Megan Korn
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megan--korn.bsky.social
Megan Korn
@megan--korn.bsky.social
PhD Student @ Columbia University in the Steckelberg Lab - RNA structure + viruses| previously a research technician @ NYU in the Banh Lab and Emory ‘20 | runner, bird-watcher, amateur naturalist
hello world! For my first bluesky post, excited to share some of my work from NYU Langone, in a collaboration with the Serganov Lab. We did a deep dive into the mol mechanism of ApaH decapping: www.nature.com/articles/s41... I’m esp partial to the mass spec experiments - take a look!
ApaH decaps Np4N-capped RNAs in two alternative orientations - Nature Chemical Biology
This study shows how Escherichia coli ApaH hydrolyzes enigmatic Np4N alarmones and decaps Np4-capped RNAs, thereby impacting their lifetimes. Key features enable ApaH to bind RNA substrates in two ori...
www.nature.com
August 23, 2025 at 12:50 PM