org/content/bior...
Im not sure the Discussion fully delineates its radical implications.
No more...
* Place cells
* Grid cells, splitter cells, border cells
* Mirror neurons
* Reward neurons
* Conflict cells
(continued)