Margaret Johnson
@mejohnson81.bsky.social
Associate Professor of Biophysics at Johns Hopkins. Theory, modeling, and computation. Living systems and statistical mechanics. https://sites.krieger.jhu.edu/johnson-lab/
Does protein dimerization always help targeting and dwell time on DNA? Not for a population! Dwell time is especially sensitive to spacing between DNA targets. Nonspecific binding and facilitated (1D) diffusion also play a key role. Super proud of Mankun Sang’s work!
doi.org/10.1101/2025...
doi.org/10.1101/2025...
July 11, 2025 at 4:23 PM
Does protein dimerization always help targeting and dwell time on DNA? Not for a population! Dwell time is especially sensitive to spacing between DNA targets. Nonspecific binding and facilitated (1D) diffusion also play a key role. Super proud of Mankun Sang’s work!
doi.org/10.1101/2025...
doi.org/10.1101/2025...