Mariarosaria De Rosa
@meryderosa.bsky.social
Postdoctoral Researcher at the University of Pittsburgh - Hillman Cancer Center -
Repair of oxidative damage at #telomeres in the @opreskolab.bsky.social
Repair of oxidative damage at #telomeres in the @opreskolab.bsky.social
I am excited to share that our study has just been published in Nature Communications! www.nature.com/articles/s41...
We uncovered a “dark side” of base excision repair of oxidative guanine damage at telomeres.
🧵⬇️
We uncovered a “dark side” of base excision repair of oxidative guanine damage at telomeres.
🧵⬇️
OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblasts - Nature Communications
Telomeres are prone to oxidative damage, particularly the formation of the common lesion 8-oxoguanine. This study shows that the processing of 8-oxoguanine at telomeres by the DNA repair enzymes OGG1 ...
www.nature.com
January 27, 2025 at 2:16 PM
I am excited to share that our study has just been published in Nature Communications! www.nature.com/articles/s41...
We uncovered a “dark side” of base excision repair of oxidative guanine damage at telomeres.
🧵⬇️
We uncovered a “dark side” of base excision repair of oxidative guanine damage at telomeres.
🧵⬇️