Matt Bogyo
@mbogyo.bsky.social
Chemical biologist at Stanford with a love for covalent binding molecules and hydrolases.
This work shows that it is possible to find highly potent and selective covalent inhibitors of an enzyme target directly from small fragment libraries containing diverse electrophiles. These new tools can be used to study the function of these bacterial hydrolases which are important for virulence.
May 30, 2025 at 9:55 PM
This work shows that it is possible to find highly potent and selective covalent inhibitors of an enzyme target directly from small fragment libraries containing diverse electrophiles. These new tools can be used to study the function of these bacterial hydrolases which are important for virulence.
Great work. Nice to see it out here.
March 26, 2025 at 4:11 AM
Great work. Nice to see it out here.