McCabe Lab
@mccabelab.org
Research in our laboratory is directed towards understanding the biology of motor system circuits & synapses in tandem with exploiting these insights to ameliorate motor system neurodegenerative diseases including ALS, FTD & SMA https://mccabelab.org
Weird results from CRISPR/Cas9 Homology Directed Repair (HDR) based genome editing? We show that frequently the HDR template vector becomes incorporated into the genome causing all sorts of problems. For #Drosophila, we develop a vector to detect these unwanted events
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
August 12, 2025 at 1:19 PM
Weird results from CRISPR/Cas9 Homology Directed Repair (HDR) based genome editing? We show that frequently the HDR template vector becomes incorporated into the genome causing all sorts of problems. For #Drosophila, we develop a vector to detect these unwanted events
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Many congratulations to lab member Medha Raman for winning the EPFL final of MT180 - My Thesis in 180 seconds
March 30, 2025 at 3:36 PM
Many congratulations to lab member Medha Raman for winning the EPFL final of MT180 - My Thesis in 180 seconds