New post! Here, I highlighted a recent review article on lactate to "fuel" my growing interests in immunometabolism.
mikhaeldm.substack.com/p/lactate-fr...
A very interesting review to read, which highlight the journey of lactate as metabolic waste to master immune regulator!
mikhaeldm.substack.com/p/lactate-fr...
A very interesting review to read, which highlight the journey of lactate as metabolic waste to master immune regulator!
August 6, 2025 at 2:50 PM
New post! Here, I highlighted a recent review article on lactate to "fuel" my growing interests in immunometabolism.
mikhaeldm.substack.com/p/lactate-fr...
A very interesting review to read, which highlight the journey of lactate as metabolic waste to master immune regulator!
mikhaeldm.substack.com/p/lactate-fr...
A very interesting review to read, which highlight the journey of lactate as metabolic waste to master immune regulator!
The authors showed that the 42-gene SoM scores was, to some extent, correlated with Tsang's lab 150-gene Immune Health Metric (IHM) (Fig. S5).
Considering that IHM was derived using monogenic immune disorders, the authors proposed that the IHM reflects genetic factors while SoM lifestyle factors.
Considering that IHM was derived using monogenic immune disorders, the authors proposed that the IHM reflects genetic factors while SoM lifestyle factors.
July 14, 2025 at 9:36 AM
The authors showed that the 42-gene SoM scores was, to some extent, correlated with Tsang's lab 150-gene Immune Health Metric (IHM) (Fig. S5).
Considering that IHM was derived using monogenic immune disorders, the authors proposed that the IHM reflects genetic factors while SoM lifestyle factors.
Considering that IHM was derived using monogenic immune disorders, the authors proposed that the IHM reflects genetic factors while SoM lifestyle factors.
Using publicly available single-cell data, the authors showed that the scores were associated with certain immune cell types (Figs. 2D-E).
Detrimental scores were associated with neutrophils, protective scores with T/NK cells and monocytes.
Detrimental scores were associated with neutrophils, protective scores with T/NK cells and monocytes.
July 14, 2025 at 9:36 AM
Using publicly available single-cell data, the authors showed that the scores were associated with certain immune cell types (Figs. 2D-E).
Detrimental scores were associated with neutrophils, protective scores with T/NK cells and monocytes.
Detrimental scores were associated with neutrophils, protective scores with T/NK cells and monocytes.
SoM scores, or specifically its protective module scores, were associated with favourable response to hydrocortisone in burn injury patients (Figs. 1F-G)
July 14, 2025 at 9:36 AM
SoM scores, or specifically its protective module scores, were associated with favourable response to hydrocortisone in burn injury patients (Figs. 1F-G)