Melina Messing
@melinamessing.bsky.social
Immunologist | PKD Researcher I Postdoc @weimbs.bsky.social @ucsantabarbara.bsky.social | PhD @ubcmedicine.bsky.social | MSc @lunduniversity | German International | Hobby Cellist
Pinned
Melina Messing
@melinamessing.bsky.social
· Nov 23
Is ADPKD really just driven by the gene mutation? We think not.
We think that the gene mutation loads the gun and diet & lifestyle pulls the trigger.
That means that nutrition & lifestyle interventions can be disease-modifying.
Our recent paper here:
labs.mcdb.ucsb.edu/weimbs/thoma...
We think that the gene mutation loads the gun and diet & lifestyle pulls the trigger.
That means that nutrition & lifestyle interventions can be disease-modifying.
Our recent paper here:
labs.mcdb.ucsb.edu/weimbs/thoma...
When @weimbs.bsky.social discovered that nutrition and lifestyle could alter the course of PKD, it transformed my family's life—and my own. Today, I’m excited to share my first contribution as both a PKD scientist and patient, with the hope of helping others navigate this journey as well. ❤️👇
Reposted by Melina Messing
What can you eat in the Ren-Nu Program for people with polycystic kidney disease?
Listen to this discussion between @melinamessing.bsky.social and @weimbs.bsky.social.
Is this a super restrictive nutrition program that nobody could stick to long-term?
Tune in to find out: youtu.be/jU9jzJhCfic
Listen to this discussion between @melinamessing.bsky.social and @weimbs.bsky.social.
Is this a super restrictive nutrition program that nobody could stick to long-term?
Tune in to find out: youtu.be/jU9jzJhCfic
What Foods are in the Ren-Nu Program?
YouTube video by Santa Barbara Nutrients
youtu.be
March 17, 2025 at 6:06 PM
What can you eat in the Ren-Nu Program for people with polycystic kidney disease?
Listen to this discussion between @melinamessing.bsky.social and @weimbs.bsky.social.
Is this a super restrictive nutrition program that nobody could stick to long-term?
Tune in to find out: youtu.be/jU9jzJhCfic
Listen to this discussion between @melinamessing.bsky.social and @weimbs.bsky.social.
Is this a super restrictive nutrition program that nobody could stick to long-term?
Tune in to find out: youtu.be/jU9jzJhCfic
Curious about the Ren-Nu nutrition & lifestyle program for PKD? 🌱🥑 Watch the discussion & see how to get started! ⬇️
Discussion about the Ren-Nu nutrition & lifestyle program for people with polycystic kidney disease.
How to get started?
How to get started?
Video: How to get started with the Ren-Nu program even now!
Tip 1: Sign up on the wait list
Tip 2: Start with KetoCitra ahead of the program
--> Discussion in this video: youtu.be/FCu2fk2T_EU
Tip 1: Sign up on the wait list
Tip 2: Start with KetoCitra ahead of the program
--> Discussion in this video: youtu.be/FCu2fk2T_EU
February 21, 2025 at 4:31 AM
Curious about the Ren-Nu nutrition & lifestyle program for PKD? 🌱🥑 Watch the discussion & see how to get started! ⬇️
Reposted by Melina Messing
How the PKD-Free Alliance helps families with polycystic kidney disease to conceive PKD-free babies.
youtu.be/SOdkBI1M7u8
youtu.be/SOdkBI1M7u8
PKD-Free Babies. How?
YouTube video by Santa Barbara Nutrients
youtu.be
February 19, 2025 at 4:09 PM
How the PKD-Free Alliance helps families with polycystic kidney disease to conceive PKD-free babies.
youtu.be/SOdkBI1M7u8
youtu.be/SOdkBI1M7u8
Had a great conversation with Natasha from the PKD-FREE Alliance about how they’re helping families with PKD conceive PKD-free babies. Important work for breaking the cycle of inherited disease! Check it out here: www.youtube.com/watch?v=SOdk...
PKD-Free Babies. How?
YouTube video by Santa Barbara Nutrients
www.youtube.com
February 20, 2025 at 1:58 AM
Had a great conversation with Natasha from the PKD-FREE Alliance about how they’re helping families with PKD conceive PKD-free babies. Important work for breaking the cycle of inherited disease! Check it out here: www.youtube.com/watch?v=SOdk...
The English Version: My dad’s incredible journey to improving and maintaining kidney function—after transplant! He implemented KMT post-transplant to support his health. His story challenges the norm and shows the power of nutrition.
Yes, nutrition matters, even post-transplant!
Yes, nutrition matters, even post-transplant!
Ketogenic lifestyle AFTER kidney transplantation to help maintain kidney function?
Find out what happened to Manfred, who has polycystic kidney disease:
youtu.be/o_3oXym5-pw
Find out what happened to Manfred, who has polycystic kidney disease:
youtu.be/o_3oXym5-pw
Ketogenic Diet After Kidney Transplantation. What Happened?
YouTube video by Santa Barbara Nutrients
youtu.be
February 14, 2025 at 5:59 PM
The English Version: My dad’s incredible journey to improving and maintaining kidney function—after transplant! He implemented KMT post-transplant to support his health. His story challenges the norm and shows the power of nutrition.
Yes, nutrition matters, even post-transplant!
Yes, nutrition matters, even post-transplant!
My dad’s incredible journey to improving and maintaining kidney function—after transplant! He has PKD and implemented ketogenic metabolic therapy post-transplant to support his health. His story challenges the norm and shows the power of nutrition.
Yes, nutrition matters, even post-transplant!
Yes, nutrition matters, even post-transplant!
Ketogenic diet AFTER kidney transplantation. Wait, what? Why?
Manfred has polycystic kidney disease and implemented ketogenic metabolic therapy AFTER transplantation to maintain his renal function.
In German. English version coming up, stay tuned.
youtu.be/5OTUbvjh7ng
Manfred has polycystic kidney disease and implemented ketogenic metabolic therapy AFTER transplantation to maintain his renal function.
In German. English version coming up, stay tuned.
youtu.be/5OTUbvjh7ng
Ketogene Diät nach der Nierentransplantation? Was passiert?
YouTube video by Santa Barbara Nutrients
youtu.be
February 10, 2025 at 5:57 PM
My dad’s incredible journey to improving and maintaining kidney function—after transplant! He has PKD and implemented ketogenic metabolic therapy post-transplant to support his health. His story challenges the norm and shows the power of nutrition.
Yes, nutrition matters, even post-transplant!
Yes, nutrition matters, even post-transplant!
Reposted by Melina Messing
Mast cells locally secrete histamine during exercise, triggering activation of H1 and H2 receptors on myeloid and vascular cells, thereby affecting the exercise-induced metabolic and transcriptional adaptive response @cp-cellmetabolism.bsky.social
www.cell.com/cell-metabol...
www.cell.com/cell-metabol...
February 7, 2025 at 3:06 AM
Mast cells locally secrete histamine during exercise, triggering activation of H1 and H2 receptors on myeloid and vascular cells, thereby affecting the exercise-induced metabolic and transcriptional adaptive response @cp-cellmetabolism.bsky.social
www.cell.com/cell-metabol...
www.cell.com/cell-metabol...
Reposted by Melina Messing
Type-2 innate signals are dispensable for skeletal #muscle #regeneration and #pathology linked to #Duchenne muscular #dystrophy.
-> www.embopress.org/doi/full/10....
-> www.embopress.org/doi/full/10....
February 5, 2025 at 7:31 AM
Type-2 innate signals are dispensable for skeletal #muscle #regeneration and #pathology linked to #Duchenne muscular #dystrophy.
-> www.embopress.org/doi/full/10....
-> www.embopress.org/doi/full/10....
New paper alert! 🚨 Not what we expected.
In @emboreports.org, we show eosinophils & STAT6 have a negligible role in muscle regeneration & DMD—contrary to prior research.
Negative data matters. It moves science forward. 💡🔬
www.embopress.org/doi/full/10....
In @emboreports.org, we show eosinophils & STAT6 have a negligible role in muscle regeneration & DMD—contrary to prior research.
Negative data matters. It moves science forward. 💡🔬
www.embopress.org/doi/full/10....
Type-2 innate signals are dispensable for skeletal muscle regeneration and pathology linked to Duchenne muscular dystrophy | EMBO reports
imageimageContrary to prior data, this study shows that neither eosinophils nor STAT6-mediated
IL-4/IL-13 signaling contribute significantly to muscle repair after acute injury
or in Duchenne muscular...
www.embopress.org
February 4, 2025 at 11:20 PM
New paper alert! 🚨 Not what we expected.
In @emboreports.org, we show eosinophils & STAT6 have a negligible role in muscle regeneration & DMD—contrary to prior research.
Negative data matters. It moves science forward. 💡🔬
www.embopress.org/doi/full/10....
In @emboreports.org, we show eosinophils & STAT6 have a negligible role in muscle regeneration & DMD—contrary to prior research.
Negative data matters. It moves science forward. 💡🔬
www.embopress.org/doi/full/10....
Exciting times ahead for the PKD community! We're transforming renal nutrition with the soon-to-be relaunched Ren-Nu program. Catch this brief discussion with @weimbs.bsky.social and me to see what’s in store!
The Ren-Nu renal nutrition program for individuals with POLYCYSTIC KIDNEY DISEASE will soon be re-launched.
Brief discussion and preview with @melinamessing.bsky.social and @weimbs.bsky.social
youtu.be/XmCR05SGdgo
Brief discussion and preview with @melinamessing.bsky.social and @weimbs.bsky.social
youtu.be/XmCR05SGdgo
Preview of Ren-Nu Program Launch
YouTube video by Santa Barbara Nutrients
youtu.be
February 3, 2025 at 7:07 PM
Exciting times ahead for the PKD community! We're transforming renal nutrition with the soon-to-be relaunched Ren-Nu program. Catch this brief discussion with @weimbs.bsky.social and me to see what’s in store!
🤯 This can't be real...
Wild commercial.
The message: keep eating all the things that gave you diabetes and just take this pill. Surely, you won’t mind suddenly worsened kidney function, or a little life-threatening infection around the anus and genitals, right?
youtu.be/1tigKn7iqwg
The message: keep eating all the things that gave you diabetes and just take this pill. Surely, you won’t mind suddenly worsened kidney function, or a little life-threatening infection around the anus and genitals, right?
youtu.be/1tigKn7iqwg
Jardiance Commercial #4 (2024 & 2025)
YouTube video by Commercial Archivist
youtu.be
January 31, 2025 at 3:38 AM
🤯 This can't be real...
Reposted by Melina Messing
Everything you were told about potassium and kidneys may be wrong.
Take a look at this guest blog post by nephrologist Dr. Majd Isreb from the Integrative Kidney Institute commenting on a new study.
santabarbaranutrients.com/blogs/kidney...
Take a look at this guest blog post by nephrologist Dr. Majd Isreb from the Integrative Kidney Institute commenting on a new study.
santabarbaranutrients.com/blogs/kidney...
January 22, 2025 at 3:36 AM
Everything you were told about potassium and kidneys may be wrong.
Take a look at this guest blog post by nephrologist Dr. Majd Isreb from the Integrative Kidney Institute commenting on a new study.
santabarbaranutrients.com/blogs/kidney...
Take a look at this guest blog post by nephrologist Dr. Majd Isreb from the Integrative Kidney Institute commenting on a new study.
santabarbaranutrients.com/blogs/kidney...
Reposted by Melina Messing
Thinking of using a GLP1 drug?
OMG, this large study just came out showing...
--> 98% increased risk of any psychiatric disorders.
--> 195% higher risk of major depression, a 108% increased risk for anxiety, and a 106% elevated risk for suicidal behavior.
www.nature.com/articles/s41...
OMG, this large study just came out showing...
--> 98% increased risk of any psychiatric disorders.
--> 195% higher risk of major depression, a 108% increased risk for anxiety, and a 106% elevated risk for suicidal behavior.
www.nature.com/articles/s41...
The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy - Scientific Reports
Scientific Reports - The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy
www.nature.com
January 22, 2025 at 3:42 PM
Thinking of using a GLP1 drug?
OMG, this large study just came out showing...
--> 98% increased risk of any psychiatric disorders.
--> 195% higher risk of major depression, a 108% increased risk for anxiety, and a 106% elevated risk for suicidal behavior.
www.nature.com/articles/s41...
OMG, this large study just came out showing...
--> 98% increased risk of any psychiatric disorders.
--> 195% higher risk of major depression, a 108% increased risk for anxiety, and a 106% elevated risk for suicidal behavior.
www.nature.com/articles/s41...
Exciting news! Welcome to the team Dr. Johnson!
I am excited to welcome Dr. Richard Johnson on Santa Barbara Nutrients' advisory board! Dr. Johnson is one of the most influential nephrologists of our time, and a leader in research on metabolism and kidney disease.
News Release:
santabarbaranutrients.com/blogs/news/s...
News Release:
santabarbaranutrients.com/blogs/news/s...
Santa Barbara Nutrients Appoints Dr. Richard J. Johnson to Advisory Board
SANTA BARBARA, CA, UNITED STATES, January 22, 2025
Santa Barbara Nutrients, Inc., a leader in developing medical foods and nutritional programs for kidney health, is pleased to announce the appointmen...
santabarbaranutrients.com
January 31, 2025 at 3:36 AM
Exciting news! Welcome to the team Dr. Johnson!
Reposted by Melina Messing
KetoCitra is NOT just another supplement—it’s a medical food designed for PKD & CKD:
✔️ FDA-registered manufacturing
✔️ 3rd-party tested for quality
✔️ Science-backed ingredients
Watch Jacob Kingaard explain more:
✔️ FDA-registered manufacturing
✔️ 3rd-party tested for quality
✔️ Science-backed ingredients
Watch Jacob Kingaard explain more:
KetoCitra Manufacturing and Quality Control
What makes the medical food KetoCitra different from supplements? SBN's Director of Manufacturing and Product Development, Jacob Kingaard, explains the rigor...
buff.ly
January 3, 2025 at 2:00 PM
KetoCitra is NOT just another supplement—it’s a medical food designed for PKD & CKD:
✔️ FDA-registered manufacturing
✔️ 3rd-party tested for quality
✔️ Science-backed ingredients
Watch Jacob Kingaard explain more:
✔️ FDA-registered manufacturing
✔️ 3rd-party tested for quality
✔️ Science-backed ingredients
Watch Jacob Kingaard explain more:
🎙️🧠 Had an amazing conversation with NightmareRH about how nutritional changes have shaped our journeys with PKD! We dive into the real-life impact of these changes and what they mean for managing the disease. 🌱💪
📺 Don’t miss it: www.youtube.com/watch?v=TBPl...
📺 Don’t miss it: www.youtube.com/watch?v=TBPl...
PKD Awareness Day 5 - Dr. Melina Messing Interview PKD Patient
YouTube video by NightmareRH
www.youtube.com
December 19, 2024 at 5:41 AM
🎙️🧠 Had an amazing conversation with NightmareRH about how nutritional changes have shaped our journeys with PKD! We dive into the real-life impact of these changes and what they mean for managing the disease. 🌱💪
📺 Don’t miss it: www.youtube.com/watch?v=TBPl...
📺 Don’t miss it: www.youtube.com/watch?v=TBPl...
🎉 Huge thanks to @NightmareRH for raising funds for PKD research after learning he has PKD. He’s supporting the @weimbs.bsky.social lab, whose groundbreaking work shows nutritional changes can slow PKD progression! 🥗💜
Donate here: tiltify.com/@nightmarerh...
Every dollar counts!
Donate here: tiltify.com/@nightmarerh...
Every dollar counts!
December 14, 2024 at 3:07 AM
🎉 Huge thanks to @NightmareRH for raising funds for PKD research after learning he has PKD. He’s supporting the @weimbs.bsky.social lab, whose groundbreaking work shows nutritional changes can slow PKD progression! 🥗💜
Donate here: tiltify.com/@nightmarerh...
Every dollar counts!
Donate here: tiltify.com/@nightmarerh...
Every dollar counts!
Reposted by Melina Messing
Are you or someone you know navigating chronic kidney concerns? The Ren-Nu™ Program offers a sustainable, science-based approach to kidney health.
This isn’t just a diet—it’s a lifestyle, supported by a team of experts and a community of peers. 👉https://buff.ly/4fz1fAE
This isn’t just a diet—it’s a lifestyle, supported by a team of experts and a community of peers. 👉https://buff.ly/4fz1fAE
December 10, 2024 at 1:00 PM
Are you or someone you know navigating chronic kidney concerns? The Ren-Nu™ Program offers a sustainable, science-based approach to kidney health.
This isn’t just a diet—it’s a lifestyle, supported by a team of experts and a community of peers. 👉https://buff.ly/4fz1fAE
This isn’t just a diet—it’s a lifestyle, supported by a team of experts and a community of peers. 👉https://buff.ly/4fz1fAE
Reposted by Melina Messing
Kidney stroma and immune cells interact during inflammation in childhood-onset lupus nephritis
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
November 28, 2024 at 12:15 PM
Kidney stroma and immune cells interact during inflammation in childhood-onset lupus nephritis
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Melina Messing
A toxic relationship?
As the world negotiates a global #PlasticsTreaty this week, researchers call for ultra-processed foods & plastics to be tackled together
#INC5 #UPFs #FoodSystems #PlasticPollution #ecotox #diets
@stuartgillespie.bsky.social @fpffoundation.bsky.social
👉https://rdcu.be/d1scp
As the world negotiates a global #PlasticsTreaty this week, researchers call for ultra-processed foods & plastics to be tackled together
#INC5 #UPFs #FoodSystems #PlasticPollution #ecotox #diets
@stuartgillespie.bsky.social @fpffoundation.bsky.social
👉https://rdcu.be/d1scp
November 26, 2024 at 3:01 AM
A toxic relationship?
As the world negotiates a global #PlasticsTreaty this week, researchers call for ultra-processed foods & plastics to be tackled together
#INC5 #UPFs #FoodSystems #PlasticPollution #ecotox #diets
@stuartgillespie.bsky.social @fpffoundation.bsky.social
👉https://rdcu.be/d1scp
As the world negotiates a global #PlasticsTreaty this week, researchers call for ultra-processed foods & plastics to be tackled together
#INC5 #UPFs #FoodSystems #PlasticPollution #ecotox #diets
@stuartgillespie.bsky.social @fpffoundation.bsky.social
👉https://rdcu.be/d1scp
💻 Working from home with my Tollers. 🐕 Productivity level: adorable. ❤️🐾
November 26, 2024 at 1:15 AM
💻 Working from home with my Tollers. 🐕 Productivity level: adorable. ❤️🐾
🎶 🎻✨Last night's SBCC Symphony concert was an absolute treat! We performed an incredible program featuring timeless classics and new favorites. Relive the magic or catch what you missed here: www.youtube.com/watch?v=fS9H...
SBCC Symphony Concert, November 24, 2024
YouTube video by SBCC Music Department
www.youtube.com
November 25, 2024 at 11:56 PM
🎶 🎻✨Last night's SBCC Symphony concert was an absolute treat! We performed an incredible program featuring timeless classics and new favorites. Relive the magic or catch what you missed here: www.youtube.com/watch?v=fS9H...
When @weimbs.bsky.social discovered that nutrition and lifestyle could alter the course of PKD, it transformed my family's life—and my own. Today, I’m excited to share my first contribution as both a PKD scientist and patient, with the hope of helping others navigate this journey as well. ❤️👇
Is ADPKD really just driven by the gene mutation? We think not.
We think that the gene mutation loads the gun and diet & lifestyle pulls the trigger.
That means that nutrition & lifestyle interventions can be disease-modifying.
Our recent paper here:
labs.mcdb.ucsb.edu/weimbs/thoma...
We think that the gene mutation loads the gun and diet & lifestyle pulls the trigger.
That means that nutrition & lifestyle interventions can be disease-modifying.
Our recent paper here:
labs.mcdb.ucsb.edu/weimbs/thoma...
November 23, 2024 at 10:12 PM
When @weimbs.bsky.social discovered that nutrition and lifestyle could alter the course of PKD, it transformed my family's life—and my own. Today, I’m excited to share my first contribution as both a PKD scientist and patient, with the hope of helping others navigate this journey as well. ❤️👇
Reposted by Melina Messing
Scary finding: Obesity at preschool age predisposes to kidney disease in adulthood.
Start conservative nutrition & lifestyle intervention EARLY
www.nature.com/articles/s41...
Start conservative nutrition & lifestyle intervention EARLY
www.nature.com/articles/s41...
Preschool age-specific obesity and later-life kidney health: a Mendelian randomization and colocalization study - International Journal of Obesity
International Journal of Obesity - Preschool age-specific obesity and later-life kidney health: a Mendelian randomization and colocalization study
www.nature.com
November 22, 2024 at 9:40 PM
Scary finding: Obesity at preschool age predisposes to kidney disease in adulthood.
Start conservative nutrition & lifestyle intervention EARLY
www.nature.com/articles/s41...
Start conservative nutrition & lifestyle intervention EARLY
www.nature.com/articles/s41...