@mdcp-journal.bsky.social
Tongue movement disorders can be subtle, varied, hard to classify, (and missed!) yet offer important diagnostic clues. Our review outlines a clinical framework for tongue MDs. https://loom.ly/6_glCDQ
January 13, 2026 at 7:08 PM
Tongue movement disorders can be subtle, varied, hard to classify, (and missed!) yet offer important diagnostic clues. Our review outlines a clinical framework for tongue MDs. https://loom.ly/6_glCDQ
João Moura and colleagues recently published a global overview of movement disorders associated with specific ethnic or geographic backgrounds. https://loom.ly/z8SNUK4
January 7, 2026 at 7:06 PM
João Moura and colleagues recently published a global overview of movement disorders associated with specific ethnic or geographic backgrounds. https://loom.ly/z8SNUK4
New MDCP Pearl: Levodopa-Carbidopa Intestinal Gel Improves Dyskinesia in Parkinson's Disease: Post Hoc Analysis from the COSMOS Study https://loom.ly/vSxgyuk
January 6, 2026 at 6:09 PM
New MDCP Pearl: Levodopa-Carbidopa Intestinal Gel Improves Dyskinesia in Parkinson's Disease: Post Hoc Analysis from the COSMOS Study https://loom.ly/vSxgyuk
In a 248-patient study—largest to date—we show SMWI detects loss of dorsolateral nigral hyperintensity ("swallow tail sign") with 92%SN, 96%SP, and κ=0.88 for degenerative parkinsonism. https://loom.ly/VaFEiNw
January 2, 2026 at 7:03 PM
In a 248-patient study—largest to date—we show SMWI detects loss of dorsolateral nigral hyperintensity ("swallow tail sign") with 92%SN, 96%SP, and κ=0.88 for degenerative parkinsonism. https://loom.ly/VaFEiNw
MDS Tourette Syndrome Study Group found no compelling evidence to make general clinical recommendations on complementary medicine for TS. Rather, they advise knowledge gap transparency when engaging patients about specific treatments. https://loom.ly/mMBjYSw
December 19, 2025 at 10:29 PM
MDS Tourette Syndrome Study Group found no compelling evidence to make general clinical recommendations on complementary medicine for TS. Rather, they advise knowledge gap transparency when engaging patients about specific treatments. https://loom.ly/mMBjYSw
Could DBS reshape the brain beyond symptom control?
Neuroimaging shows:
-Increased STN activity
-Mixed connectivity shifts in motor & non-motor networks
-Hippocampal atrophy—aging or DBS effect?What does this mean for long-term cognition?
What are the implication? Read more: https://loom.ly/AmBkTOs
Neuroimaging shows:
-Increased STN activity
-Mixed connectivity shifts in motor & non-motor networks
-Hippocampal atrophy—aging or DBS effect?What does this mean for long-term cognition?
What are the implication? Read more: https://loom.ly/AmBkTOs
December 17, 2025 at 1:03 PM
Could DBS reshape the brain beyond symptom control?
Neuroimaging shows:
-Increased STN activity
-Mixed connectivity shifts in motor & non-motor networks
-Hippocampal atrophy—aging or DBS effect?What does this mean for long-term cognition?
What are the implication? Read more: https://loom.ly/AmBkTOs
Neuroimaging shows:
-Increased STN activity
-Mixed connectivity shifts in motor & non-motor networks
-Hippocampal atrophy—aging or DBS effect?What does this mean for long-term cognition?
What are the implication? Read more: https://loom.ly/AmBkTOs
Menstrual cycle & pregnancy matter in Parkinsons!
60% of women with early-onset PD report perimenstrual worsening; 40% experience symptom changes during pregnancy/postpartum.
An unmet need for tailored guidelines!
An unmet need for tailored guidelines! https://loom.ly/Gcn02nA
60% of women with early-onset PD report perimenstrual worsening; 40% experience symptom changes during pregnancy/postpartum.
An unmet need for tailored guidelines!
An unmet need for tailored guidelines! https://loom.ly/Gcn02nA
December 11, 2025 at 1:03 PM
Menstrual cycle & pregnancy matter in Parkinsons!
60% of women with early-onset PD report perimenstrual worsening; 40% experience symptom changes during pregnancy/postpartum.
An unmet need for tailored guidelines!
An unmet need for tailored guidelines! https://loom.ly/Gcn02nA
60% of women with early-onset PD report perimenstrual worsening; 40% experience symptom changes during pregnancy/postpartum.
An unmet need for tailored guidelines!
An unmet need for tailored guidelines! https://loom.ly/Gcn02nA
New MDCP Pearl: Orthostatic Tremor Is Evoked by Muscle Load Without the Need for Orthostatic Position https://loom.ly/fLM3XHw
December 9, 2025 at 4:41 PM
New MDCP Pearl: Orthostatic Tremor Is Evoked by Muscle Load Without the Need for Orthostatic Position https://loom.ly/fLM3XHw
Deep Brain Stimulation isn’t just for motor symptoms—what about autonomic dysfunction in Parkinsons?
This scoping review maps evidence across GI, cardiovascular, urinary, thermoregulatory & respiratory domains.
Read more: https://loom.ly/TdaWKG0
This scoping review maps evidence across GI, cardiovascular, urinary, thermoregulatory & respiratory domains.
Read more: https://loom.ly/TdaWKG0
December 5, 2025 at 4:36 PM
Deep Brain Stimulation isn’t just for motor symptoms—what about autonomic dysfunction in Parkinsons?
This scoping review maps evidence across GI, cardiovascular, urinary, thermoregulatory & respiratory domains.
Read more: https://loom.ly/TdaWKG0
This scoping review maps evidence across GI, cardiovascular, urinary, thermoregulatory & respiratory domains.
Read more: https://loom.ly/TdaWKG0
Functional gait disorder is complex—6 existing phenotypic frameworks fail to fully capture its heterogeneity. Fung (2016) and Baik & Lang (2007) classify most cases, but inter-rater reliability remains low. The Future? Data-driven, objective tools for better classification. https://loom.ly/3NNoG8I
December 2, 2025 at 8:12 PM
Functional gait disorder is complex—6 existing phenotypic frameworks fail to fully capture its heterogeneity. Fung (2016) and Baik & Lang (2007) classify most cases, but inter-rater reliability remains low. The Future? Data-driven, objective tools for better classification. https://loom.ly/3NNoG8I
Staged bilateral focused ultrasound for essential tremor shows significant tremor control, but a new study highlights a possible higher rate of patient reported adverse effects. https://loom.ly/JSBbEkk
November 13, 2025 at 1:03 PM
Staged bilateral focused ultrasound for essential tremor shows significant tremor control, but a new study highlights a possible higher rate of patient reported adverse effects. https://loom.ly/JSBbEkk
New MDCP Pearl: Functional Head Tremor: Contrasting Features with Other Tremor Etiologies. https://doi.org/10.1002/mdc3.70205
November 12, 2025 at 4:27 PM
New MDCP Pearl: Functional Head Tremor: Contrasting Features with Other Tremor Etiologies. https://doi.org/10.1002/mdc3.70205
Freezing of gait in Parkinson’s can worsen dramatically in low-light conditions—72% frozen time vs. 40% in daylight. Lighting isn’t just environmental, it’s therapeutic. Consider illumination as part of your fall prevention strategy! https://loom.ly/Z53Rdl8
November 11, 2025 at 10:21 PM
Freezing of gait in Parkinson’s can worsen dramatically in low-light conditions—72% frozen time vs. 40% in daylight. Lighting isn’t just environmental, it’s therapeutic. Consider illumination as part of your fall prevention strategy! https://loom.ly/Z53Rdl8
Several tools to measure PD symptom severity require updating to address past limitations or new developments in clinimetrics and wearable technology, per COA Scientific Evaluation Committee’s state-of-the-art review of clinical outcome assessments. https://loom.ly/R_ia5KY
November 6, 2025 at 2:05 PM
Several tools to measure PD symptom severity require updating to address past limitations or new developments in clinimetrics and wearable technology, per COA Scientific Evaluation Committee’s state-of-the-art review of clinical outcome assessments. https://loom.ly/R_ia5KY
LABS-PD cohort data at 5 years post diagnosis linked specific prognoses to "tremor predominant” and “motor complications” subtypes. Further subtype stratification may guide prognostication, inform trial design, and support tailored care planning. https://loom.ly/WMoDRd8
November 6, 2025 at 1:03 PM
LABS-PD cohort data at 5 years post diagnosis linked specific prognoses to "tremor predominant” and “motor complications” subtypes. Further subtype stratification may guide prognostication, inform trial design, and support tailored care planning. https://loom.ly/WMoDRd8
Follow-up analysis of predictive value for initiation of dopaminergic therapy in early PD led MDS’s #COA Program to conclude that a subset of 11 patient-reported items from the MDS-UPDRS actually outperformed the full 20-item scale. https://loom.ly/Uxk8CLQ
November 5, 2025 at 6:48 PM
Follow-up analysis of predictive value for initiation of dopaminergic therapy in early PD led MDS’s #COA Program to conclude that a subset of 11 patient-reported items from the MDS-UPDRS actually outperformed the full 20-item scale. https://loom.ly/Uxk8CLQ
New MDCP Pearl: Differential Effects of Levodopa and Stimulation on Post-Surgery Freezing of Gait in Subthalamic Nucleus Deep Brain Stimulation Parkinson's Disease Patients: A Clinical and Kinematic Analysis.
https://loom.ly/Twv6N80
https://loom.ly/Twv6N80
November 5, 2025 at 3:27 PM
New MDCP Pearl: Differential Effects of Levodopa and Stimulation on Post-Surgery Freezing of Gait in Subthalamic Nucleus Deep Brain Stimulation Parkinson's Disease Patients: A Clinical and Kinematic Analysis.
https://loom.ly/Twv6N80
https://loom.ly/Twv6N80
Long-term follow-up of patients with mass social media–induced functional tic-like behaviors shows:
-76% improved or remitted
-Better outcomes with early diagnosis, younger age, male sex, fewer comorbidities, no depression
Early recognition & psychiatric care are key. https://loom.ly/L3M8c8o
-76% improved or remitted
-Better outcomes with early diagnosis, younger age, male sex, fewer comorbidities, no depression
Early recognition & psychiatric care are key. https://loom.ly/L3M8c8o
October 30, 2025 at 12:03 PM
Long-term follow-up of patients with mass social media–induced functional tic-like behaviors shows:
-76% improved or remitted
-Better outcomes with early diagnosis, younger age, male sex, fewer comorbidities, no depression
Early recognition & psychiatric care are key. https://loom.ly/L3M8c8o
-76% improved or remitted
-Better outcomes with early diagnosis, younger age, male sex, fewer comorbidities, no depression
Early recognition & psychiatric care are key. https://loom.ly/L3M8c8o
This MDS Task Force review of evidence-based wellness interventions for PD recommends a proactive, practical, multidisciplinary approach. https://loom.ly/4oNw7ak
October 29, 2025 at 5:05 PM
This MDS Task Force review of evidence-based wellness interventions for PD recommends a proactive, practical, multidisciplinary approach. https://loom.ly/4oNw7ak
GI symptoms in #Parkinsons are common—but often overlooked.
A novel interdisciplinary PDGI clinic model improves diagnosis, treatment & QoL by integrating neuro + gastro care. A scalable blueprint for tackling nonmotor symptoms! https://loom.ly/99HkQgo
A novel interdisciplinary PDGI clinic model improves diagnosis, treatment & QoL by integrating neuro + gastro care. A scalable blueprint for tackling nonmotor symptoms! https://loom.ly/99HkQgo
October 28, 2025 at 5:06 PM
GI symptoms in #Parkinsons are common—but often overlooked.
A novel interdisciplinary PDGI clinic model improves diagnosis, treatment & QoL by integrating neuro + gastro care. A scalable blueprint for tackling nonmotor symptoms! https://loom.ly/99HkQgo
A novel interdisciplinary PDGI clinic model improves diagnosis, treatment & QoL by integrating neuro + gastro care. A scalable blueprint for tackling nonmotor symptoms! https://loom.ly/99HkQgo
In PD, cognitive decline remains a major challenge. This new study shows that elevated CSF DOPA decarboxylase (DDC) levels predict cognitive deterioration independent of dopaminergic therapy. Could DDC be your next prognostic biomarker? https://loom.ly/btGIhxc
October 22, 2025 at 5:05 PM
In PD, cognitive decline remains a major challenge. This new study shows that elevated CSF DOPA decarboxylase (DDC) levels predict cognitive deterioration independent of dopaminergic therapy. Could DDC be your next prognostic biomarker? https://loom.ly/btGIhxc
Meta-analysis shows botulinum toxin offers moderate, patient-reported benefit for upper limb tremor (ET & DT), with no consistent effect on clinician-rated scores or grip strength. No clear “best” injection strategy yet—more trials needed! https://loom.ly/y__Uvqg
October 17, 2025 at 9:13 PM
Meta-analysis shows botulinum toxin offers moderate, patient-reported benefit for upper limb tremor (ET & DT), with no consistent effect on clinician-rated scores or grip strength. No clear “best” injection strategy yet—more trials needed! https://loom.ly/y__Uvqg
Slow-motion videography reveals “air writing” before pen hits paper in writer’s cramp—capturing subtle motor signs missed at normal speed. A simple smartphone tool, big clinical insights! https://loom.ly/RQPqYVQ
October 14, 2025 at 9:12 PM
Slow-motion videography reveals “air writing” before pen hits paper in writer’s cramp—capturing subtle motor signs missed at normal speed. A simple smartphone tool, big clinical insights! https://loom.ly/RQPqYVQ
Balance problems in Huntington’s disease start early—even before motor symptoms appear! Using a simple body sway test, researchers tracked progressive balance loss across all stages. Early detection = earlier intervention! https://loom.ly/7CZFC68
October 8, 2025 at 9:11 PM
Balance problems in Huntington’s disease start early—even before motor symptoms appear! Using a simple body sway test, researchers tracked progressive balance loss across all stages. Early detection = earlier intervention! https://loom.ly/7CZFC68
New MDCP Pearl: The Impact of Deep Brain Stimulation of the Subthalamic Nucleus on Sleep–Wake Function and Circadian Rhythms in Patients with Parkinson's Disease. https://loom.ly/UX6YW_0
October 3, 2025 at 3:13 PM
New MDCP Pearl: The Impact of Deep Brain Stimulation of the Subthalamic Nucleus on Sleep–Wake Function and Circadian Rhythms in Patients with Parkinson's Disease. https://loom.ly/UX6YW_0