Marie-Cécile Caillaud
@mc-caillaud.bsky.social
Research director at CNRS 🇨🇵 | RDP laboratory | @ERC research | Plant cell biology | cytoskeleton | phosphoinositides | biophysics 🌿🧪🧫🔬🧬 | Passionate about cell division 🤓
#FemmesetSciences
Inclusive working environment, we are hiring!
#FemmesetSciences
Inclusive working environment, we are hiring!
14èmes Journées Scientifiques et Techniques du Réseau des Microscopistes INRAE - du 5 au 7 novembre 2025
rmui-2025.journees.inrae.fr
rmui-2025.journees.inrae.fr
October 8, 2025 at 8:50 AM
14èmes Journées Scientifiques et Techniques du Réseau des Microscopistes INRAE - du 5 au 7 novembre 2025
rmui-2025.journees.inrae.fr
rmui-2025.journees.inrae.fr
👀
ABA reduces primary plasmodesmata density in newly forming cell plates.
ABA reduces primary plasmodesmata density in newly forming cell plates.
September 5, 2025 at 7:14 PM
👀
ABA reduces primary plasmodesmata density in newly forming cell plates.
ABA reduces primary plasmodesmata density in newly forming cell plates.
It's time to say bye after these thrilling 2 days of conference #EPCC2025 at @ensdelyon.bsky.social @rdplab.bsky.social
✨️Thank you to all the participants 🤩✨️
And congrats to Mariana Romeiro Motta @marianattom.bsky.social for winning the best poster price 👏👏
✨️Thank you to all the participants 🤩✨️
And congrats to Mariana Romeiro Motta @marianattom.bsky.social for winning the best poster price 👏👏
September 5, 2025 at 1:22 PM
It's time to say bye after these thrilling 2 days of conference #EPCC2025 at @ensdelyon.bsky.social @rdplab.bsky.social
✨️Thank you to all the participants 🤩✨️
And congrats to Mariana Romeiro Motta @marianattom.bsky.social for winning the best poster price 👏👏
✨️Thank you to all the participants 🤩✨️
And congrats to Mariana Romeiro Motta @marianattom.bsky.social for winning the best poster price 👏👏
September 4, 2025 at 7:51 PM
First day at #EPCC2025 great science, good mood, french style @ensdelyon.bsky.social @rdplab.bsky.social
September 4, 2025 at 7:47 PM
First day at #EPCC2025 great science, good mood, french style @ensdelyon.bsky.social @rdplab.bsky.social
The microtubule links between spindle poles and the apicobasal cortex were strongly reduced after F-actin disruption (LatB), correlating with spindle tilting. This suggests F-actin helps anchor the spindle to the cortex once the PPB has disassembled.
August 25, 2025 at 9:21 AM
The microtubule links between spindle poles and the apicobasal cortex were strongly reduced after F-actin disruption (LatB), correlating with spindle tilting. This suggests F-actin helps anchor the spindle to the cortex once the PPB has disassembled.
In WT plants, expansion microscopy with spindle immunolabeling showed microtubule connections between spindle poles and the apicobasal cortex.
August 25, 2025 at 9:15 AM
In WT plants, expansion microscopy with spindle immunolabeling showed microtubule connections between spindle poles and the apicobasal cortex.
F-Actin maintains spindle orientation against cellular geometry.
In WT, spindle poles aligned with the PPB, while LatB-treated and act7-4 cells showed spindle misalignment at metaphase.
In WT, spindle poles aligned with the PPB, while LatB-treated and act7-4 cells showed spindle misalignment at metaphase.
August 25, 2025 at 9:06 AM
F-Actin maintains spindle orientation against cellular geometry.
In WT, spindle poles aligned with the PPB, while LatB-treated and act7-4 cells showed spindle misalignment at metaphase.
In WT, spindle poles aligned with the PPB, while LatB-treated and act7-4 cells showed spindle misalignment at metaphase.
Actin perturbation disrupts the alignment between the PPB and the division site.
Time-lapse analysis of dividing trichoblast in root expressing the microtubule reporter IQD8-GFP (green) and the plasma membrane marker 2xmCh2xPHFAPP1 (magenta), after 2h-LatB.
Time-lapse analysis of dividing trichoblast in root expressing the microtubule reporter IQD8-GFP (green) and the plasma membrane marker 2xmCh2xPHFAPP1 (magenta), after 2h-LatB.
August 25, 2025 at 9:03 AM
Actin perturbation disrupts the alignment between the PPB and the division site.
Time-lapse analysis of dividing trichoblast in root expressing the microtubule reporter IQD8-GFP (green) and the plasma membrane marker 2xmCh2xPHFAPP1 (magenta), after 2h-LatB.
Time-lapse analysis of dividing trichoblast in root expressing the microtubule reporter IQD8-GFP (green) and the plasma membrane marker 2xmCh2xPHFAPP1 (magenta), after 2h-LatB.
Actin perturbations reset division orientation toward geometry-driven mechanisms:
Actin provides essential spatial cues that reinforce robust patterning, particularly when geometric constraints are not aligned with growth direction.
Actin provides essential spatial cues that reinforce robust patterning, particularly when geometric constraints are not aligned with growth direction.
August 25, 2025 at 9:00 AM
Actin perturbations reset division orientation toward geometry-driven mechanisms:
Actin provides essential spatial cues that reinforce robust patterning, particularly when geometric constraints are not aligned with growth direction.
Actin provides essential spatial cues that reinforce robust patterning, particularly when geometric constraints are not aligned with growth direction.
In WT roots, divisions were mainly transverse anticlinal, whereas actin disruption caused abnormal longitudinal or periclinal divisions.
August 25, 2025 at 8:57 AM
In WT roots, divisions were mainly transverse anticlinal, whereas actin disruption caused abnormal longitudinal or periclinal divisions.
PPB-defective mutants (ton1a, trm678) show tilted but laterally confined divisions, suggesting safeguards prevent apicobasal division
F-actin (cyan) accumulates at apicobasal cell faces during division, supporting a potential instructive role for F-actin in orienting the division plane
F-actin (cyan) accumulates at apicobasal cell faces during division, supporting a potential instructive role for F-actin in orienting the division plane
August 25, 2025 at 8:55 AM
PPB-defective mutants (ton1a, trm678) show tilted but laterally confined divisions, suggesting safeguards prevent apicobasal division
F-actin (cyan) accumulates at apicobasal cell faces during division, supporting a potential instructive role for F-actin in orienting the division plane
F-actin (cyan) accumulates at apicobasal cell faces during division, supporting a potential instructive role for F-actin in orienting the division plane
The preprophase band (PPB) sets division orientation before mitosis.
In the absence of PPB, in the trm678 mutant, division planes in atrichoblasts no longer followed the shortest geometric path but appeared randomly anchored along the lateral surface.
In the absence of PPB, in the trm678 mutant, division planes in atrichoblasts no longer followed the shortest geometric path but appeared randomly anchored along the lateral surface.
August 25, 2025 at 8:50 AM
The preprophase band (PPB) sets division orientation before mitosis.
In the absence of PPB, in the trm678 mutant, division planes in atrichoblasts no longer followed the shortest geometric path but appeared randomly anchored along the lateral surface.
In the absence of PPB, in the trm678 mutant, division planes in atrichoblasts no longer followed the shortest geometric path but appeared randomly anchored along the lateral surface.
Errera’s rule states that plant cells tend to divide along the shortest path, splitting the cell into two equal volumes, much like a soap bubble dividing into two smaller bubbles:
Here, we found that root epidermal cells do not systematically divide according to area minimisation
Here, we found that root epidermal cells do not systematically divide according to area minimisation
August 25, 2025 at 8:44 AM
Errera’s rule states that plant cells tend to divide along the shortest path, splitting the cell into two equal volumes, much like a soap bubble dividing into two smaller bubbles:
Here, we found that root epidermal cells do not systematically divide according to area minimisation
Here, we found that root epidermal cells do not systematically divide according to area minimisation
🤩 BEAUTIFULL highlight of our work by Sabine Muller now published in @currentbiology.bsky.social
👇
doi.org/10.1016/j.cu...
👇
doi.org/10.1016/j.cu...
June 24, 2025 at 1:16 PM
🤩 BEAUTIFULL highlight of our work by Sabine Muller now published in @currentbiology.bsky.social
👇
doi.org/10.1016/j.cu...
👇
doi.org/10.1016/j.cu...
All the good stuff comes to an end... It's time to head back to @rdplab.bsky.social after a fantastic week at #ICAR2025
June 20, 2025 at 7:00 PM
All the good stuff comes to an end... It's time to head back to @rdplab.bsky.social after a fantastic week at #ICAR2025
A big thanks to all the speakers of the session on cell-to-cell communication #ICAR2025👏👏👏
@pdchristine.bsky.social
@pmarhavy.bsky.social
@matiasgleason.bsky.social
@rebeccaburkart.bsky.social
Dimitra Valadourou
🙏Many thanks to my co-chairs
@yvonjaillais.bsky.social
and Isabelle Fobis-Loisy
@pdchristine.bsky.social
@pmarhavy.bsky.social
@matiasgleason.bsky.social
@rebeccaburkart.bsky.social
Dimitra Valadourou
🙏Many thanks to my co-chairs
@yvonjaillais.bsky.social
and Isabelle Fobis-Loisy
June 20, 2025 at 6:38 PM
A big thanks to all the speakers of the session on cell-to-cell communication #ICAR2025👏👏👏
@pdchristine.bsky.social
@pmarhavy.bsky.social
@matiasgleason.bsky.social
@rebeccaburkart.bsky.social
Dimitra Valadourou
🙏Many thanks to my co-chairs
@yvonjaillais.bsky.social
and Isabelle Fobis-Loisy
@pdchristine.bsky.social
@pmarhavy.bsky.social
@matiasgleason.bsky.social
@rebeccaburkart.bsky.social
Dimitra Valadourou
🙏Many thanks to my co-chairs
@yvonjaillais.bsky.social
and Isabelle Fobis-Loisy
We now all love seed mucilage here at #ICAR2025 after the great talk of Susana Saez-Aguayo 🔬🧬🌱
#mucilovers
#mucilovers
June 20, 2025 at 9:56 AM
We now all love seed mucilage here at #ICAR2025 after the great talk of Susana Saez-Aguayo 🔬🧬🌱
#mucilovers
#mucilovers
Our very own Camila Goldy @camilagoldy.bsky.social @rdplab.bsky.social @ensdelyon.bsky.social @embo.org now on stage shading light on the role of the actin cytoskeleton in cell division orientation against geometry #ICAR2025
😍😍
#womeninSTEM #proudPI
😍😍
#womeninSTEM #proudPI
June 18, 2025 at 10:31 AM
Our very own Camila Goldy @camilagoldy.bsky.social @rdplab.bsky.social @ensdelyon.bsky.social @embo.org now on stage shading light on the role of the actin cytoskeleton in cell division orientation against geometry #ICAR2025
😍😍
#womeninSTEM #proudPI
😍😍
#womeninSTEM #proudPI
Superb analytical study on POK2, master regulator of cell division orientation by Sabine Muller here at the #ICAR2025
More details here
👇
www.nature.com/articles/s41...
More details here
👇
www.nature.com/articles/s41...
June 18, 2025 at 9:58 AM
Superb analytical study on POK2, master regulator of cell division orientation by Sabine Muller here at the #ICAR2025
More details here
👇
www.nature.com/articles/s41...
More details here
👇
www.nature.com/articles/s41...
Take home message: "talk to your neighbour" fantastic work form Gwyneth Ingram's team @rdplab.bsky.social @ensdelyon.bsky.social
About the dialogue between the embryo and the endosperm 🤓🔬🧬🧪
#ICAR2025
About the dialogue between the embryo and the endosperm 🤓🔬🧬🧪
#ICAR2025
June 18, 2025 at 8:06 AM
Take home message: "talk to your neighbour" fantastic work form Gwyneth Ingram's team @rdplab.bsky.social @ensdelyon.bsky.social
About the dialogue between the embryo and the endosperm 🤓🔬🧬🧪
#ICAR2025
About the dialogue between the embryo and the endosperm 🤓🔬🧬🧪
#ICAR2025
Concurrent 2: Computational modeling of plant development and adaptation, with Adrien Oliveri @hadrienoliveri.bsky.social presenting his fantastic work on the formalisation of photropism and gravitropism
#ICAR2025
#ICAR2025
June 17, 2025 at 1:12 PM
Concurrent 2: Computational modeling of plant development and adaptation, with Adrien Oliveri @hadrienoliveri.bsky.social presenting his fantastic work on the formalisation of photropism and gravitropism
#ICAR2025
#ICAR2025
🚨 Time to register !
The European Plant Cytoskeletal Club is an informal meeting, focusing on research on plant cytoskeleton 🍀🧪🧬🔬
Where: ENS de Lyon @ensdelyon.bsky.social, hosted by the RDP laboratory @rdplab.bsky.social
When: the 4th and 5th of September 2025.
👇
epcc2025.sciencesconf.org
The European Plant Cytoskeletal Club is an informal meeting, focusing on research on plant cytoskeleton 🍀🧪🧬🔬
Where: ENS de Lyon @ensdelyon.bsky.social, hosted by the RDP laboratory @rdplab.bsky.social
When: the 4th and 5th of September 2025.
👇
epcc2025.sciencesconf.org
May 23, 2025 at 7:09 AM
🚨 Time to register !
The European Plant Cytoskeletal Club is an informal meeting, focusing on research on plant cytoskeleton 🍀🧪🧬🔬
Where: ENS de Lyon @ensdelyon.bsky.social, hosted by the RDP laboratory @rdplab.bsky.social
When: the 4th and 5th of September 2025.
👇
epcc2025.sciencesconf.org
The European Plant Cytoskeletal Club is an informal meeting, focusing on research on plant cytoskeleton 🍀🧪🧬🔬
Where: ENS de Lyon @ensdelyon.bsky.social, hosted by the RDP laboratory @rdplab.bsky.social
When: the 4th and 5th of September 2025.
👇
epcc2025.sciencesconf.org